Information about Vincristine

How Vincristine works

Vincristine blocks replication of genetic material (DNA) in the cancer cells. Thus it stops the growth and multiplication of cancer cells.

Common side effects of Vincristine

Hair loss, Peripheral neuropathy (tingling and numbness of feet and hand), Constipation
Written By
Reviewed By
MD (Pharmacology), MBBS
Last updated:
24 Mar 2020 | 07:23 AM (UTC)
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Available Medicine for Vincristine

VinlonCelon Laboratories Ltd
481 variant(s)
Biocristin AQBiochem Pharmaceutical Industries
491 variant(s)
CytocristinCipla Ltd
44 to ₹533 variant(s)
UnicristinUnited Biotech Pvt Ltd
551 variant(s)
BiocristinBiochem Pharmaceutical Industries
521 variant(s)
OnvincNeon Laboratories Ltd
491 variant(s)
AlcristAlkem Laboratories Ltd
511 variant(s)
IvinVhb Life Sciences Inc
1051 variant(s)
VcadCadila Pharmaceuticals Ltd
891 variant(s)
VincrystChandra Bhagat Pharma Pvt Ltd
511 variant(s)

Expert advice for Vincristine

  • Vincristine is given as a drip in the vein under the supervision of a doctor.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • Your doctor may get regular blood tests done to monitor your blood cell count, platelet count and liver function.
  • Inform your doctor if you experience skin rash, swelling of face or lips and trouble breathing.

Frequently asked questions for Vincristine


Q. Is Vincristine cardiotoxic/ototoxic?

Vincristine when used in combination with other drugs has shown to be cardiotoxic/ototoxic with unknown cause

Q. Is Vincristine an alkylating agent/ an anthracycline?

Vincristine is vinca alkaloid and not an alkylating agent/ an anthracycline

Q. Is Vincristine a vesicant?

Vincristine is a vesicant (irritant) and can cause damage to the blood vessels if it is not administered properly

Q. Is Vincristine non DNA binding?

Vincristine does not bind to DNA

Q. Is Vincristine neuropathy reversible?

Vincristine neuropathy is not reversible

Q. Is Vincristine FDA approved?

Vincristine is a FDA approved medication

Q. Is Vincristine cytotoxic?

Vincristine is a cytotoxic drug

Q. Does Vincristine cause hair loss/infertility/ lower blood counts/ neutropenia/ neuropathy/ fever/ nausea?

These side effects are commonly observed with the use of Vincristine drug

Q. How does Vincristine affect mitosis?

Vincristine works by interfering with the growth of cancer cells (mitotic inhibition) and slows their spread in the body by causing an arrest of cell division in metaphase

Q. Where does Vincristine come from?

Vincristine is a plant alkaloid comes from the source called Vinca rosea Linn.


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