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Sidopin 10mg Capsule



Sidopin 10mg Capsule is a tricyclic antidepressant. It is used in the treatment of insomnia (difficulty in sleeping). It is also used in patients intolerant of or unresponsive to alternative (Other) treatment options for depression and anxiety disorders.

Sidopin 10mg Capsule works by increasing the level of chemical messengers in the brain that stabilizes and enhances the mood. It is usually advised to take it before bedtime because it can make you feel drowsy. It can be taken with or without food, but you should take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed any dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to the doctor. Your dose will need to be gradually decreased when the doctor decides to stop it.

The most common side effects of this medicine include increased heart rate, blurred vision, dryness in the mouth, difficulty in urination and constipation. Initially, this medicine may also cause a sudden drop in the blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may even cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. It may also lead to weight gain in some people. Most of the common side effects tend to be mild and temporary. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects are rare.

Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. This medicine is not known to be addictive, but you can get extra side effects (withdrawal symptoms) if you stop taking it suddenly. If you notice any sudden mood change or get suicidal or self-harm thoughts, you must consult the doctor without delay. Also, remember to take this medicine as advised by the doctor as an overdose of this medication may lead to a serious health emergency. Consumption of alcohol should be avoided as alcohol interacts with this medicine to cause serious health issues.

Uses of Sidopin Capsule

Side effects of Sidopin Capsule

  • Increased heart rate
  • Weight gain
  • Dryness in mouth
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Constipation
  • Difficulty in urination

How to use Sidopin Capsule

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Sidopin 10mg Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Sidopin Capsule works

Sidopin 10mg Capsule is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

Safety Advice

It is unsafe to consume alcohol with Sidopin 10mg Capsule.
Sidopin 10mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Sidopin 10mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
The baby should be monitored carefully for excessive sleepiness, and adequate weight gain.
Sidopin 10mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Sidopin 10mg Capsule is safe to use in patients with kidney disease. No dose adjustment of Sidopin 10mg Capsule is recommended.
However, talk to your doctor if you have any underlying kidney disease.
Sidopin 10mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Sidopin 10mg Capsule may be needed. Please consult your doctor.

What if you forget to take Sidopin Capsule?

If you miss a dose of Sidopin 10mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Sidopin 10mg Capsule
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Quick Tips

  • Sidopin 10mg Capsule helps in the treatment of insomnia, depression and anxiety.
  • Inform your doctor if you notice behavioral changes, mood changes and suicidal thoughts while taking this medicine. 
  • Inform your doctor if you notice loss of consciousness,  agitation, reduced breathing rate, convulsions, muscle rigidity, and mouth dryness.
  • You may be asked for regular blood tests to monitor the blood cell count or level of sodium and sugar in the blood.
  • Do not drive or do anything that requires concentration until you know how drug affects you.
  • Do not stop taking the medication suddenly without talking to your doctor.

Interaction with Drugs

Taking Sidopin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Lizolan, Lidoford, Mapzolide
Brand(s): Trima, Rimarex, Morex
Brand(s): Moxicheck, Moxonex, Unsym

Patient Concerns

Depression insomnia and weight loss
Dr. Anuneet Sabharwal
Take Nexito 10mg in the morning and increase to 20mg daily
Alcoholic,chronic insomnia,depression,anxiety.
Dr. Anuneet Sabharwal
You will need to be admitted in a psychiatry ward for detoxification and motivational enhancementDo not try to stop alcohol on your own as it is dangerous and not recommended
Do you have any questions related to Sidopin 10mg Capsule ?


Q. Can I stop taking Sidopin abruptly?

No, you should always check with your doctor before you stop the treatment. Stopping the medicine abruptly may cause withdrawal effects. So, your doctor may reduce your dosage gradually before stopping the medicine completely. This helps to prevent a recurrence of the original symptoms of depression and reduce the chance of withdrawal effects.

Q. Does Sidopin cause withdrawal side effects?

Yes, stopping the use of Sidopin abruptly results in withdrawal symptoms which include insomnia (trouble falling asleep), irritability and excessive sweating. You should consult your doctor if you need to stop Sidopin who will advise gradual reduction of dose of Sidopin.

Q. When must Sidopin not be taken?

You should not take Sidopin if you have ever had an allergic reaction to antidepressants medicine (Sidopin), or any of the inactive ingredients of Sidopin. Avoid taking Sidopin if you have glaucoma (increased eye pressure), serious liver problems, are breastfeeding or are suffering from difficulty in passing urine. Do not take Sidopin if you are taking or have taken monoamine oxidase inhibitors (MAOIs) in the last two weeks or, suffer from mania (where you experience an abnormally elevated mood state) or are under 12 years of age.

Q. Can I use Sidopin for bipolar disorder?

Yes, Sidopin can be used in patients with bipolar disorder which means manic-depressive illness, in which there are periods of depression and periods of mood elevation.

Q. Can I drive while on Sidopin treatment?

Taking Sidopin may cause sleepiness, so you should avoid driving or working with machinery until the effect has worn off. Driving while taking Sidopin may cause sleep-driving. This refers to the instance of driving while not fully awake after taking a sleeping medicine, with loss of memory for the event and other serious side effects.

Q. What are the overdose symptoms of Sidopin?

Overdose of Sidopin can be mild or severe. Signs and symptoms of mild overdose include drowsiness, stupor, blurred vision and excessive dryness of the mouth. Severe overdose may cause loss of consciousness, reduced breathing rate, convulsions, low blood pressure, unusually fast heartbeat or palpitations. If you take too many capsules, contact your doctor immediately or seek emergency medical services in a nearby hospital.

Q. How long does it take for Sidopin to kick in?

It may take several weeks or longer for you to feel the full effect of Sidopin. Do not stop taking Sidopin without talking to your doctor, even if you feel well.

Q. Is Sidopin a sleeping pill?

Sidopin tablets are used for the treatment of insomnia (trouble falling asleep). It is especially helpful for people who have trouble staying asleep.

Q. Can I drink alcohol while on treatment with Sidopin?

No, you should not consume alcohol while taking Sidopin as alcohol can increase the severity of the sedative effects of Sidopin. This may also increase the risk of sleep-driving and other serious side effects.

Q. Is Sidopin addictive?

Generally Sidopin does not cause dependence and is therefore not addictive. But, you should not stop abruptly as it may cause temporary withdrawal symptoms.

Q. Can Sidopin cause suicidal thoughts?

Yes, Sidopin can cause suicidal thoughts. This is more common in people who have previously had thoughts about killing or harming themselves or if the person is a young adult less than 25 years who have a history of psychiatric conditions and was treated with an antidepressant. If you experience suicidal thoughts, contact your doctor or go to a hospital straight away. You may find it helpful to talk to a relative or close friend.

Q. Does Sidopin cause weight gain?

Sidopin may cause weight gain as well as loss of appetite, but it is not very common. Call your doctor if the weight gain or the loss of appetite is severe or does not go away.

Q. What is the best time to take Sidopin?

If you are taking Sidopin for insomnia, you should take it 30 minutes before bedtime and should confine your activities to those necessary to prepare for bed. Remember to take this medicine at the same time each day. If you are taking it for depression or anxiety, take it exactly as directed by your doctor.

Q. What are the side effects of Sidopin?

The side effects of Sidopin include nausea, vomiting, weakness or tiredness, dizziness, headache, hair loss, diarrhea, difficulty urinating, flushing and changes in appetite or weight. It may also cause increase in pupil size, dry mouth, mouth sores, changes in the way things taste, indigestion, constipation, excessive thirst and urination, ringing in your ears, changes in sex drive, swollen testicles, increased breast size, and milky discharge from nipples in females. It may make your skin more sensitive to sunlight, cause chills and excessive sweating.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
  1. Stahl SM, editor. Doxepin. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 211-17.
  2. Skidgel RA, Kaplan AP, Erdös EG. Histamine, Bradykinin, and Their Antagonists. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 923.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 430-31.
  4. Doxepin. San Diego: Somaxon Pharmaceuticals; 1969 [revised date]. [Accessed 22 Mar. 2019] (online) Available from:External Link
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:External Link
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