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19 Aug 2019 | 04:34 PM (IST)
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Birlotib 150 Tablet


Overview

Introduction of Birlotib Tablet

Birlotib 150 Tablet is used in the treatment of non-small cell lung cancer and pancreatic cancer.

Birlotib 150 Tablet should be taken in a dose as recommended by the doctor. You should continue to take it as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. Your doctor may advice for regular monitoring of liver function while your taking this medicine. It is advisable to avoid smoking while taking Birlotib 150 Tablet as it makes the medicine ineffective and requires dose adjustment.

Women who are undergoing treatment should use effective contraception method. It is important to avoid pregnancy during the treatment and for a month after completing the course of medicine. This medicine may make your skin more sensitive to sun, so it is better to use sunscreen and protective clothing when outdoors. Diarrhea may occur as its side effect, so drink plenty of fluids. But, you must inform doctor if it does not stop or you find blood in stools. In case you develop ulceration in mouth, changes in your vision, or breathing difficulties than it is better to inform the doctor.

Birlotib Tablet side effects

Common
  • Nausea
  • Vomiting
  • Fatigue
  • Abdominal pain
  • Edema (swelling)
  • Weight loss
  • Infection
  • Bone pain
  • Constipation
  • Diarrhea
  • Fever
  • Stomatitis (Inflammation of the mouth)
  • Rash
  • Shortness of breath
  • Muscle pain
  • Cough

How to use Birlotib Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Birlotib 150 Tablet is to be taken empty stomach.

How Birlotib Tablet works

Birlotib 150 Tablet is an anti-cancer medication. Epidermal growth factor receptors (EGFR) are expressed on the lung cancer cell surfaces that modulate their growth. This medicine works by binding the chemical messenger, EGFR, hence, inhibits the cancer signaling pathways mediated by EGFR. This is how it restricts further growth of the cancer cells.

Birlotib Tablet related warnings

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Birlotib 150 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Birlotib 150 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Lactation
CONSULT YOUR DOCTOR
Birlotib 150 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Birlotib 150 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Birlotib 150 Tablet is safe to use in patients with kidney disease. No dose adjustment of Birlotib 150 Tablet is recommended.
Use of this medicine is not advised in patients with severe kidney disease.
Liver
CAUTION
Birlotib 150 Tablet should be used with caution in patients with liver disease. Dose adjustment of Birlotib 150 Tablet may be needed. Please consult your doctor.
Limited information is available on the use of Birlotib 150 Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

What if you miss a dose of Birlotib Tablet?

If you miss a dose of Birlotib 150 Tablet, skip it and continue with your normal schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Birlotib 150 Tablet
₹89.18/Tablet
Erlotib 150mg Tablet
Intas Pharmaceuticals Ltd
₹297.52/Tablet
234% costlier
Erleva 150mg Tablet
Glenmark Pharmaceuticals Ltd
₹145.2/Tablet
63% costlier
Erlotirel 150mg Tablet
Reliance Life Sciences
₹213.33/Tablet
139% costlier
Erlotec 150mg Tablet
United Biotech Pvt Ltd
₹850/Tablet
853% costlier
TARCEVA 150MG TABLET
Roche Products India Pvt Ltd
₹4030/Tablet
4419% costlier

Expert Advice

  • Birlotib 150 Tablet helps treat non-small cell lung cancer that is locally advanced, or has spread to other areas of the body.
  • It should be taken 1 hour before or 2 hours after the meal.
  • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
  • It makes your skin sensitive towards sunlight. Apply sunscreen or wear protective clothing while going out.
  • It is advisable to avoid smoking while taking this medicine, as it makes the drug ineffective and requires dose adjustment.
  • Do not take it with medication lowering the stomach acid (such as antacids, H2 blockers including ranitidine), as it may affect the working of medicine.
  • Inform your doctor if you develop ulceration in your mouth, changes in your vision or if you experience a worsening cough, shortness of breath, or breathing difficulties while taking this medicine.
  • Your doctor may want you to have regular blood tests to monitor your liver function while you are having treatment with this medicine.
  • Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Patient Concerns

Questions Related to Birlotib

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What is the purpose of Chemotherepy given at the time of radiotherapy in ca lung small cell carcinoma
Dr. Vijay Sharnangat
Cancer Specialist
This is given to enhance the therapeutic effect of radiation therapy which is curative for small cell lung cancer.
My mother is pancreatic cancer patientSo give me a best treatment
Dr. Sanjay Singh Rai
Cancer Specialist
She need more testsTumor markers CA 19.9, CEA LEVEL, CA 125 LEVEL
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Do you have any questions related to Birlotib 150 Tablet?

User Feedback


FAQs

Q. How should Birlotib be taken?

Birlotib is a pill to be taken by mouth, once a day without food as prescribed by your doctor. It is important that you take Birlotib empty stomach, at least 1 hour before or 2 house after meals. It is advisable to take it the same time each day so that you remember when to take it.

Q. Is Birlotib a chemotherapy drug?

Birlotib is not a conventional chemotherapy medicine. Birlotib belongs to a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This in turn helps to slow or stop the spread of cancer cells.

Q. How long can I take Birlotib?

You need to take Birlotib every day, as long as your doctor prescribes it for you. The duration of treatment may vary from person to person.

Q. Does smoking interfere with Birlotib?

Yes, smoking can interfere with the working of Birlotib. It can decrease the effectiveness of the medicine to a great extent. Hence, it is advised to stop smoking before you start Birlotib. Your doctor will need to adjust the dose of Birlotib, if you keep on smoking or there is a change in the pattern of smoking.

Q. What should I do if I get a rash while taking Birlotib?

Rash is a common side effect of Birlotib but you should not stop taking Birlotib because of this. Consult your doctor who will suggest a treatment for it. Also, avoid sun-exposure, use a sunscreen and wear protective clothing.

Q. When can I plan pregnancy, if I am taking Birlotib?

Avoid pregnancy while being treated with Birlotib. If you are a woman of child-bearing age use effective contraception during treatment. Avoid pregnancy for at least 1 month after taking the last tablet.

Q. Does Birlotib affect eyes?

Birlotib commonly causes conjunctivitis and dry eyes. If you develop acute or worsening redness and pain in the eye, increased eye-watering, blurred vision and/or sensitivity to light, immediately inform the doctor as you may need urgent treatment.

Q. When should I call my doctor during treatment with Birlotib?

Inform the doctor if you experience sudden difficulty in breathing associated with cough or fever, severe or ongoing diarrhea, loss of appetite, nausea, and vomiting. Also, consult your doctor if you experience acute or worsening redness and pain in the eye, increased eye-watering, blurred vision and/or sensitivity to light. Let your doctor know in case you are taking a statin (medicine to control cholesterol) along with this medicine and experience unexplained muscle pain, tenderness, weakness, or cramps.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1735-36.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 954-55.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 489-90.
  4. Erlotinib. Seymour, Indiana: Schwarz Pharma Manufacturing; 2014 [revised May 2010]. [Accessed 23 Jan. 2019] (online) Available from:External Link
  5. U.S. National Library of Medicine. Erlotinib. [Accessed 26 Mar. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link
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