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Dulodep 40mg Tablet

Prescription Required
Manufacturer
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)

Introduction

Dulodep 40mg Tablet is a prescription medicine used in the treatment of depression, anxiety disorder, diabetic nerve pain, fibromyalgia (a condition in which there are generalized pain and tenderness in the body), neuropathic pain and stress urinary incontinence.

Dulodep 40mg Tablet works by increasing the level of chemical messengers (serotonin and noradrenaline) in the brain that have a calming effect on the brain and relax the nerves, thus treating your illness. It may be taken with or without food. It is advised to take this medicine at a fixed time each day to maintain a consistent level in the blood. If you miss any doses, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly as it may worsen your symptoms.

Some common side effects of this medicine include nausea, headache, and dry mouth. It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. However, these side effects are temporary and usually resolve on their own in some time. Please consult your doctor if these do not subside or bother you.

Before taking Dulodep 40mg Tablet, inform your doctor if you have any problems with your kidneys, heart, liver, or have a history of seizures (epilepsy or fits). Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or if you have any suicidal thoughts.

Uses of Dulodep Tablet

Benefits of Dulodep Tablet

In Depression

Dulodep 40mg Tablet increases the levels of certain chemicals in the brain that improve our mood and behavior. This creates a feeling of wellbeing, relieves anxiety, reduces tension, helps you sleep better and increases your energy levels. It is an effective antidepressant but may cause drowsiness. You need to take it regularly as it is prescribed for it to be most effective and should not stop taking it suddenly, even if you feel better, as it may worsen your condition.

In Anxiety disorder

Dulodep 40mg Tablet stops your brain from releasing the chemicals that make you feel anxious so it can reduce the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness, tiredness, difficulty concentrating, feeling irritable and sleep problems that often come with Anxiety Disorder. It will therefore help you go about your daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping suddenly can cause serious problems.

In Diabetic nerve pain

High levels of blood sugar (glucose) levels in diabetic patients can cause damage to nerves and this can cause pain sensation. Dulodep 40mg Tablet helps reduce this damage by affecting chemicals in the brain called neurotransmitters. By relieving pain, it helps improve your quality of life.

In Fibromyalgia

Dulodep 40mg Tablet may also be used to treat pain in people with fibromyalgia. It reduces pain and also the mood changes, sleep problems, and tiredness that can be caused by the pain. It interferes with pain messages travelling through the brain. Taking this medicine regularly will have an impact on your overall quality of life. Keep taking the medicine until your doctor advises you to stop.

In Neuropathic pain

Dulodep 40mg Tablet is used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles or spinal cord injury. It interferes with pain signals that travel through the damaged nerves and the brain. Taking this medicine regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to take it regularly even if you feel it is not doing any good.

In Stress urinary incontinence

Stress urinary incontinence refers to the loss of urine without conscious intention. It may occur due to disturbed state of mind and thoughts. Dulodep 40mg Tablet helps in increasing the activity of those nerves in the brain that control muscles in our bladder that are responsible for passing urine. This helps in improving bladder control.

Side effects of Dulodep Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dulodep

  • Nausea
  • Headache
  • Dryness in mouth
  • Sleepiness
  • Dizziness

How to use Dulodep Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dulodep 40mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Dulodep Tablet works

Dulodep 40mg Tablet works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance and stop the movement of pain signals in the brain.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Dulodep 40mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Dulodep 40mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Dulodep 40mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Dulodep 40mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Dulodep 40mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Dulodep 40mg Tablet may be needed. Please consult your doctor.
Dose adjustment is not recommended in patients with mild and moderate kidney disease.
Liver
UNSAFE
Dulodep 40mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

What if you forget to take Dulodep Tablet?

If you miss a dose of Dulodep 40mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Dulodep 40mg Tablet
₹11.93/Tablet
Duloxee 40 Tablet
Talent India
₹12.7/Tablet
6% costlier
Combac 40 Tablet
Consern Pharma P Ltd
₹14.2/Tablet
19% costlier
Dulata 40mg Tablet
Healing Pharma India Pvt Ltd
₹14.2/Tablet
19% costlier
Duvanta 40 Tablet
Intas Pharmaceuticals Ltd
₹16.7/Tablet
40% costlier
Symbal 40 Tablet
Torrent Pharmaceuticals Ltd
₹18.93/Tablet
59% costlier

Quick Tips

  • Dulodep 40mg Tablet helps in treating depression and anxiety.
  • It may also  be used to treat nerve pain from diabetes and some other forms of chronic pain.
  • It may take 2 to 4 weeks for Dulodep 40mg Tablet to start working. Keep taking it as prescribed.
  • It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Dulodep 40mg Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
  • It may cause an increase in blood pressure, especially during the first month of treatment. Monitor your blood pressure regularly.
  • It may cause a sensation of restlessness, especially when you first start taking it. Inform your doctor if this happens to you.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Do not stop taking the medication suddenly without talking to your doctor.

Fact Box

Chemical Class
Naphthalene Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS

Interaction with Drugs

Taking Dulodep with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): R Zin, Zina, Thiolite
LIFE-THREATENING
Brand(s): Atazor, Atavir, Virataz
SERIOUS
Brand(s): Attera, Atomoxet, Atonext
SERIOUS
Brand(s): Vocita
SERIOUS

Patient Concerns

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Whenever i laugh very much my urine gets released
Dr. Praveen Pushkar
Urology
Consult urologist nearby. U r having stress urinary incontinence
Most of the times when I get excited or have orgasm I feel pain in my testis and around it .
Dr. Pranay Gandhi
Sexology
hi PATIENT neuropathic pain mostly. take tablet emanzen d 1 bd
arrow
Do you have any questions related to Dulodep 40mg Tablet ?

FAQs

Q. How long does Dulodep 40mg Tablet take to work?

In people with depression and anxiety, Dulodep 40mg Tablet mostly starts working within two weeks of treatment. However, you may take 2-4 weeks to feel better. Consult your doctor if you do not see any improvement after this time. In people with diabetic neuropathic pain, you may take a few weeks to feel better. Consult your doctor if you do not feel better after 2 months.

Q. If I start feeling better, can I stop taking Dulodep 40mg Tablet?

No, you should not stop Dulodep 40mg Tablet suddenly and without consulting your doctor. In cases of depression and anxiety, if you have been feeling better for 6 months or more, your doctor may reduce your doses gradually. In case of pain and incontinence, if you are feeling better, continue taking it for long term. Your doctor will keep monitoring your response to the medicine every few months.

Q. Is Dulodep 40mg Tablet highly addictive?

No, Dulodep 40mg Tablet is not habit-forming (addictive). This means that it does not make you physically or psychologically dependent on it.

Q. What will be the consequences if I stop taking Dulodep 40mg Tablet suddenly?

If you stop Dulodep 40mg Tablet suddenly, you may feel dizzy, tired, agitated or restless, anxious and irritated. You may also experience sleep disturbances (vivid dreams, nightmares, inability to sleep), nausea, vomiting, shaking, muscle pain, diarrhea, a piercing sensation (pins and needles) especially in the head and excessive sweating or vertigo. Always consult your doctor before you stop taking Dulodep 40mg Tablet. Your doctor will reduce the dose gradually.

Q. I am taking warfarin, does Dulodep 40mg Tablet interfere with warfarin? Is it safe to take both together?

You should be cautious if you are taking both Dulodep 40mg Tablet and warfarin since there is a risk of bleeding or you may experience petechiae or purpura.

Q. Is Dulodep 40mg Tablet safe to use for long term?

Dulodep 40mg Tablet is safe to use for a long duration, provided you follow your doctor’s advice regarding the treatment.

Q. I am a hypertensive patient. I have noticed that my blood pressure has increased after I started taking Dulodep 40mg Tablet. Is it because of Dulodep 40mg Tablet, what should be done?

Dulodep 40mg Tablet may cause an increase in blood pressure. Therefore, regular monitoring of blood pressure is required, especially during the first month of use. If your blood pressure increase is constant, consult your doctor. It may indicate that your Dulodep 40mg Tablet dose either needs to be reduced or discontinued gradually.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Stahl SM, editor. Duloxetine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 219-24.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 442-43.
  3. Duloxetine hydrochloride. Basingstoke, Hampshire: Eli Lilly and Company Limited; 2004 [revised 09 Nov. 2018]. [Accessed 23 Jan. 2019] (online) Available from:External Link
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Duloxetine. [Updated 2020 Jan 20]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

No. 10, 2nd Cross, Maravaneri, Salem - 636007, Tamil Nadu.
Expires on or after: January, 2021

A licensed vendor partner from your nearest location will deliver Dulodep 40mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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