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Erlonat 150 Tablet

Prescription Required

Overview

Introduction

Erlonat 150 Tablet is used in the treatment of non-small cell lung cancer and pancreatic cancer.

Erlonat 150 Tablet should be taken on an empty stomach or should be taken one hour before or 2 hour after meal.  You should continue to take it as long as your doctor advises it. The duration of treatment varies according to your needs and response to treatment. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, fatigue, rash, and weight loss. It may cause severe diarrhea, drink plenty of fluids or consult with your doctor if it bothers you. It makes you sensitive towards sunlight, hence wear protective clothing or use sunscreen while going out. In case you develop ulceration in mouth, changes in your vision, or breathing difficulties than it is better to inform the doctor. Your doctor may advise for regular monitoring of liver function while you are taking this medicine.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.  It is advised to quit smoking while taking this medicine as it can affect the working of the medicine. If you have to take an antacid or any other medicine, take it at a gap of at least 2 hours after taking the cancer medicine.

Side effects of Erlonat Tablet

Common
  • Abdominal pain
  • Bone pain
  • Breathlessness
  • Constipation
  • Cough
  • Diarrhea
  • Fatigue
  • Fever
  • Infection
  • Muscle pain
  • Nausea
  • Rash
  • Stomatitis (Inflammation of the mouth)
  • Vomiting
  • Weight loss

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Abdominal pain
    In most cases, this is mild enough to be treated at home. Try to rest and relax. Putting a heat pad or covered hot water bottle on your stomach may also help. Having a warm bath or shower can help you relax and relieve the pain. Drink plenty of clear fluids such as water and reduce your intake of coffee, tea, lemon juice or soda. Avoid alcohol and smoking as these can aggravate the pain. Eating slowly and having smaller and more frequent meals can also help. If the pain is severe, speak to your doctor. They may be able to guide you better.
  • Coping with Bone pain
    Try to keep your joints moving. Get some gentle exercise like walking or cycling. Using hot and cold treatments on the joints can help reduce pain temporarily. Concentrate on your breathing when you are in pain. Try to get enough sleep. Practice some relaxation techniques or mediation. Avoid smoking as it can worsen your condition. Losing weight can make a big difference to the amount of pain. Ask your doctor to recommend some suitable painkillers if the pain bothers you or does not go away.
  • Coping with Breathlessness
    Control your breaths by breathing in slowly through your nose and breathing out through your mouth. Sitting on a chair and leaning your chest slightly forward may also help. Increase the flow of air around you by opening windows or using a fan. Try to learn breathing techniques and do regular physical exercise. Wearing loose clothing around your waist and chest may also be helpful. Your breathing will usually return to normal within a few weeks of starting the medicine. Tell your doctor if your symptoms do not improve or get worse. Shortness of breath can also be a sign of an ongoing or worsening heart problem.
  • Coping with Constipation
    Try to eat foods which are high in fiber such as fresh fruits, vegetables and cereals to increase the bulk and consistency of bowel movements. Drink plenty of water or non-alcoholic drinks and stay hydrated to promote healthy digestion. Increasing physical activities such as walking, yoga and regular exercise can also be helpful. If your condition does not improve, you can ask your doctor to prescribe you laxative medicine.
  • Coping with Cough
    Get plenty of rest as exhausting or stressing out yourself could aggravate your condition. You should drink plenty of fluids as it will keep your throat moist and comfortable. Try taking steam inhalation. The moisture can ease your breathing and loosen mucus. You can consider sipping warm water or tea with honey and lemon. This will keep your nose and throat from being too dry. Using an air humidifier may also help. You can also gargle with salt water several times a day. See your doctor if your symptoms last longer than 3 weeks or get worse quickly. Avoid alcohol and do not smoke as they can aggravate your conditions.
  • Coping with Diarrhea
    Keep up your intake of fluids and electrolytes (sugars and salts) to avoid getting dehydrated. Eat less fiber (avoid raw fruits, fruit juice and vegetables). Talk to your doctor about possible medication to manage diarrhea. Ask about reducing the dosage of your drug or other suitable treatments.
  • Coping with Infection
    If you have a low level of white blood cells, you are more likely to get infections. There are several ways to reduce your chances of catching or spreading an infection. Avoid unnecessary exposure to germs when you can. Wash your hands frequently and thoroughly with soap or use a sanitiser. Avoid crowds and avoid contact with people who are ill or have infections. Use disposable tissues for coughs and sneezes. Consider using an appropriate face mask. Do not share personal items like cutlery, glasses, towels or toothbrushes with others. Get enough rest and eat a well balanced healthy diet.
  • Coping with Muscle pain
    Tell your doctor straight away because sometimes the muscle pain may be a sign of something more serious. A lower dosage or a different medication might be needed. Try to relax the cramping muscle by stretching it and holding the stretch. You might massage the muscle or apply a heat pad to the area after stretching. Avoid exercising too much. Stay well-hydrated. Do not take over-the-counter pain relievers unless the doctor prescribes it. Your doctor may also suggest taking supplements, such as calcium, magnesium oxide or potassium oxide depending on your needs.
  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Rash
    There are many treatments for a wide range of skin problems. Avoid hot showers or baths because hot water can irritate the skin. Make sure to pat dry your skin after a bath or shower. Do not rub or scratch the affected area. Leave the skin exposed to the air as much as possible. Do not use perfumed soaps or deodorants. Water containing chlorine can make most skin problems worse, so avoid swimming. Avoid spicy foods, alcohol, tobacco smoke and caffeine as it may also make itching worse. Avoid excessive sun exposure. Always use sunscreen and protective clothing when outdoors. Moisturizers can be used regularly to soothe and hydrate the affected area. If it does not get better within a week, speak to a pharmacist or doctor.
  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Weight loss
    As a general rule, speak to your doctor if you lose weight while using this medicine. Losing too much weight can lead to malnutrition. Increase the amount of food you eat. Try eating foods that are high in calories and protein. Drink warm milk instead of tea every so often. Eat smaller meals and eat more often. There may be medicines and physical activities that can improve your condition.Speak to your doctor about this.

How to use Erlonat Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Erlonat 150 Tablet is to be taken empty stomach.

How Erlonat Tablet works

Erlonat 150 Tablet is an anti-cancer medication. Epidermal growth factor receptors (EGFR) are expressed on the lung cancer cell surfaces that modulate their growth. This medicine works by binding the chemical messenger, EGFR, hence, inhibits the cancer signaling pathways mediated by EGFR. This is how it restricts further growth of the cancer cells.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Erlonat 150 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Erlonat 150 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Erlonat 150 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Erlonat 150 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Erlonat 150 Tablet is safe to use in patients with kidney disease. No dose adjustment of Erlonat 150 Tablet is recommended.
Use of this medicine is not advised in patients with severe kidney disease.
Liver
CAUTION
Erlonat 150 Tablet should be used with caution in patients with liver disease. Dose adjustment of Erlonat 150 Tablet may be needed. Please consult your doctor.
Limited information is available on the use of Erlonat 150 Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

What if you forget to take Erlonat Tablet?

If you miss a dose of Erlonat 150 Tablet, skip it and continue with your normal schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
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Quick Tips

  • Erlonat 150 Tablet helps treat non-small cell lung cancer that is locally advanced, or has spread to other areas of the body.
  • It should be taken 1 hour before or 2 hours after the meal.
  • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
  • It makes your skin sensitive towards sunlight. Apply sunscreen or wear protective clothing while going out.
  • It is advisable to avoid smoking while taking this medicine, as it makes the drug ineffective and requires dose adjustment.
  • Do not take it with medication lowering the stomach acid (such as antacids, H2 blockers including ranitidine), as it may affect the working of medicine.
  • Inform your doctor if you develop ulceration in your mouth, changes in your vision or if you experience a worsening cough, shortness of breath, or breathing difficulties while taking this medicine.
  • Your doctor may want you to have regular blood tests to monitor your liver function while you are having treatment with this medicine.
  • Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Patient Concerns

arrow
What is the purpose of Chemotherepy given at the time of radiotherapy in ca lung small cell carcinoma
Dr. Vijay Sharnangat
Medical Oncology and Hematology
This is given to enhance the therapeutic effect of radiation therapy which is curative for small cell lung cancer.
I want to know the symptoms of cancer as I am a smoker
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Symptoms for cancer depends upon which organ involved. For smokers , definitely chronic , they have possibility to develop lung cancer, head and neck cancers, oesophagus cancer, pancreatic cancer, stomach cancer and so more on. General symptoms would be like loss of appetite, weight loss, low grade fever in some cases, chronic cough for long time.
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Do you have any questions related to Erlonat 150 Tablet ?

User Feedback


FAQs

Q. How should Erlonat be taken?

Erlonat is a pill to be taken by mouth, once a day without food as prescribed by your doctor. It is important that you take Erlonat empty stomach, at least 1 hour before or 2 house after meals. It is advisable to take it the same time each day so that you remember when to take it.

Q. Is Erlonat a chemotherapy drug?

Erlonat is not a conventional chemotherapy medicine. Erlonat belongs to a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This in turn helps to slow or stop the spread of cancer cells.

Q. How long can I take Erlonat?

You need to take Erlonat every day, as long as your doctor prescribes it for you. The duration of treatment may vary from person to person.

Q. Does smoking interfere with Erlonat?

Yes, smoking can interfere with the working of Erlonat. It can decrease the effectiveness of the medicine to a great extent. Hence, it is advised to stop smoking before you start Erlonat. Your doctor will need to adjust the dose of Erlonat, if you keep on smoking or there is a change in the pattern of smoking.

Q. What should I do if I get a rash while taking Erlonat?

Rash is a common side effect of Erlonat but you should not stop taking Erlonat because of this. Consult your doctor who will suggest a treatment for it. Also, avoid sun-exposure, use a sunscreen and wear protective clothing.

Q. When can I plan pregnancy, if I am taking Erlonat?

Avoid pregnancy while being treated with Erlonat. If you are a woman of child-bearing age use effective contraception during treatment. Avoid pregnancy for at least 1 month after taking the last tablet.

Q. Does Erlonat affect eyes?

Erlonat commonly causes conjunctivitis and dry eyes. If you develop acute or worsening redness and pain in the eye, increased eye-watering, blurred vision and/or sensitivity to light, immediately inform the doctor as you may need urgent treatment.

Q. When should I call my doctor during treatment with Erlonat?

Inform the doctor if you experience sudden difficulty in breathing associated with cough or fever, severe or ongoing diarrhea, loss of appetite, nausea, and vomiting. Also, consult your doctor if you experience acute or worsening redness and pain in the eye, increased eye-watering, blurred vision and/or sensitivity to light. Let your doctor know in case you are taking a statin (medicine to control cholesterol) along with this medicine and experience unexplained muscle pain, tenderness, weakness, or cramps.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1735-36.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 954-55.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 489-90.
  4. Erlotinib. Seymour, Indiana: Schwarz Pharma Manufacturing; 2014 [revised May 2010]. [Accessed 23 Jan. 2019] (online) Available from:External Link
  5. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Erlotinib. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link
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