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Salamax Tablet DR

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 21 Sep 2025 | 10:16 PM (IST)
Salamax Tablet DR is a medicine used to treat various inflammatory conditions, including rheumatoid arthritis and psoriatic arthritis (joints), ulcerative colitis, and Crohn’s disease (bowel). It reduces swelling and inflammation by blocking certain chemicals in the body.
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General Information

The content is shown in English
Salamax Tablet DR image
Salamax Tablet DR image
Salamax Tablet DR image

Product introduction

Salamax Tablet DR may be taken with or without food. Take it regularly and at the same time each day to get the maximum benefit from it. Keep taking it as recommended by your doctor and complete the dose even if you feel better. Drinking plenty of water while taking it can help prevent kidney issues, including kidney stones.


Common side effects of Salamax Tablet DR include nausea, headache, vomiting, and gastrointestinal discomfort. You should consult with your doctor if any of these side effects do not resolve with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.


To ensure Salamax Tablet DR is safe for you, let your doctor know if you have any heart, kidney, or liver problems. Additionally, inform your doctor about all other medications you are currently taking. Your doctor may recommend regular blood tests to check your kidney and liver functions and blood components. Pregnant and breastfeeding mothers should seek medical advice before using this medicine.

Benefits of Salamax Tablet DR

Treatment of Rheumatoid arthritis
In individuals with rheumatoid arthritis, Salamax Tablet DR helps slow joint damage and reduce pain and swelling. It also helps improve mobility and makes daily activities easier by decreasing joint inflammation.
Treatment of Psoriatic arthritis
Psoriatic arthritis (PsA) is a type of inflammatory arthritis that affects some individuals with psoriasis, causing joint pain, swelling, and stiffness alongside skin symptoms. Salamax Tablet DR has anti-inflammatory properties that help reduce joint pain, swelling, and stiffness. This medicine can also slow down the progression of joint damage associated with PsA. Additionally, it can help improve skin symptoms in individuals with both psoriasis and arthritis.
Treatment of Ulcerative colitis
Ulcerative colitis is a disease of the large intestine (colon) and rectum in which the lining of the bowel becomes red and swollen. This can lead to bleeding, frequent diarrhea and abdominal pain. It relieves these symptoms and also helps you to stay well by preventing them from coming back. You should drink plenty of fluids while taking on treatment with this medicine to make sure you stay hydrated.
Treatment of Crohn’s disease
Crohn's disease is a chronic inflammatory bowel disease (IBD) that affects the digestive tract. Salamax Tablet DR helps reduce inflammation in the digestive tract, which can relieve symptoms of Crohn’s disease like diarrhea, stomach pain, and fatigue. Controlling inflammation also helps prevent flare-ups and improve overall gut health.
Treatment of Ankylosing spondylitis
Ankylosing spondylitis is a rare type of arthritis that affects the spine or larger joints. It usually starts in your lower back and can spread up to your neck or damage joints in other parts of your body. Salamax Tablet DR helps reduce pain, stiffness and swelling in your spine and joints. It helps improve flexibility and prevents disease progression. This will help you lead a better and active life.

Side effects of Salamax Tablet DR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Salamax
  • Gastrointestinal discomfort
  • Headache
  • Nausea
  • Oligospermia (low sperm count)
  • Vomiting

How to use Salamax Tablet DR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Salamax Tablet DR is to be taken with food.

How Salamax Tablet DR works

Salamax Tablet DR is a Disease Modifying Anti-Rheumatoid Drug (DMARD). It works by suppressing the overactivity of the immune system in autoimmune diseases and blocking the chemical messengers that cause inflammation (swelling).

All substitutes for Salamax Tablet DR

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Salamax Tablet DR may take 6-8 weeks to show effects. Continue taking it as prescribed.
  • Drink plenty of fluids while taking Salamax Tablet DR to help prevent kidney issues, including kidney stones.
  • Do not take Salamax Tablet DR if you have an allergy to sulfa drugs or aspirin.
  • Salamax Tablet DR may cause your skin, urine, saliva, and tears to appear orange or yellow in color. This is normal and not harmful.
  • Regular blood tests are necessary while taking this medicine to monitor liver function, kidney function, and blood component levels.
  • Do not stop taking the medication suddenly without talking to your doctor.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Salamax Tablet DR.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Salamax Tablet DR is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Salamax Tablet DR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

SAFE
Salamax Tablet DR does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Salamax Tablet DR should be used with caution in patients with kidney disease. Dose adjustment of Salamax Tablet DR may be needed. Please consult your doctor.
Regular monitoring of kidney function tests is advisable while you are taking this medicine.
Liver

Liver

UNSAFE
Salamax Tablet DR is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

Interaction with drugs

Taking Salamax with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Darolutamide (Oral Route)

Darolutamide may raise blood levels of Sulfasalazine. Darolutamide may raise blood levels of Sulfasalazine.

Frequently asked questions

Salamax Tablet DR belongs to a group of medicines called anti-inflammatory agents. It is used to treat various inflammatory conditions such as Crohn’s disease, rheumatoid arthritis, ulcerative colitis, and psoriatic arthritis.
Salamax Tablet DR is neither a steroid nor a painkiller. It is an anti-inflammatory medicine. It is used to treat and manage ulcerative colitis and Crohn's disease, in which the intestines become inflamed (swelling of intestines). It is also used to treat rheumatoid arthritis (painful joint disease).
Salamax Tablet DR does not work right away. It takes about 6 to 12 weeks to deliver the full effect. You may start feeling better in 4 weeks after starting Salamax Tablet DR, but it can vary from person to person, and some of the patients may notice improvement after 3 months. Consumption of medicine should not be stopped without consulting your doctor.
If you can tolerate Salamax Tablet DR, which means the side effects do not bother you, then you have to continue Salamax Tablet DR till the disease remains in remission. It is better to take Salamax Tablet DR for the prescribed period.
Though it is uncommon, Salamax Tablet DR may affect your kidney function. Therefore, your kidney function must remain normal before you start taking Salamax Tablet DR. If your kidney functions become abnormal during the treatment, consult your doctor.
Your doctor will advise blood tests to check your blood cell counts and your kidney function before starting your treatment and regularly during treatment. The tests should also be done to measure substances produced by your liver, known as enzymes (liver function tests), and urine for protein and blood before you start treatment and at regular intervals.
Decreased sperm count and infertility have been reported in some males. These may disappear once the Salamax Tablet DR is discontinued.
You should avoid using Salamax Tablet DR with azathioprine since there are chances of a decrease in blood cell count, which can be a serious side effect.

Fact Box

Chemical Class

Aminosalicylic Acids Derivative

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Non-Biologic DMARDs (Disease Modifying Anti-Rheumatoid Drugs)
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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