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Fenfluramine is used for short term therapy to reduce weight in the management of exogenous obesity (obesity caused by overeating).

How it works

Fenfluramine is an anti-obesity agent that belongs to the class of drugs called anorectics. It works by increasing the levels of a chemical (serotonin) in the body which eventually suppresses the appetite.

Common side effects

Constipation, Drowsiness, Dry mouth, Altered taste, Vomiting, Diarrhoea


Expert advice

  • Always take fenfluramine before meals.
  • You will be regularly monitored for blood pressure while taking fenfluramine if you have high blood pressure.
  • Exercise caution if you have history of mental disorders.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.
  • Do not take if allergic to fenfluramine or any of its ingredients.
  • Do not take if suffering with severe hypertension and irregular heartbeats (arrhythmias). 
  • Do not take if having problems with drug or alcohol abuse, heart disease, or glaucoma (a condition that causes damage to your eye's optic nerve and gets worse over time).

Frequently asked questions


Q. Is fenfluramine still available?
Fenfluramine is no longer available due to its association with unusual heart valve findings.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)