Information about Doxepin

    Doxepin uses

    Doxepin is used in the treatment of depression and insomnia.
    It is used in patients intolerant of or unresponsive to alternative treatment options for depression.

    How doxepin works

    Doxepin increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

    Common side effects of doxepin

    Sleepiness, Blurred vision, Increased heart rate, Weight gain, Dry mouth, Orthostatic hypotension (sudden lowering of blood pressure on standing), Constipation, Difficulty in urination

    Available Medicine for Doxepin

    • ₹54 to ₹127
      Sun Pharmaceutical Industries Ltd
      3 variant(s)
    • ₹26 to ₹87
      Intas Pharmaceuticals Ltd
      3 variant(s)
    • ₹75
      1 variant(s)
    • ₹40 to ₹78
      La Pharmaceuticals
      2 variant(s)
    • ₹25 to ₹35
      Seagull Pharmaceutical Pvt Ltd
      2 variant(s)
    • ₹25 to ₹39
      Shine Pharmaceuticals Ltd
      2 variant(s)
    • ₹45 to ₹70
      Tas Med India Pvt Ltd
      2 variant(s)
    • ₹14 to ₹29
      Torrent Pharmaceuticals Ltd
      3 variant(s)
    • ₹9
      Intas Pharmaceuticals Ltd
      1 variant(s)
    • ₹24
      RKG Pharma
      1 variant(s)

    Expert advice for Doxepin

    • The main dose should be taken at night as this drug may produce drowsiness or sleepiness.
    • It can take 4 to 6 weeks for Doxepin to start working.
    • You should continue the treatment for at least 6 months after you feel better to stop depression from coming back.
    • If your doctor asks you to stop Doxepin, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly.
    • Avoid driving or operating machinery as it may decrease alertness.
    • Avoid consuming alcohol when taking the Doxepin, as it may cause excessive drowsiness and calmness.
    • The addiction/dependence potential of Doxepin is very less.
    • It may be extremely dangerous in overdose.

    Frequently asked questions for Doxepin


    Q. Is Doxepin a tricyclic antidepressant, SSRI/ MAO inhibitor?
    Doxepin is a tricyclic antidepressant. It is not a SSRI (selective serotonin reuptake inhibitor) or a MAOi (monoamine oxidase inhibitor)
    Q. Is Doxepin a habit-forming/addictive or narcotic drug?
    No. Doxepin is not a habit-forming/addictive or narcotic drug. It might however cause certain withdrawal effects when the treatment is stopped abruptly. Hence, it is advisable to consult your doctor before stopping the treatment
    Q. Is Doxepin a sedative or sleeping pill?
    No. Doxepin is not a sedative or sleeping pill. However it might cause sleepiness as a side-effect
    Show More
    Q. Is Doxepin safe?
    Yes. Doxepin is relatively safe if used as recommended. In case of any side-effects, consult your doctor
    Q. Can I take doxepin with hydroxyzine, Ambien, Zoloft, Percocet, Wellbutrin, NyQuil, Atarax, Lunesta, and Prozac?
    Doxepin should not be taken with Zoloft (sertraline), Prozac (Fluoxetine), Wellbutrin (bupropion), Lunesta (eszopiclone), NyQuil (cold and flu medication), Percocet (oxycodone, acetaminophen), Prozac (fluoxetine), Atarax (hydroxyzine) and Ambien (zolpidem)
    Q. Does Doxepin cause weight gain, sleepiness or hair loss?
    Doxepin may cause weight gain, sleepiness or hair loss. If you experience any such symptoms, please consult your doctor
    Q. Does Doxepin help with pain or anxiety?
    Doxepin may be effective in the treatment of chronic neuropathic pain and anxiety.

    Content on this page was last updated on 11 September, 2017, by Dr. Varun Gupta (MD Pharmacology)