Medicine Overview of Duzono Tablet
Side Effects of Duzono are Nausea, Headache, Dryness in mouth, Sleepiness, Dizziness.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Duzono 30 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Duzono 30 mg Tablet works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance and stop the movement of pain signals in the brain.
In Depth Information on Duzono Tablet
You may have to wait for 2 to 4 weeks to get the full effect.
- If your doctor asks you to stop Duzono 30 mg Tablet, you should not discontinue it abruptly. Many patients tolerate decreasing 50% dose every 3 days however if the withdrawal symptoms emerge during tapering it would require more gradual tapering over few weeks.
- Inform your doctor if you have ever been diagnosed with any heart problems (heart attack, heart failure, slow or irregular heart rate).
- Inform your doctor if you have ever been diagnosed with kidney or liver problems.
It can cause a sensation of restlessness or an inability to sit or stand still. This is most likely to occur within the first few weeks of treatment. You should tell your doctor if this happens to you.
- It may be more effective in some patients with depression who fails to respond to selective serotonin receptor inhibitors (SSRI) e.g. Fluoxetine.
- Monitor blood pressure (BP) frequently.
Duzono Tablet related warnings
Duzono 30 mg Tablet may cause excessive drowsiness and calmness with alcohol.
WEIGH RISKS VS BENEFITS
Duzono 30 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Duzono 30 mg Tablet is probably unsafe to use during lactation.
Limited human data suggest that the drug could represent a significant risk to the baby.
Duzono 30 mg Tablet may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.
Duzono 30 mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Duzono 30 mg Tablet may be needed. Please consult your doctor.
Dose adjustment is not recommended in patients with mild and moderate kidney disease.
Duzono 30 mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
If you miss a dose of Duzono 30 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Questions Related to Duzono
sir, my self im very depressing while comparing me to others& i dont talk to much bcoz i feel im not in level to talk with them & feel me about myself everyday about my negetativity.this type thinking stressess me very much how can i come from this type of stress?? i feel this is b.coz my weight & height at the age of 21 im right sir??
Dr. Jyoti Kapoor Madan
If you let your confidence down, you will develop helplessness ehic leads to depression. Instead of worrying about your weight, take action. Seek professional help. If you feel unmotivated, meet a psychiatrist, its neither too early nor too late for professional advice.
Sir i m suffering from mindly disturbance last 8 days because i have fail in love . Now i dont get to sleep. Only 2-3 hrs sleeping please help me. Im in more depression
Dr. Mehtab Baig
Think one mantra ,,,,,duniya jaye bhad me ,,,,, if u don't you takes always on medicine plz ignore all your memories with your ex And deleted
Doctor i m suffering from a major depression disoder i went to a psychiatrist 2 days back she prescribed tab paxidep cr 25mg, lithosun 300mg along with epitril 1mg for sleep purpose but still i m not getting sleep could you let me know that what is my rootcause & i would be on balance
Dr. Varun Mehta
Dear PATIENT are many causes of depression ranging from genetics to socialDifficulty in falling asleep is one of the symptoms of depressionThe medications take time to act and you should wait for atleast 7-10 days for observable effect to take place
I m in depression as I m not getting any job. Parents r forcing me for marriage bt i want to do something in my life nd now I m feeling like hell. What to do?
Dr. Jyoti Kapoor Madan
Dealing with Depression- Assess your thinking pattern. Become aware of negative thought patterns. Decide to trash negative thoughts and replace them by positive thoughts. Pursue hobbies that make you happy. Manage time by making a schedule that includes physical exercises and De stress routines. Communicate your thoughts to people you are comfortable with. Accept your limitations and work on them if possible, no one is born perfect and we don't need to be perfect, we need to be adaptive.
Diet control iam suffering from dipression and blood prassur
Dr. Waseem Mirza
Diet has no major role in depression. Just take your anti depressant medications regularly and follow up with your doctor periodically as advisedFor high bp, Take salt restricted diet, Avoid fatty foods. Walk daily for 30 mins
Hello sir i have taking the tablet of depression from three month this desease come out from dengue now i have taking ventab 25 mg proponol 10 mg and clozepam . 50mg but when i get off it again i feel anxient and sad. I feel freqeunt in mind only when i miss one or two days dose. I wanted to know that we will i stop these medicine i also wanted to get pregnant but due to this tablets i miss this chance sir please help me when will i conceive because have no baby and wanted to plan for this
Dr. Sunil Sekhri
you have been diagnosed with depression as told by you. It is a treatable condition. your re already undergoing medical therapy and you consult your Doctor to add Psychotherapy but this decision has to be made by your treating doctor
I feel like tired and not Intrested in work if I go to work my mind won't be constant it swings itseems like all new my heart beat get faster feel like difficult to breath
Dr. Ambrish Dharmadhikari
It seems you might be suffering from depression. Please search internet for self help CBT" and use those techniques for your help. Along with this please continue medications and follow up regularly with your psychiatrist."
Frequently asked questions about Duzono Tablet
Q. Is Duzono a non-steroidal anti-inflammatory drug (NSAID)?
No. Duzono is not a non-steroidal anti-inflammatory drug (NSAID). It belongs to the anti-depressant class of drugs, more specifically SNRI (Serotonin-Norepinephrine Reuptake Inhibitor). It works by increasing the levels of chemical messengers (serotonin and noradrenaline) in the nervous system.
No. Duzono is not a steroid. It belongs to the anti-depressant class of drugs, more specifically SNRI (Serotonin-Norepinephrine Reuptake Inhibitor). It works by increasing the levels of chemical messengers (serotonin and noradrenaline) in the nervous system.
Q. Is Duzono a blood thinner?
No. Duzono is not a blood thinner. Blood thinners prevent the formation of harmful blood clots.
Q. Is Duzono a stimulant?
No. Duzono is not a stimulant. Stimulants are the medicines which activate the central nervous system.
Q. Is Duzono a pain killer?
No. Duzono is not a classical painkiller e.g. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs).Duloxetine is used for the treatment of chronic pain conditions like neuropathic pain, diabetic neuropathy or fibromyalgia.
Q. Is Duzono a tricyclic antidepressant (TCA)?
No. Duzono is not a tricyclic antidepressant (TCA). It belongs to a class of anti-depressants called SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors).
Q. Is Duzono a benzodiazepine?
No. Duzono is not a benzodiazepine. It belongs to a class of anti-depressants called SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors). Benzodiazepines belong to the sedative-hypnotic class of drugs and include agents like diazepam, lorazepam, alprazolam etc.
No. Duzono is not a narcotic. It means it does not have habit-forming potential. Narcotics are the substance which can cause addiction and dependence.
Q. Is Duzono a psychotropic?
Yes. A psychotropic is a medicine that affects mind, emotions, and behaviour. Duzono, being an anti-depressant agent reduces the symptoms of depression and is a psychotropic agent.
Q. Can I take Duzono if I have Hepatitis C virus infection?
Duzono should be used with caution in patients with Hepatitis C virus infection. Cases of liver injury, including severe elevations of liver enzymes (>10-times upper limit of normal), hepatitis, and jaundice have been reported with Duzono. Taking Duzono increases the risk of liver toxicity and fatty liver in Hepatitis C virus-infected patients.<br>
Q. What is the peak plasma concentration [Cmax] of Duzono?
The maximum plasma concentration [Cmax] of Duzono is 6 hours post oral dose. Food taken with Duzono may delay the time to reach the peak plasma concentration from 6 to 10 hours. This may marginally decrease the extent of absorption (approximately 11%).
Q. Can I take Duzono with Vitamin D?
Yes. Duzonocan be taken with vitamin D. It does not have any known interaction with Vitamin D.
Q. What is half life of Duzono?
The elimination half-life of Duzono ranges from 8 to 17 hours (mean 12 hours).
Q. Which is better in depression, Duzono or fluoxetine?
Fluoxetine has not been found to be different in either tolerability or efficacy when compared with Duzono in major depression. Duzono is good for treating depression, anxiety and may help with chronic pain.
Q. Which is better Duzono vs sertraline?
Duzono and sertraline are found to be equally effective in the treatment of Major Depressive Disorder (MDD). Certain symptoms like agitation and anxiety are reduced better by sertraline. Duzono has been found to be better than sertraline for neuropathic pain.
Q. Which is better for chronic pain, Duzono or pregabalin?
In patients with fibromyalgia Duzono is found to be better than pregabalin in reducing depressed mood. Pregabalin is better in reducing fatigue. Duzono and pregabalin generally provide equally comparable pain relieving efficacy in the treatment of diabetic peripheral neuropathic pain (DPNP).
Q. Which is better Duzono or fluoxetine?
Duzono has been found to be better for the treatment of chronic pain than Fluoxetine. Fluoxetine is good for treating depression and anxiety.
Q. Which is better for depression, Duzono or mirtazapine?
Currently, there is not enough information to firmly recommend one antidepressant over another. However, both these drugs have been found to be safe and efficacious in the treatment of depression.
Q. Which is better for depression, Duzono or venlafaxine?
Currently, there is not enough information to firmly recommend one antidepressant over another. Many doctors favour Duzono over venlafaxine when pain conditions coexist with depression.
Q. Is Duzono a barbiturate?
No. Duzono is not a barbiturate. Barbiturates belong to the Sedative-Hypnotic class of drugs and are likely to have abuse potential.
Duzono can cause difficulty in sleep (insomnia). Hence, it is advised to be taken in the morning than at night.
Q. When does Duzono start working?
Usually, the action of Duzono takes about three to four weeks to appear. Do not discontinue the therapy in between, thinking that it is not effective.
Q. How much dose of Duzono can produce overdose?
Overdose can occur at a doses as low as 1000 mg. Signs and symptoms of overdose (duloxetine alone or in combination with other medicinal products) included somnolence, coma, serotonin syndrome, seizures, vomiting and tachycardia.
Q. How does Duzono work in urinary incontinence?
Duzono is thought to work by interfering with certain chemicals (called serotonin and noradrenaline) that are used within the nerves that send messages to your pelvic floor muscles. This helps the muscles around the bladder outlet to contract more strongly, and this in turn controls the flow of urine and helps to prevent any leakage.
Q. Can I take Duzono with amitriptyline?
It is better to avoid Duzono and amitriptyline together. It can increase the risk of a serious condition called the serotonin syndrome, with symptoms such as confusion, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea.
Q. Can I take Duzono with sertraline?
It is better to avoid Duzono and sertraline together. It can increase the risk of a serious condition called the serotonin syndrome, with symptoms such as confusion, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea.
Q. Can I take Duzono with tramadol?
Duzono and tramadol together can increase the risk of a serious condition called the serotonin syndrome, with symptoms such as confusion, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Please inform your doctor if you are taking any of these medicines before coming to him.
Q. Can I take Duzono with bupropion?
Bupropion can cause inhibition of metabolism of Duzono in the body, resulting in toxic effects of Duloxetine. The concomitant use of these two drugs can result in seizures. Mention it to your doctor if you are taking any of these medications from before.
Q. Which is better in diabetic neuropathy, duloxetine or pregabalin?
In patients with fibromyalgia, Duzono is found to be better than pregabalin in reducing depressed mood. Pregabalin is better in reducing fatigue. Duzono and pregabalin generally provide equally comparable pain relieving efficacy in the treatment of diabetic peripheral neuropathic pain (DPNP).
Q. Can Duzono get me high?
No. Duzono does not cause a high. It does not create a feeling of euphoria and has no recreational potential.
Q. Can I use Duzono for arthritis?
Duzono is not approved for the treatment of arthritis. It is used in the treatment of depression, anxiety disorder, diabetic nerve disease, neuropathic pain and overactive urinary bladder.
Q. Can I use Duzono for sciatica?
No, Duzono is not approved for the treatment of sciatica. It is used in the treatment of depression, anxiety disorder, diabetic nerve disease, neuropathic pain and overactive urinary bladder.
Q. Can I use Duzono for obsessive-compulsive disorder (OCD)?
Obsessive-compulsive disorder (OCD) is a type anxiety disorder. It is approved for the treatment of obsessive-compulsive disorder. Research studies suggest that Duzono may provide a significant reduction in symptoms for patients with obsessive-compulsive disorder.
Q. Can I use Duzono for hot flashes?
No. Duzono is not approved for use in hot flashes. It may be used in the treatment of depression in postmenopausal women suffering from menopausal vasomotor symptoms (hot flashes, night sweats) and insomnia.
Q. Can I use Duzono for headaches?
No, Duloxetine is not approved for use in headaches. It is used in the treatment of depression, anxiety disorder, diabetic nerve disease, neuropathic pain and overactive urinary bladder.
Q. Can I use Duzono for a migraine?
No. Duzono is not approved for use in a migraine. It is used in the treatment of depression, anxiety disorder, diabetic nerve disease, neuropathic pain and overactive urinary bladder.
Q. Can I use Duzono for chronic pain?
Duzono is approved for the treatment of chronic pain states including neuropathic pain (nerve pain) associated with Diabetes Mellitus and fibromyalgia.
Q. Can I use Duzono for nerve pain?
Yes. Duzono is approved for use in nerve pain or neuropathic pain conditions, most commonly seen in patients suffering from Diabetes Mellitus.
Q. Can Duzono raise blood sugar levels?
No. Duzono may affect blood sugar levels. If you are diabetic and notice a change in the results of your blood or urine sugar tests, check with your doctor.
Severely interacts with other drugs like
Taking Duzono with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Medicines with composition Thioridazine: R Zin, Zina, Thiolite
Medicines with composition Citalopram: Vocita, Celexa
Medicines with composition Paroxetine: Leparox, Prx, Paromec, Madotine, Parolyst, Parox, Baxidep, Psypro, Proxzen, Parotina
Medicines with composition Fluvoxamine: Boxamine, Voxinix, Fluvox, Uvox
Medicines with composition Atomoxetine: Attera
Medicines with composition Lithium: Psycolith, Cartil, A Lith, Likon, Lidep, Cylith, Elith
Medicines with composition Escitalopram: Kopram, Ecit, Escnx, Esitopa, Madito, Citolex, Elcit, Escivi, Esetinol, Esmood
Medicines with composition Nelfinavir: Nel
Medicines with composition Sertraline: Zosert, Sernit, Taline, Biosert, Pifser, Yline, Mares, Serwal, Setalin, Setrakon
Medicines with composition Fluoxetine: Flotin, Fluxen, FT, Bydep, Afzot, Ulaxy, Flurix, Tune, Foxe, Zotin
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