Dutidep 20mg Tablet

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 25 Nov 2025 | 03:05 PM (IST)

Dutidep 20mg Tablet is used in the treatment of depression, anxiety disorder, diabetic nerve pain, fibromyalgia (a condition in which there are generalized pain and tenderness in the body), neuropathic pain, and stress urinary incontinence.

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Dutidep 20mg Tablet

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Dutex 20mg Tablet

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Duloxetine (20mg)

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General Information

Contains

Duloxetine (20mg)

Marketer

Green Bract Lifesciences

Storage

Store below 30°C

The content is shown in English

Product introduction

Dutidep 20mg Tablet works by increasing the level of chemical messengers (serotonin and noradrenaline) in the brain that have a calming effect on the brain and relax the nerves, thus treating your illness. It may be taken with or without food. It is advised to take this medicine at a fixed time each day to maintain a consistent level in the blood. If you miss any doses, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly as it may worsen your symptoms.

Some common side effects of this medicine include nausea, headache, decreased libido, abnormal dreams, blurred vision, and dry mouth. It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. However, these side effects are temporary and usually resolve on their own in some time. Please consult your doctor if these do not subside or bother you.

Before taking Dutidep 20mg Tablet, inform your doctor if you have any problems with your kidneys, heart, liver, or have a history of seizures (epilepsy or fits). Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or if you have any suicidal thoughts.

Uses of Dutidep Tablet

Diabetic nerve pain
Depression
Anxiety disorder
Neuropathic pain
Overactive bladder (OAB)
Fibromyalgia
Treatment of Stress urinary incontinence

Benefits of Dutidep Tablet

Treatment of Stress urinary incontinence
Stress urinary incontinence refers to the loss of urine without conscious intention. It may occur due to a disturbed state of mind and thoughts. Dutidep 20mg Tablet helps in increasing the activity of those nerves in the brain that control muscles in our bladder that are responsible for passing urine. This helps in improving bladder control.

Side effects of Dutidep Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dutidep

Nausea
Headache
Dryness in mouth
Sleepiness
Dizziness
Blurred vision
Decreased libido
Abnormal dreams

How to use Dutidep Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dutidep 20mg Tablet may be taken with or without food.

How Dutidep Tablet works

Dutidep 20mg Tablet works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance and stop the movement of pain signals in the brain.

All substitutes for Dutidep 20mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Dutidep 20mg Tablet helps in treating depression and anxiety.
It may also be used to treat nerve pain from diabetes and some other forms of chronic pain.
It may take 2 to 4 weeks for Dutidep 20mg Tablet to start working. Keep taking it as prescribed.
It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking Dutidep 20mg Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
It may cause a sensation of restlessness, especially when you first start taking it. Inform your doctor if this happens to you.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Do not stop taking the medication suddenly without talking to your doctor.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Dutidep 20mg Tablet

Pregnancy

CONSULT YOUR DOCTOR

Dutidep 20mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Dutidep 20mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Dutidep 20mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Dutidep 20mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

Dutidep 20mg Tablet is unsafe to use in patients with liver disease and should be avoided.

Interaction with drugs

Taking Dutidep with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Moclobemide (Oral Route)

Do not consume Moclobemide with Duloxetine. If Moclobemide is essential, ensure a gap of at least 5 days after discontinuing Duloxetine. Please consult your doctor.

Life-threatening

Fluvoxamine (Oral Route)

Do not consume Duloxetine with Fluvoxamine. Fluvoxamine may raise blood levels of Duloxetine.

Life-threatening

Tapentadol (Nasal Route)

Avoid concurrent use unless your doctor considers it safe.

Life-threatening

Zolmitriptan (Nasal Route)

If concurrent use is essential, watch out for symptoms of serotonin syndrome such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may monitor and adjust the doses as per the observations.

Life-threatening

Selegiline (Oral Route)

Do not consume Selegiline with Duloxetine. If Selegiline is essential, ensure a gap of at least 2 weeks after discontinuing Duloxetine. Please consult your doctor.

Frequently asked questions

How long does Dutidep 20mg Tablet take to work?

In people with depression and anxiety, Dutidep 20mg Tablet mostly starts working within two weeks of treatment. However, you may take 2-4 weeks to feel better. Consult your doctor if you do not see any improvement after this time. In people with diabetic neuropathic pain, you may take a few weeks to feel better. Consult your doctor if you do not feel better after 2 months.

If I start feeling better, can I stop taking Dutidep 20mg Tablet?

No, you should not stop Dutidep 20mg Tablet suddenly and without consulting your doctor. In cases of depression and anxiety, if you have been feeling better for 6 months or more, your doctor may reduce your doses gradually. In case of pain and incontinence, if you are feeling better, continue taking it for the long term. Your doctor will keep monitoring your response to the medicine every few months.

Is Dutidep 20mg Tablet highly addictive?

No, Dutidep 20mg Tablet is not habit-forming (addictive). This means that it does not make you physically or psychologically dependent on it.

What will be the consequences if I stop taking Dutidep 20mg Tablet suddenly?

If you stop Dutidep 20mg Tablet suddenly, you may feel dizzy, tired, agitated or restless, anxious and irritated. You may also experience sleep disturbances (vivid dreams, nightmares, inability to sleep), nausea, vomiting, shaking, muscle pain, diarrhea, a piercing sensation (pins and needles) especially in the head, and excessive sweating or vertigo. Always consult your doctor before you stop taking Dutidep 20mg Tablet. Your doctor will reduce the dose gradually.

I am taking warfarin, does Dutidep 20mg Tablet interfere with warfarin? Is it safe to take both together?

You should be cautious if you are taking both Dutidep 20mg Tablet and warfarin since there is a risk of bleeding or you may experience petechiae or purpura.

Is Dutidep 20mg Tablet safe to use for long term?

Dutidep 20mg Tablet is safe to use for a long duration, provided you follow your doctor’s advice regarding the treatment.

I am a hypertensive patient. I have noticed that my blood pressure has increased after I started taking Dutidep 20mg Tablet. Is it because of Dutidep 20mg Tablet, what should be done?

Dutidep 20mg Tablet may cause an increase in blood pressure. Therefore, regular monitoring of blood pressure is required, especially during the first month of use. If your blood pressure increase is constant, consult your doctor. It may indicate that your Dutidep 20mg Tablet dose either needs to be reduced or discontinued gradually.

Fact Box

Chemical Class

Naphthalene derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)

Related lab tests

Glycosylated Hemoglobin

Urine Routine & Microscopy

References

Stahl SM, editor. Duloxetine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 219-24.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 442-43.
Duloxetine hydrochloride. Basingstoke, Hampshire: Eli Lilly and Company Limited; 2004 [revised 09 Nov. 2018]. [Accessed 23 Jan. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Duloxetine. [Updated 2020 Jan 20]. [Accessed 20 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Green Bract Lifesciences
Address: 1001, Phase 4 & 5, Model town, Bathinda, Punjab

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Dutidep 20mg Tablet

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Dutidep Tablet

Benefits of Dutidep Tablet

Side effects of Dutidep Tablet

How to use Dutidep Tablet

How Dutidep Tablet works

All substitutes for Dutidep 20mg Tablet

Dutex 20mg Tablet

Symbal 20 Tablet

Duvanta 20 Tablet

Duloxee 20 Tablet

DUlotin 20mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Moclobemide (Oral Route)

Fluvoxamine (Oral Route)

Tapentadol (Nasal Route)

Zolmitriptan (Nasal Route)

Selegiline (Oral Route)

Frequently asked questions

How long does Dutidep 20mg Tablet take to work?

If I start feeling better, can I stop taking Dutidep 20mg Tablet?

Is Dutidep 20mg Tablet highly addictive?

What will be the consequences if I stop taking Dutidep 20mg Tablet suddenly?

I am taking warfarin, does Dutidep 20mg Tablet interfere with warfarin? Is it safe to take both together?

Is Dutidep 20mg Tablet safe to use for long term?

I am a hypertensive patient. I have noticed that my blood pressure has increased after I started taking Dutidep 20mg Tablet. Is it because of Dutidep 20mg Tablet, what should be done?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Glycosylated Hemoglobin

Urine Routine & Microscopy

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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