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Loperamide is used for diarrhoea

How it works

Loperamide decreases the perception of pain by blocking the transmission of pain signals to the brain.

Common side effects

Sedation, Sleepiness, Fatigue, Vomiting, Weakness, Drowsiness, Dehydration, Dizziness, Headache, Lightheadedness, Sweating, Anemia, Stomach pain, Dry mouth, Nausea, Edema, Constipation, Gastrointestinal discomfort

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Expert advice

  • Consult your doctor if you have diarrhea lasting for more than 48 hours.
  • Don't use if you have blood in your stool or it's dark or black in color.
  • The drug can make you dizzy or drowzy. Avoid driving or operating any heavy machinery when taking this drug.
  • Try to drink plenty of fluids. Having diarrhea can make you dehydrated.
  • Do not take loperamide if you are allergic to it.
  • Do not take this drug if you have blood in your stools or if your stools are dark or black in colour.
  • Do not take this drug if you are severly constipated.

Frequently asked questions



Is Loperamide safe?
Loperamide is relatively safe if used as recommended. In case of any side effects, consult your doctor


What is loperamide/Imodium/Eldoper used for?
Loperamide/Imodium/Eldoper is used for treating short-term or long-term diarrhea, with or without any associated disease


Can it be used for IBS?
It may be used in few cases of IBS but please consult your doctor before its use

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Can I take loperamide with antibiotics, paracetamol, ibuprofen, omeprazole, ciprofloxacin, desmopressin, ritonavir, quinidine or cotrimoxazole?
Loperamide may be taken simultaneously with antibiotics, paracetamol, ibuprofen, omiprazole or ciprofloxacin. Loperamide might interact with desmopressin, ritonavir, quinidine or cotrimoxazole. Please consult your doctor before use


Does loperamide help in opiate withdrawal?
Loperamide is used in higher doses as a part of opiate withdrawal process. However, do consult your doctor regarding the same


Is loperamide addictive?
No. Loperamide is a safe and non-addictive anti-diarrheal drug


Is it banned or available as over-the-counter drug?
It is not banned but available over the counter in India


Can loperamide/ Impodium be used for stomach cramps, nausea, stomach flu, rota virus diarrhea and gas?
Loperamide may benefit few cases of stomach cramps or nausea associated with diarrhea. It is sometimes used for stomach flu, rota virus diarrhea. It is not used for gas. Please consult your doctor before taking the drug.

Content on this page was last updated on 13 February, 2017, by Dr. Varun Gupta (MD Pharmacology)