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06 Aug 2019 | 04:11 PM (IST)
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Doxyril 25 mg Tablet


Doxyril Tablet side effects

  • Increased heart rate
  • Weight gain
  • Dryness in mouth
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Constipation
  • Difficulty in urination

How to use Doxyril Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Doxyril 25 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Doxyril Tablet works

Doxyril 25 mg Tablet increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

Doxyril Tablet related warnings

Doxyril 25 mg Tablet may cause excessive drowsiness with alcohol
Doxyril 25 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Doxyril 25 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
The baby should be monitored carefully for excessive sleepiness, and adequate weight gain.
Doxyril 25 mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Doxyril 25 mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Doxyril 25 mg Tablet is recommended.
However, talk to your doctor if you have any underlying kidney disease.
Doxyril 25 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Doxyril 25 mg Tablet may be needed. Please consult your doctor.

What if you miss a dose of Doxyril Tablet?

If you miss a dose of Doxyril 25 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Doxyril 25 mg Tablet
Doxedep 25mg Tablet
La Pharmaceuticals
18% costlier
Dox 25mg Tablet
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save 21%
Actipin 25mg Tablet
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Dermapin Tablet
Derma Prime
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Doxicar 25mg Tablet
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Expert Advice

  • Inform your doctor if you notice loss of consciousness,  agitation, reduced breathing rate, convulsions, muscle rigidity, and mouth dryness.
  • You may be asked for regular blood tests to monitor the blood cell count or level of sodium and sugar in the blood.
  • Inform your doctor if you notice behavioral changes, mood changes and suicidal thoughts while taking this medicine. 

Interaction with Drugs

Taking Doxyril with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Risure
Brand(s): Shinosun
Brand(s): Tremash
Brand(s): Zosert
Brand(s): Psycolith
Brand(s): Vlx
Brand(s): Eurolam
Brand(s): Panik
Brand(s): Leparox, Prx
Brand(s): Psycopan

Patient Concerns

Questions Related to Doxyril

Red pimples and khaj khujli my private part
Dr. Banashree Majumdar
Skin Specialist
Dear PATIENT A gel twice daily over face and tablet Atarax 25mg at night for itching
Stomach acidity after eating any food , loss of appetite insomnia also
Dr. Pranay Gandhi
u have psychiatric problem. irritable bowel syndrome take tablet amitryptaline 25mg hs for 14 days
Do you have any questions related to Doxyril 25 mg Tablet?


Q. Can I stop taking Doxyril abruptly?

No, you should always check with your doctor before you stop the treatment. Stopping the medicine abruptly may cause withdrawal effects. So, your doctor may reduce your dosage gradually before stopping the medicine completely. This helps to prevent a recurrence of the original symptoms of depression and reduce the chance of withdrawal effects.

Q. Does Doxyril cause withdrawal side effects?

Yes, stopping the use of Doxyril abruptly results in withdrawal symptoms which include insomnia (trouble falling asleep), irritability and excessive sweating. You should consult your doctor if you need to stop Doxyril who will advise gradual reduction of dose of Doxyril.

Q. When must Doxyril not be taken?

You should not take Doxyril if you have ever had an allergic reaction to antidepressants medicine (Doxyril), or any of the inactive ingredients of Doxyril. Avoid taking Doxyril if you have glaucoma (increased eye pressure), serious liver problems, are breastfeeding or are suffering from difficulty in passing urine. Do not take Doxyril if you are taking or have taken monoamine oxidase inhibitors (MAOIs) in the last two weeks or, suffer from mania (where you experience an abnormally elevated mood state) or are under 12 years of age.

Q. Can I use Doxyril for bipolar disorder?

Yes, Doxyril can be used in patients with bipolar disorder which means manic-depressive illness, in which there are periods of depression and periods of mood elevation.

Q. Can I drive while on Doxyril treatment?

Taking Doxyril may cause sleepiness, so you should avoid driving or working with machinery until the effect has worn off. Driving while taking Doxyril may cause sleep-driving. This refers to the instance of driving while not fully awake after taking a sleeping medicine, with loss of memory for the event and other serious side effects.

Q. What are the overdose symptoms of Doxyril?

Overdose of Doxyril can be mild or severe. Signs and symptoms of mild overdose include drowsiness, stupor, blurred vision and excessive dryness of the mouth. Severe overdose may cause loss of consciousness, reduced breathing rate, convulsions, low blood pressure, unusually fast heartbeat or palpitations. If you take too many capsules, contact your doctor immediately or seek emergency medical services in a nearby hospital.

Q. How long does it take for Doxyril to kick in?

It may take several weeks or longer for you to feel the full effect of Doxyril. Do not stop taking Doxyril without talking to your doctor, even if you feel well.

Q. Is Doxyril a sleeping pill?

Doxyril tablets are used for the treatment of insomnia (trouble falling asleep). It is especially helpful for people who have trouble staying asleep.

Q. Can I drink alcohol while on treatment with Doxyril?

No, you should not consume alcohol while taking Doxyril as alcohol can increase the severity of the sedative effects of Doxyril. This may also increase the risk of sleep-driving and other serious side effects.

Q. Is Doxyril addictive?

Generally Doxyril does not cause dependence and is therefore not addictive. But, you should not stop abruptly as it may cause temporary withdrawal symptoms.

Q. Can Doxyril cause suicidal thoughts?

Yes, Doxyril can cause suicidal thoughts. This is more common in people who have previously had thoughts about killing or harming themselves or if the person is a young adult less than 25 years who have a history of psychiatric conditions and was treated with an antidepressant. If you experience suicidal thoughts, contact your doctor or go to a hospital straight away. You may find it helpful to talk to a relative or close friend.

Q. Does Doxyril cause weight gain?

Doxyril may cause weight gain as well as loss of appetite, but it is not very common. Call your doctor if the weight gain or the loss of appetite is severe or does not go away.

Q. What is the best time to take Doxyril?

If you are taking Doxyril for insomnia, you should take it 30 minutes before bedtime and should confine your activities to those necessary to prepare for bed. Remember to take this medicine at the same time each day. If you are taking it for depression or anxiety, take it exactly as directed by your doctor.

Q. What are the side effects of Doxyril?

The side effects of Doxyril include nausea, vomiting, weakness or tiredness, dizziness, headache, hair loss, diarrhea, difficulty urinating, flushing and changes in appetite or weight. It may also cause increase in pupil size, dry mouth, mouth sores, changes in the way things taste, indigestion, constipation, excessive thirst and urination, ringing in your ears, changes in sex drive, swollen testicles, increased breast size, and milky discharge from nipples in females. It may make your skin more sensitive to sunlight, cause chills and excessive sweating.
Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
  1. Stahl SM, editor. Doxepin. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 211-17.
  2. Skidgel RA, Kaplan AP, Erdös EG. Histamine, Bradykinin, and Their Antagonists. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 923.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 430-31.
  4. Doxepin. San Diego: Somaxon Pharmaceuticals; 1969 [revised date]. [Accessed 22 Mar. 2019] (online) Available from:External Link
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:External Link
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Reliance Formulation Private Limited, 201-202, Anand Mangal-3, Rajnagar Club Road Ambabadi, Ahmedabad-380015, Gujarat, India
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