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Zyceva 150 Tablet

Erlotinib (150mg)

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Zyceva 150 Tablet is used in the treatment of non-small cell lung cancer and pancreatic cancer.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)

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General Information

Contains

Erlotinib (150mg)

Marketer

Zydus Cadila

Storage

Store below 30°C

The content is shown in English

Product introduction

Zyceva 150 Tablet should be taken on an empty stomach or should be taken one hour before or 2 hour after meal. You should continue to take it as long as your doctor advises it. The duration of treatment varies according to your needs and response to treatment. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, fatigue, rash, and weight loss. It may cause severe diarrhea, drink plenty of fluids or consult with your doctor if it bothers you. It makes you sensitive towards sunlight, hence wear protective clothing or use sunscreen while going out. In case you develop ulceration in mouth, changes in your vision, or breathing difficulties than it is better to inform the doctor. Your doctor may advise for regular monitoring of liver function while you are taking this medicine.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. It is advised to quit smoking while taking this medicine as it can affect the working of the medicine. If you have to take an antacid or any other medicine, take it at a gap of at least 2 hours after taking the cancer medicine.

Uses of Zyceva Tablet

Benefits of Zyceva Tablet

Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Zyceva 150 Tablet helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Zyceva Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zyceva

Abdominal pain
Bone pain
Breathlessness
Constipation
Cough
Diarrhea
Fatigue
Fever
Infection
Muscle pain
Nausea
Rash
Stomatitis (Inflammation of the mouth)
Vomiting
Weight loss

How to use Zyceva Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zyceva 150 Tablet is to be taken on an empty stomach.

How Zyceva Tablet works

Zyceva 150 Tablet is an anti-cancer medication. Epidermal growth factor receptors (EGFR) are expressed on the lung cancer cell surfaces that modulate their growth. This medicine works by binding the chemical messenger, EGFR, hence, inhibits the cancer signaling pathways mediated by EGFR. This is how it restricts further growth of the cancer cells.

All substitutes for Zyceva 150 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Zyceva 150 Tablet helps treat non-small cell lung cancer that is locally advanced, or has spread to other areas of the body.
It should be taken 1 hour before or 2 hours after the meal.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
It makes your skin sensitive towards sunlight. Apply sunscreen or wear protective clothing while going out.
It is advisable to avoid smoking while taking this medicine, as it makes the drug ineffective and requires dose adjustment.
Do not take it with medication lowering the stomach acid (such as antacids, H2 blockers including ranitidine), as it may affect the working of medicine.
Inform your doctor if you develop ulceration in your mouth, changes in your vision or if you experience a worsening cough, shortness of breath, or breathing difficulties while taking this medicine.
Your doctor may want you to have regular blood tests to monitor your liver function while you are having treatment with this medicine.
Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Zyceva 150 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Zyceva 150 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Zyceva 150 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Zyceva 150 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

SAFE IF PRESCRIBED

Zyceva 150 Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.
Use of this medicine is not advised in patients with severe kidney disease.

Liver

CAUTION

Zyceva 150 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Zyceva with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Vinorelbine (Injection Route)

Do not consume Vinorelbine with Erlotinib.

Severe

Dexlansoprazole (Oral Route)

Do not consume Erlotinib with Dexlansoprazole. Dexlansoprazole may reduce blood levels of Erlotinib.

Severe

Esomeprazole (Oral Route)

Do not consume Erlotinib with Esomeprazole. Esomeprazole may reduce blood levels of Erlotinib.

Severe

Esomeprazole (Injection Route)

Do not consume Erlotinib with Esomeprazole. Esomeprazole may reduce blood levels of Erlotinib.

Severe

Lansoprazole (Oral Route)

Do not consume Erlotinib with Lansoprazole. Lansoprazole may reduce blood levels of Erlotinib.

Frequently asked questions

How should Zyceva 150 Tablet be taken?

Zyceva 150 Tablet is a pill to be taken by mouth, once a day without food as prescribed by your doctor. It is important that you take Zyceva 150 Tablet empty stomach, at least 1 hour before or 2 house after meals. It is advisable to take it the same time each day so that you remember when to take it.

Is Zyceva 150 Tablet a chemotherapy drug?

Zyceva 150 Tablet is not a conventional chemotherapy medicine. Zyceva 150 Tablet belongs to a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This in turn helps to slow or stop the spread of cancer cells.

How long can I take Zyceva 150 Tablet?

You need to take Zyceva 150 Tablet every day, as long as your doctor prescribes it for you. The duration of treatment may vary from person to person.

Does smoking interfere with Zyceva 150 Tablet?

Yes, smoking can interfere with the working of Zyceva 150 Tablet. It can decrease the effectiveness of the medicine to a great extent. Hence, it is advised to stop smoking before you start Zyceva 150 Tablet. Your doctor will need to adjust the dose of Zyceva 150 Tablet, if you keep on smoking or there is a change in the pattern of smoking.

What should I do if I get a rash while taking Zyceva 150 Tablet?

Rash is a common side effect of Zyceva 150 Tablet but you should not stop taking Zyceva 150 Tablet because of this. Consult your doctor who will suggest a treatment for it. Also, avoid sun-exposure, use a sunscreen and wear protective clothing.

When can I plan pregnancy, if I am taking Zyceva 150 Tablet?

Avoid pregnancy while being treated with Zyceva 150 Tablet. If you are a woman of child-bearing age use effective contraception during treatment. Avoid pregnancy for at least 1 month after taking the last tablet.

Does Zyceva 150 Tablet affect eyes?

Zyceva 150 Tablet commonly causes conjunctivitis and dry eyes. If you develop acute or worsening redness and pain in the eye, increased eye-watering, blurred vision and/or sensitivity to light, immediately inform the doctor as you may need urgent treatment.

When should I call my doctor during treatment with Zyceva 150 Tablet?

Inform the doctor if you experience sudden difficulty in breathing associated with cough or fever, severe or ongoing diarrhea, loss of appetite, nausea, and vomiting. Also, consult your doctor if you experience acute or worsening redness and pain in the eye, increased eye-watering, blurred vision and/or sensitivity to light. Let your doctor know in case you are taking a statin (medicine to control cholesterol) along with this medicine and experience unexplained muscle pain, tenderness, weakness, or cramps.

Fact Box

Chemical Class

Quinazolinamines

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine Kinase Inhibitors (TKIs)

Related lab tests

Carcino Embryonic Antigen

References

Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1735-36.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 954-55.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 489-90.
Erlotinib. Seymour, Indiana: Schwarz Pharma Manufacturing; 2014 [revised May 2010]. [Accessed 23 Jan. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Erlotinib. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Erlotinib [Prescribing Information]. Seymour, IN: Schwarz Pharma Manufacturing; 2010. [Accessed 25 Jul. 2024] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zydus Cadila
Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Zyceva 150 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Zyceva 150 Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Zyceva Tablet

Benefits of Zyceva Tablet

Side effects of Zyceva Tablet

How to use Zyceva Tablet

How Zyceva Tablet works

All substitutes for Zyceva 150 Tablet

Erlonat 150 Tablet

Tarceva 150mg Tablet

Tyrokinin 150mg Tablet

Erleva 150mg Tablet

Erlokem 150mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Vinorelbine (Injection Route)

Dexlansoprazole (Oral Route)

Esomeprazole (Oral Route)

Esomeprazole (Injection Route)

Lansoprazole (Oral Route)

Frequently asked questions

How should Zyceva 150 Tablet be taken?

Is Zyceva 150 Tablet a chemotherapy drug?

How long can I take Zyceva 150 Tablet?

Does smoking interfere with Zyceva 150 Tablet?

What should I do if I get a rash while taking Zyceva 150 Tablet?

When can I plan pregnancy, if I am taking Zyceva 150 Tablet?

Does Zyceva 150 Tablet affect eyes?

When should I call my doctor during treatment with Zyceva 150 Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Carcino Embryonic Antigen

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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