HYDERGINE 1 MG TABLET

Codergocrine Mesylate (1mg)

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HYDERGINE 1 MG TABLET is a prescription medicine used in the treatment of stroke, head injury, Alzheimer's disease (a condition in which a person loses memory and ability to think, communicate, learn, and handle daily activities), dementia (memory loss) in Parkinson's disease and age related memory loss.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 15 Sep 2026 | 01:02 AM (IST)

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General Information

Contains

Codergocrine Mesylate (1mg)

Marketer

Novartis India Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

HYDERGINE 1 MG TABLET should be taken on an empty stomach. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor. Do not stop taking it suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects that may be seen with this medicine include blurred vision, slow heart rate, decreased blood pressure, flushing (sense of warmth in the face, ears, neck, and trunk), headache, nasal congestion, rash, and vomiting. However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you. HYDERGINE 1 MG TABLET also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you and do not take alcohol with it as it may worsen the dizziness.

Before taking this medicine, inform your doctor if you ever had any problems with your kidneys or if you have or ever had any seizures (epilepsy or fits). Your dose depends on your age and the condition you are being treated for. Always let your doctor know about all the medicines that you are taking before you start with your treatment. Please inform your doctor if you are pregnant, planning to conceive or breastfeeding, before using this medicine.

Uses of Hydergine Tablet

Benefits of Hydergine Tablet

Alzheimer's disease
Alzheimer’s disease is a progressive brain disorder that affects memory, thinking, and behavior. HYDERGINE 1 MG TABLET helps improve blood supply and nerve activity in the brain, which may slow mental decline and support better memory function. This can help patients maintain daily activities for longer.

Stroke
Stroke happens when blood flow to a part of the brain is blocked or reduced, causing brain cells to lose oxygen and get damaged. HYDERGINE 1 MG TABLET helps improve blood circulation in the brain, which may support recovery and reduce further damage. This can aid in regaining movement, speech, and memory after a stroke.

Dementia in Parkinson's disease
Dementia in Parkinson’s disease occurs when brain changes from Parkinson’s affect memory, thinking, and decision-making. HYDERGINE 1 MG TABLET improves brain blood flow and nerve function, which may support mental clarity and slow worsening of symptoms. This helps improve the quality of life in affected individuals.

Age related memory loss
Age-related memory loss occurs gradually as brain cells age, making it harder to remember things or process information quickly. HYDERGINE 1 MG TABLET promotes brain circulation and activity, which may help maintain memory and mental sharpness. This supports clearer thinking and daily independence in older adults.

Head injury
Head injury can damage brain tissues, leading to memory loss, confusion, headaches, and difficulty in thinking clearly. HYDERGINE 1 MG TABLET works to improve brain blood flow and nerve function, which may support healing and restore cognitive abilities. This helps in better recovery of mental functions after injury

Side effects of Hydergine Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Hydergine

Blurred vision
Slow heart rate
Decreased blood pressure
Dizziness
Flushing (sense of warmth in the face, ears, neck and trunk)
Headache
Nasal congestion (stuffy nose)
Rash
Vomiting

How to use Hydergine Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. HYDERGINE 1 MG TABLET is to be taken on an empty stomach.

How Hydergine Tablet works

Codergocrine belongs to a class of medications called as Ergot Alkaloid. It causes expansion of blood vessels and increase in oxygen utilization in the brain. It also controls the chemicals responsible for cognitive functions.

Quick tips

HYDERGINE 1 MG TABLET should be taken on an empty stomach.
It might make you feel dizzy. If this happens, avoid driving or operating on machinery.
HYDERGINE 1 MG TABLET can affect your heart rate and blood pressure. Monitor your blood pressure and heart rate regularly.
Do not stop taking the medication suddenly without talking to your doctor.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with HYDERGINE 1 MG TABLET. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of HYDERGINE 1 MG TABLET during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CAUTION

HYDERGINE 1 MG TABLET should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

CAUTION

HYDERGINE 1 MG TABLET may cause dizziness or weakness due to changes in blood pressure. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of HYDERGINE 1 MG TABLET in patients with kidney disease. Please consult your doctor.

Liver

CAUTION

HYDERGINE 1 MG TABLET should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Hydergine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Zolmitriptan (Oral Route)

Ensure a gap of At least 24 hrs between taking Zolmitriptan and Codergocrine Mesylate.

Severe

Rizatriptan (Oral Route)

Ensure a gap of At least 24 hrs between taking Rizatriptan and Codergocrine Mesylate.

Severe

Naratriptan (Oral Route)

Ensure a gap of At least 24 hrs between taking Naratriptan and Codergocrine Mesylate.

Severe

Sumatriptan (Injection Route)

Ensure a gap of At least 24 hrs between taking Sumatriptan and Codergocrine Mesylate.

Severe

Sumatriptan (Oral Route)

Ensure a gap of At least 24 hrs between taking Sumatriptan and Codergocrine Mesylate.

Frequently asked questions

What is HYDERGINE 1 MG TABLET used for?

HYDERGINE 1 MG TABLET is used to improve cognitive (mental) and self-care functioning in people with dementia (loss of memory) related to aging or conditions such as Alzheimer's disease.

How quickly does HYDERGINE 1 MG TABLET work?

You may see an improvement in your symptoms after 4-5 weeks. However this depends on your condition, response to treatment and dosage administered. For best results, keep using the medication as directed.

I am having trouble remembering to take my medications. Is there anything I can do to help me remember?

In order to avoid missing a dose, use a calendar, pillbox, alarm clock, or cell phone alert to help you remember to take your medication. You may also ask a family member a friend to remind you or check in with you to be sure you are taking your medication.

Can a person with a kidney problem be given HYDERGINE 1 MG TABLET?

Although there are no studies indicating that this medicine causes further kidney problems, it should not be administered if a person has severe kidney disease.

Fact Box

Chemical Class

Ergot alkaloids

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Nootropic Agents

Related lab tests

Activated Partial Thromboplastin Time

Complete Blood Count

Prothrombin Time

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Novartis India Ltd
Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India

Vendor Details

Country of origin: India

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Hydergine Tablet

Benefits of Hydergine Tablet

Side effects of Hydergine Tablet

How to use Hydergine Tablet

How Hydergine Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Zolmitriptan (Oral Route)

Rizatriptan (Oral Route)

Naratriptan (Oral Route)

Sumatriptan (Injection Route)

Sumatriptan (Oral Route)

Frequently asked questions

What is HYDERGINE 1 MG TABLET used for?

How quickly does HYDERGINE 1 MG TABLET work?

I am having trouble remembering to take my medications. Is there anything I can do to help me remember?

Can a person with a kidney problem be given HYDERGINE 1 MG TABLET?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Activated Partial Thromboplastin Time

Complete Blood Count

Prothrombin Time

References

User feedback

What are you using Hydergine Tablet for?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests