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Last updated:
19 Feb 2020 | 06:47 PM (IST)
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Metolaz 5mg Tablet


Overview

Introduction

Metolaz 5mg Tablet is a type of diuretic (water pill) medicine. This medicine reduces excess fluid levels in the body and is used to treat edema (fluid overload) associated with heart, liver, kidney, or lung disease. It is also used in treatment of hypertension (high blood pressure).

Metolaz 5mg Tablet makes you lose excess water through urine. It may be used alone or in combination with other medicines. This medicine should be taken only during day time to avoid frequent urination at night. You must take this medicine in the dose and duration as advised by the doctor and never stop it abruptly without consulting the doctor.

Common side effects of this medicine include headache, nausea, and dizziness. Consult your doctor if these side effects bother you. Before taking this medicine, it is better to let your doctor know if you are suffering from any kidney or liver disease. Also, pregnant women and breastfeeding mothers should consult a doctor before taking it. You must inform the doctor about all the other medicines that you are taking apart from this medicine. Regular monitoring of kidney function and electrolytes is important while using this medicine.

Side effects of Metolaz Tablet

Common
  • Headache
  • Nausea
  • Increased blood uric acid
  • Decreased potassium level in blood
  • Glucose intolerance
  • Altered blood lipid level

How to use Metolaz Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metolaz 5mg Tablet is to be taken with food.

How Metolaz Tablet works

Metolaz 5mg Tablet is a thiazide diuretic. It lowers blood pressure and fluid retention in edema by removing the extra water and certain electrolytes from the body. Over time it also works by relaxing blood vessels and improving blood flow.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Metolaz 5mg Tablet.
Pregnancy
SAFE IF PRESCRIBED
Metolaz 5mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breastfeeding
SAFE IF PRESCRIBED
Metolaz 5mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Metolaz 5mg Tablet may cause side effects which could affect your ability to drive.
As Metolaz 5mg Tablet may cause drowsiness, dizziness, blurred vision, or lightheadedness and this may affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Metolaz 5mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Metolaz 5mg Tablet is recommended.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Metolaz 5mg Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Metolaz Tablet?

If you miss a dose of Metolaz 5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Metolaz 5mg Tablet
₹12.85/Tablet
₹10.02/Tablet
save 22%
Lazon 5mg Tablet
United Biotech Pvt Ltd
₹11.53/Tablet
save 10%
Rpmel 5mg Tablet
RPG Life Sciences Ltd
₹18.2/Tablet
42% costlier
Metoz 5 Tablet
Centaur Pharmaceuticals Pvt Ltd
₹21.52/Tablet
67% costlier
Zytanix 5 Tablet
Zydus Cadila
₹24.32/Tablet
89% costlier

Quick Tips

  • Take it in the morning with breakfast to avoid getting up at night to urinate.
  • It makes you feel dizzy. Avoid driving and attention requiring activity until you know how it affects you.
  • Avoid alcohol intake while taking Metolaz 5mg Tablet as it may increase the dizziness. 
  • It may cause a sudden drop of sodium level in blood. Avoid low sodium diet while you are taking this medication.
  • Monitor your blood pressure after starting Metolaz 5mg Tablet, and notify your doctor if it does not lower down.
  • Notify your doctor if you experience dizziness, tiredness, or muscle weakness that does not go away.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. 

Interaction with Drugs

Taking Metolaz with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Diadose, Abacus, Disorb
SERIOUS
Brand(s): Amom, Samlodon, Amodep
SERIOUS
Brand(s): Hospicin B, Amfocare, Amphocil
SERIOUS
Brand(s): Becoride
SERIOUS

Patient Concerns

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I am a patient of hypertension
Dr. Jyoti Kapoor Madan
Psychiatry
Hypertension is clinal condition of high blood pressure. Please see a physician.
Some times I had lot of hypertension
Dr. Jyoti Kapoor Madan
Psychiatry
Hypertension is clinically high blood pressure. Persistent high arterial blood pressure above 120/80 mm HG is termed as pre-hypertension or hypertension, but the point to be emphasized is that this rise in blood pressure is persistent. Transient increase in BP occurs in stress and anxiety and needs to be treated accordingly.
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Do you have any questions related to Metolaz 5mg Tablet ?

FAQs

Q. Is metolazone potassium sparing diuretic/ loop diuretic/ beta blocker/ steroid/narcotic?

Metolazone belongs to the group of medicines called quinazoline and thiazide-like diuretic and it is not potassium sparing diuretic/ loop diuretic/ beta blocker/ steroid/narcotic

Q. Is metolazone discontinued?

No, metolazone is not discontinued

Q. Is metolazone stronger than Lasix?

Metolazone and furosemide (Lasix) belongs to same category of drugs (diuretics), but their effect may vary upon individual response

Q. Can you take metolazone with Lasix?

Metolazone and furosemide (Lasix) may sometimes be prescribed, but these combinations can lead to dehydration and electrolyte abnormalities. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required

Q. Does metolazone contain sulfa?

Yes, it contains sulfa. Chemically it is called as 7-chloro-2-methyl-4-oxo-3-o-tolyl-1, 2, 3, 4-tetrahydroquinazoline-6-sulfonamide

Q. Does metolazone get you high/ deplete potassium?

Metolazone causing the above side effects is uncommon or rare. However consult your doctor if you experience any of these side effects

Q. Does metolazone appear in breast milk?

Yes, metolazone gets excreted in breast milk. Patient should follow the advice of the doctor regarding its use

Q. How long does metolazone take to work?

It depends upon disease condition and lot of other factors. Patient should follow the advice of the doctor regarding its use.

Q. Can I use Metolaz with Torasemide?

Both Metolaz and Torasemide are diuretics and both can lower the blood potassium levels (hypokalemia). When given together, hypokalemia can be severe, causing muscle pains or cramps, loss of appetite, weakness, dizziness, or confusion. Inform your doctor if you have these symptoms and you are taking both the drugs. Take foods rich in potassium like orange or other citrus fruit juices or take a potassium supplement.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Opie LH, Victor RG, Kaplan NM. Diuretics. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 103-104.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 903.
  3. Metolazone tablets. Rochester, New York: Celltech Pharmaceuticals, Inc.; 2001. [Accessed 19 Mar. 2019] (online) Available from:External Link
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Metolazone. [Updated 2019 Feb 7]. [Accessed 19 Feb. 2020] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:External Link
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