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Gliclazide is used to lower the blood sugar levels in type 2 diabetes mellitus when diet, physical exercise and weight reduction alone are not adequate. 

How it works

Gliclazide belongs to a blood sugar lowering group of medicines called sulfonylurea. Gliclazide increases the amount of insulin released by the pancreas, and thereby decreases the blood sugar level.

Common side effects

Nausea, Abdominal pain, Abnormal blood cell, Angioedema (swelling of deeper layers of skin), Blisters on skin, Skin peeling, Constipation, Decreased blood cell count, Diarrhoea, Decreased sugar level in blood, Indigestion, Rash, Visual impairment, Vomiting


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Expert advice

  • Do not chew the tablet, and swallow the whole tablet with a glass of water or non-alcoholic drink just before a meal.
  • Do not take gliclazide, if you have type 1 diabetes mellitus or have impaired consciousness due to severe diabetes, liver or kidney disease, or deficiency of an enzyme called glucose-6-phosphate dehydrogenase.
  • Do not take gliclazide if you are pregnant or breast-feeding.

Frequently asked questions


Q. Is gliclazide same or, better than metformin?
Gliclazide and metformin belong to different class of drugs and act but separate mechanism. No significant difference between gliclazide and metformin was reported in clinical studies as regards their ability to reduce blood sugar.
Q. Is gliclazide the same as glipizide?
No,gliclazide and glipizide belong to a class of drugs known as sulphonylureas.
Q. Is gliclazide a statin or, steroid?
No,gliclazide belongs to sulfonylurea category of antidiabetic drug class.
Q. What is Glizid M?
Glizid M is a combination product that contains gliclazide and metformin. Both drugs are used to lower blood glucose levels in adult with type 2 diabetes mellitus that is not controlled by diet and exercise alone.

Content on this page was last updated on 18 October, 2016, by Dr. Varun Gupta (MD Pharmacology)