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Erlotinib

Information

Uses

Erlotinib is used in the treatment of pancreatic cancer, small cell lung cancer, liver cancer, kidney cancer, thyroid cancer, blood cancer (chronic myeloid leukaemia), gastrointestinal stromal tumour, cancer of colon and rectum, non-small cell lung cancer, soft tissue sarcoma (cancer of soft tissue), chronic idiopathic myelofibrosis and breast cancer

How it works

In patients with cancer, a change in DNA (genetic material) triggers a signal which produces abnormal cancer cells. Erlotinib blocks this signal, and thus stops the production of these cancer cells.

Common side effects

Nausea, Fatigue, Breathing difficulty, Rash, Vomiting, Edema, Abdominal pain, Infection, Loss of appetite, Fever, Anemia, Diarrhoea, Weight loss, Bone pain, Stomatitis (Inflammation of the mouth), Constipation

Available Medicine

Showing 10 of 11
  • ₹9514 to ₹11900
    Natco Pharma Ltd
    2 variant(s)
  • ₹5314 to ₹18990
    Dr Reddy's Laboratories Ltd
    2 variant(s)
  • ₹7714 to ₹10395
    Alkem Laboratories Ltd
    2 variant(s)
  • ₹18767 to ₹30570
    Glenmark Pharmaceuticals Ltd
    2 variant(s)
  • ₹40300
    Roche Products India Pvt Ltd
    1 variant(s)
  • ₹11159
    RPG Life Sciences Ltd
    1 variant(s)
  • ₹25500
    Lupin Ltd
    1 variant(s)
  • ₹11000
    Intas Pharmaceuticals Ltd
    1 variant(s)
  • ₹9003
    Reliance Life Sciences
    1 variant(s)
  • ₹9281 to ₹11157
    Zydus Cadila
    2 variant(s)

Expert advice

  • Erlotinib tablets should be taken either 1 hour before or 2 hours after ingestion of food.
  • Erlotinib is not recommended for children and adolescents under 18 years of age.
  • Stop smoking and use effective contraceptive measures while on erlotinib treatment.
  • Do not start erlotinib if you use contact lenses, have had eye problems (ulcers in front part of eye, dry eyes, inflammation in front part of eye), liver or kidney problems, Gilbert’s syndrome (liver disorder that causes increased bilirubin), intolerance to some sugars, are pregnant or breast-feeding.
  • Tell your doctor if you suffer from breathing difficulty associated with fever or cough, severe diarrhea, loss of appetite, nausea or vomiting, severe blistering or peeling of skin, severe pain in abdomen, acute or increasing pain and redness in eye, blurred vision or sensitivity to light, increased eye watering.

Frequently asked questions

Erlotinib

Q.

Is erlotinib cytotoxic, chemotherapeutic drug, biologic or monoclonal antibody?
Erlotinib is not a cytotoxic, chemotherapy drug, or monoclonal antibody. Erlotinib is a biologic tyrosine kinase inhibitor

Q.

Is erlotinib FDA approved?
Yes, erlotinib is approved by FDA

Q.

Does erlotinib cause neutropenia?
Yes, erlotinib can cause neutropenia

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Q.

How long does erlotinib work?
A single dose of erlotinib works for around 36 hours.


Content on this page was last updated on 15 February, 2017, by Dr. Varun Gupta (MD Pharmacology)