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Darolutamide

Written By Dr. Lipika KhuranaReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:34 AM (UTC)

Darolutamide Uses

Darolutamide is used in the treatment of prostate cancer, polycystic ovarian syndrome (PCOS) and excessive hair growth.

How Darolutamide works

Darolutamide works by blocking the effects of male reproductive hormone (testosterone) to stop the growth and spread of cancer cells.

Common side effects of Darolutamide

Fatigue, Pain in extremity, Rash
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Expert advice for Darolutamide

  • To reduce nausea, take antinausea medications as prescribed by your doctor, and eat small, frequent meals. 
  • Eat foods that may help reduce diarrhea, and take adequate rest.
  • Avoid getting pregnant and use contraceptives during the treatment and for 1 week after your last dose of Darolutamide.
  • You may be at risk of infection, so try to avoid crowds or people with cold, and immediately report fever or any other signs of infection to your healthcare provider. 
  • You may feel fatigued or dizzy after the treatment with this medicine. Drive only if you are alert, and avoid driving or operating machinery if you feel dizzy.
  • You have been prescribed Darolutamide for the treatment of prostate cancer.
  • Take it with or without food, preferably at the same time every day.
  • Do not drive or do anything requiring concentration unless you know how Darolutamide affects you.
  • It may cause your skin to become light sensitive. Avoid direct exposure to excessive sunlight and use sunscreen when outdoors.
  • If you are diabetic, monitor your blood glucose regularly while taking Darolutamide.
  • Your doctor may want you to have regular blood tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • Do not stop taking the medication without talking to your doctor first.