Dr. Betina Chandolia
Tata 1mg | Health Content Editor
4 Years Experience
Dr. Betina is a Health Content Editor with 1mg. She completed her BDS from Swami Devi Dyal Hospital and Dental College. Following which she completed her MDS from M.M. College of Dental Sciences and Research. Dr. Betina holds a Postgraduate Diploma in Hospital and Health Management from NIMS University, Jaipur and has a Postgraduate Certificate in Cyber Law from IGNOU. Before becoming a part of 1mg, Dr. Betina worked as an Assistant Professor cum OSD Dean cum Assistant Director with NIMS University for 4 years. Dr. Chandolia received Best Paper Award at International Symposium for Dental, Medical & Allied Sciences from NIMS University. She is a medical content writing specialist. She is a member of the International Association of Oral and Maxillofacial Pathology and Indian Association of Oral and Maxillofacial Pathology.
Qualifications and Experience
Writing in the Sciences | Stanford University | 2018 - 2018
The Fundamentals of Digital Marketing | Google Digital Garage | 2019 - 2019
Google Analytics for Beginners | Google Analytics Academy | 2019 - 2019
Advanced Google Analytics | Google Analytics Academy | 2019 - 2019
Primary cavernous hemangioma of parotid
Haemangioma is a benign neoplasm of vascular phenotype. 65% of haemangiomas have been noted to occur in the head and neck and mainly salivary glands are affected. The parotid gland is the most common site with hemangiomas comprising of 0.4-0.6% of parotid gland tumors. Salivary gland haemagniomas in adults are of the cavernous type while infantile haemangiomas are of the capillary type. We present a case of cavernous haemangioma in left parotid region in of 39 year old male.
Central Giant Cell Granuloma With Aneurysmal Bone Cyst In A 28-year Male Patient: A Rare Concurrence
Central Giant Cell Granuloma (CGCG) is a benign tumor of jaw. As compared to males, females are more commonly affected. Mandible is the common site of occurrence. Aneurysmal bone cysts (ABCs) are cystic lesions which are expansile osteolytic blood-filled lesions. These are commonly seen in the mandible, and they also show gender-predilection towards females. Concurrence of both the lesions is rarely reported. The treatment of both CGCG and ABC depends upon the extent of the lesions as well as on their nature. Due to aggressive nature of the lesions, these usually cause disfigurement of the patients' face. Wide excision is the treatment modality for aggressive lesions to avoid recurrence. We present a case of 28-year male who showed CGCG along with ABC in the same lesion, a rare concurrence.
Mucoepidermoid Carcinoma in a 62-Year Female
The Mucoepidermoid Carcinoma is a tumor of salivary gland. It comprises <3% of all head and neck tumors. As suggested by its name, MEC comprises of mucus-producing, squamous and intermediate type cells. Majority of these arise in the parotid gland, rest arise within the minor salivary glands. In minor salivary glands, MEC is seen on palate followed by retromolar area, floor of the mouth, buccal mucosa, lips and tongue. In adults, it most commonly occurs during fifth and sixth decades of life.
Prognostic Potential of N-Cadherin in Oral Squamous Cell Carcinoma via Immunohistochemical Methods
Objective: To assess the prognostic potential for N-cadherin in oral squamous cell carcinoma and oral epithelial dysplasia. Study Design: A cross-sectional study, analytical study. Place and Duration of Study: Maharishi Markandeshwar College of Dental Science Research (MMCDSR), Ambala, India, from 2011 to 2014. Methodology: Immunohistochemistry was used to observe the N-cadherin expression in 100 cases having epithelium with normal oral mucosa, oral epithelial dysplastic lesions and oral squamous cell carcinoma (OSCC). For statistical significance, SPSS 13.0 was used to calculate the data by Mann-Whitney and Kruskal-Wallis tests. Results: In OSCC, N-cadherin expression was more evident than in oral epithelial dysplasia followed by the normal oral epithelium that did not show any dysplastic changes (p=0.001). Conversely, N-cadherin expression was not significant among the histological grade of OSCC. Conclusion: N-cadherin can be used as a potential biomarker for early diagnosis of OSCC. However, the N-cadherin expression did not show any correlation with the histological grade of OSCC.
Glandular Odontogenic Cyst
The glandular odontogenic cyst (GOC), though rare, has now become a well known entity. The frequency of GOC ranges from 0.012% to 1.3% of all jaw cysts and its worldwide prevalence is 0.17%. The GOC's microscopic features have been well documented, and are also included in the list of World Health Organization. We report a case of GOC presenting as a unilocular osteodestructive lesion of anterior mandible in a 28-year female. The diagnosis was made on the basis of characteristic histological findings.
Epithelial Mesenchymal Interactions
Epithelial Mesenchymal Interactions play an important role in the development of various tissues such as in Odontogenesis, Salivary gland development, Tumor formation and metastasis. Cells are comprised of epithelia and mesenchyme and the signaling which takes place between these two is known as epithelial mesenchymal interactions.
The diagnosis of cancer involves the analysis of tissue and cytology specimens obtained through several procedures, including surgical biopsy, endoscopic biopsy, core or aspirational needle biopsy, venipuncture, spinal tap, pleural or ascitic tap, scraping of tissue surfaces and collection of exfoliative cells from urine and sputum. A tumor marker is one which can be used at early stages of the cancer which indicates the likely presence of cancer or that provides the information about the likely future behavior of a cancer.