Zrepag 2mg Tablet

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 19 Jan 2026 | 04:21 PM (IST)

Zrepag 2mg Tablet is used to lower blood sugar levels in adults with type 2 diabetes mellitus. It is usually prescribed along with other diabetes medicines to achieve adequate blood sugar control. It also prevents serious complications of diabetes like kidney damage and blindness.

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Repaglinide (2mg)

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General Information

Contains

Repaglinide (2mg)

Marketer

Daylon Healthcare

Storage

Store below 25°C

The content is shown in English

Product introduction

Zrepag 2mg Tablet is normally prescribed when diet and exercise alone or other medicines have not been enough to control your blood sugar level. It works best when taken before meals. The dose will depend on your condition, and blood sugar levels, but you should take it as advised by your doctor.

Take Zrepag 2mg Tablet regularly, at the same time each day, to get the most benefit and you should not stop unless your doctor recommends it. It is controlling your blood sugar levels and helping to prevent serious complications in the future. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.

The most common side effects of this medicine is hypoglycemia (low blood sugar levels). You can carry sugar or glucose candy to control low blood sugar levels. Other common side effects that may be seen while taking this medicine include abdominal pain, inflammation of sinus, joint pain, back pain, nausea, and diarrhea. Contact your doctor if the side effects worry you or if they do not go away.

Before taking this medicine, let your doctor know if you have ever had kidney disease, heart or pancreas problems, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines you are taking may interfere with it so make sure your doctor knows about all the other medicines you are taking. You may need regular tests such as kidney function and blood glucose levels to check that the medicine is working properly.

Uses of Zrepag Tablet

Treatment of Type 2 diabetes mellitus

Benefits of Zrepag Tablet

Treatment of Type 2 diabetes mellitus
Type 2 diabetes happens when the body cannot use insulin properly or does not make enough of it, leading to high blood sugar levels. Zrepag 2mg Tablet helps lower blood sugar by stimulating the pancreas to release more insulin after meals. This improves blood sugar control and reduces the risk of diabetes-related complications.

Side effects of Zrepag Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zrepag

Hypoglycemia (low blood glucose level)
Abdominal pain
Nausea
Sinus inflammation
Back pain
Upper respiratory tract infection
Headache
Diarrhea
Joint pain

How to use Zrepag Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zrepag 2mg Tablet is to be taken on an empty stomach.

How Zrepag Tablet works

Zrepag 2mg Tablet is an anti-diabetic medication. It increases the amount of insulin released by the pancreas which prevents blood glucose from rising very high after meals.

All substitutes for Zrepag 2mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

For best results, take Zrepag 2mg Tablet 15 to 30 minutes before a meal.
You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Zrepag 2mg Tablet
It may cause dizziness. Do not drive or do anything that requires mental focus until you know how Zrepag 2mg Tablet affects you.
It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
Monitor your blood sugar levels regularly while you are taking this medicine.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Zrepag 2mg Tablet. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Zrepag 2mg Tablet is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Zrepag 2mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

CAUTION

Zrepag 2mg Tablet may affect your driving ability if your blood sugar becomes too low or too high. Monitor your blood glucose and avoid driving if affected.

Kidney

CAUTION

Zrepag 2mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Zrepag 2mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Zrepag 2mg Tablet is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Zrepag with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Gemfibrozil (Oral Route)

Do not consume Repaglinide with Gemfibrozil. Gemfibrozil may raise blood levels of Repaglinide.

Severe

Disopyramide (Oral Route)

If concurrent use is essential, watch out for symptoms such as confusion, headache, nausea, dizziness or faintness and consult your doctor if you experience them.

Moderate

Mifepristone (Oral Route)

Watch out for symptoms of Repaglinide side effects such as headache, nausea, dizziness or weakness and consult your doctor if you experience them. Mifepristone may raise blood levels of Repaglinide.

Moderate

Clopidogrel (Oral Route)

Do not consume Clopidogrel with Repaglinide. If concurrent use is essential, your doctor may monitor your blood glucose levels frequently and adjust the dose of Repaglinide as per the observations. Clopidogrel may raise blood levels of Repaglinide.

Moderate

Asparaginase (Injection Route)

Your doctor may monitor your diabetic control closely and adjust the doses as per the observations.

Frequently asked questions

How long does Zrepag 2mg Tablet take to start working?

Zrepag 2mg Tablet starts working 30 minutes after it has been taken. After you take Zrepag 2mg Tablet, the insulin levels increase causing a decrease in the blood sugar levels. The effect usually lasts for 4 hours.

Can I take alcohol while I am taking Zrepag 2mg Tablet?

No, you should avoid alcohol while taking Zrepag 2mg Tablet since alcohol interferes with the working of Zrepag 2mg Tablet. You may experience signs and symptoms of low blood sugar levels which include weakness, shakiness, cold sweat, cool pale skin, rapid heartbeat, tremors, extreme hunger, dizziness, headache, and anxiety.

Can Zrepag 2mg Tablet be taken with other antidiabetic drugs?

Yes, it can be taken with other antidiabetic drugs but according to your doctor’s advice. But since all these drugs lower blood sugar levels, regular monitoring of blood sugar levels is recommended.

Can I continue to breastfeed while taking Zrepag 2mg Tablet?

No, you should not breastfeed your baby because if Zrepag 2mg Tablet passes in breast milk, your baby may experience low blood sugar levels which is harmful to your baby. Ask your doctor for advice.

Do I need to stop clopidogrel if I am taking Zrepag 2mg Tablet?

You should inform your doctor and take his advice. If you cannot avoid using clopidogrel with Zrepag 2mg Tablet, take 0.5 mg Zrepag 2mg Tablet before each meal. The total daily dose should not be more than 4 mg. Monitor your blood sugar levels more frequently.

Fact Box

Chemical Class

Phenylpiperidines

Habit Forming

Therapeutic Class

ANTI DIABETIC

Action Class

Meglitinides (Insulin Secretagogues)

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1257.
Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 740-41.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1206-207.
Repaglinide [Product Monograph]. Ontario, Canada: Novo Nordisk Canada Inc.; 2015. [Accessed 4 Oct. 2021] (online) Available from:
DailyMed. Repaglinide [Prescription Drug Label]. [Accessed 4 Oct. 2021] (online) Available from:
Repaglinide [Summary of Product Characteristics]. Debrecen, Hungary: Teva Pharmaceutical Works Private Limited Company; 2014. [Accessed 4 Oct. 2021] (online) Available from:
Milner Z, Akhondi H. Repaglinide. [Updated 2021 Jul 10]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan. Available from:
Repaglinide [Prescribing Information]. Princeton, NJ: Macleods Pharma USA, INC; 2023. [Accessed 25 Jul. 2023] (online) Available from:
Repaglinide [Prescribing Information]. Saddle Brook, NJ: Rising Pharma Holdings, Inc.; 2024. [Accessed 19 Jan. 2026] (online). Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Daylon Healthcare
Address: 715, Gold Crest business center, L.T road, Borivali-W, Mumbai 400092

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Zrepag 2mg Tablet

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Zrepag Tablet

Benefits of Zrepag Tablet

Side effects of Zrepag Tablet

How to use Zrepag Tablet

How Zrepag Tablet works

All substitutes for Zrepag 2mg Tablet

Eurepa 2 Tablet

Premeal 2mg Tablet

Mage 2mg Tablet

Q Repa 2mg Tablet

Mlrepa 2mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Gemfibrozil (Oral Route)

Disopyramide (Oral Route)

Mifepristone (Oral Route)

Clopidogrel (Oral Route)

Asparaginase (Injection Route)

Frequently asked questions

How long does Zrepag 2mg Tablet take to start working?

Can I take alcohol while I am taking Zrepag 2mg Tablet?

Can Zrepag 2mg Tablet be taken with other antidiabetic drugs?

Can I continue to breastfeed while taking Zrepag 2mg Tablet?

Do I need to stop clopidogrel if I am taking Zrepag 2mg Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests