Information about Metolazone

Metolazone uses

Metolazone is used in fluid retention (edema), heart failure, increased blood pressure and kidney stone.

How metolazone works

Metolazone lowers the blood pressure and swelling by removing extra water and electrolytes from the body.

Common side effects of metolazone

Headache, Nausea, Increased blood uric acid, Decreased potassium level in blood, Glucose intolerance, Altered blood lipids.

Available Medicine for Metolazone

  • ₹106 to ₹207
    Zydus Cadila
    2 variant(s)
  • ₹36 to ₹163
    Centaur Pharmaceuticals Pvt Ltd
    3 variant(s)
  • ₹100 to ₹205
    Cipla Ltd
    2 variant(s)
  • ₹107 to ₹182
    RPG Life Sciences Ltd
    2 variant(s)
  • ₹62 to ₹104
    Intas Pharmaceuticals Ltd
    2 variant(s)
  • ₹66 to ₹116
    United Biotech Pvt Ltd
    2 variant(s)
  • ₹55 to ₹129
    Centaur Pharmaceuticals Pvt Ltd
    2 variant(s)
  • ₹50 to ₹108
    Micro Labs Ltd
    2 variant(s)
  • ₹105 to ₹225
    Torrent Pharmaceuticals Ltd
    2 variant(s)

Expert advice for Metolazone

  • Do not take metolazone tablets, if you are allergic (hypersensitive) to sulfa drugs, thiazides, any other medications, metolazone or any of the other ingredients of metolazone tablet.
  • Do not take metolazone, if you are unable to urinate; if you have precoma or are in a coma caused by severe liver disease; if you have kidney or liver problem.
  • Avoid using metolazone, if you are pregnant or breastfeeding.
  • Consult your doctor, if you have or ever had diabetes, gout, low blood sodium or potassium levels, systemic lupus erythematosus.
  • Avoid prolonged exposure to sunlight.
  • Do not drive or operate machinery after taking metolazone.

Frequently asked questions for Metolazone


Q. Is metolazone potassium sparing diuretic/ loop diuretic/ beta blocker/ steroid/narcotic?
Metolazone belongs to the group of medicines called quinazoline and thiazide-like diuretic and it is not potassium sparing diuretic/ loop diuretic/ beta blocker/ steroid/narcotic
Q. Is metolazone discontinued?
No, metolazone is not discontinued
Q. Is metolazone stronger than Lasix?
Metolazone and furosemide (Lasix) belongs to same category of drugs (diuretics), but their effect may vary upon individual response
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Q. Can you take metolazone with Lasix?
Metolazone and furosemide (Lasix) may sometimes be prescribed, but these combinations can lead to dehydration and electrolyte abnormalities. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required
Q. Does metolazone contain sulfa?
Yes, it contains sulfa. Chemically it is called as 7-chloro-2-methyl-4-oxo-3-o-tolyl-1, 2, 3, 4-tetrahydroquinazoline-6-sulfonamide
Q. Does metolazone get you high/ deplete potassium?
Metolazone causing the above side effects is uncommon or rare. However consult your doctor if you experience any of these side effects
Q. Does metolazone appear in breast milk?
Yes, metolazone gets excreted in breast milk. Patient should follow the advice of the doctor regarding its use
Q. How long does metolazone take to work?
It depends upon disease condition and lot of other factors. Patient should follow the advice of the doctor regarding its use.
Q. Can I use Metolazone with Torasemide?
Both Metolazone and Torasemide are diuretics and both can lower the blood potassium levels (hypokalemia). When given together, hypokalemia can be severe, causing muscle pains or cramps, loss of appetite, weakness, dizziness, or confusion. Inform your doctor if you have these symptoms and you are taking both the drugs. Take foods rich in potassium like orange or other citrus fruit juices or take a potassium supplement.

Content on this page was last updated on 23 June, 2017, by Dr. Varun Gupta (MD Pharmacology)