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Zedip 25mg Tablet

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Zenith Healthcare Ltd

Composition for Zedip 25mg Tablet

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Primary uses of Zedip 25mg Tablet

Depression, Neuropathic pain, Anxiety disorder
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Medicine Overview of Zedip Tablet

uses

Uses of Zedip Tablet

Zedip 25mg Tablet is used in the treatment of depression, neuropathic pain and anxiety disorder. It is used in patients intolerant of or unresponsive to alternative treatment options for depression.
uses

Zedip Tablet side effects

Common

Dryness in mouth, Blurred vision, Sleepiness, Increased heart rate, Orthostatic hypotension (sudden lowering of blood pressure on standing), Weight gain, Difficulty in urination, Constipation.

uses

How to use Zedip Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zedip 25mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Zedip Tablet works

Zedip 25mg Tablet increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

In Depth Information on Zedip Tablet

Expert advice for Zedip Tablet

  • The main dose should be taken at night as this drug may produce drowsiness or sleepiness.
  • It can take 4 to 6 weeks for Zedip to start working.
  • You should continue the treatment for at least 6 months after you feel better to stop depression from coming back.
  • If your doctor asks you to stop Zedip, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly.
  • Avoid driving or operating machinery as it may decrease alertness.
  • Avoid consuming alcohol when taking the Zedip, as it may cause excessive drowsiness and calmness.
  • The addiction/dependence potential of Zedip is very less.
  • It may be extremely dangerous in overdose.
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Zedip Tablet related warnings
Special precautions for Zedip Tablet
Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Zedip 25mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
CAUTION
Zedip 25mg Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Driving
It is not known whether Zedip 25mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
There is limited information available on the use of Zedip 25mg Tablet in patients with kidney disease. Please consult your doctor.
However, some studies suggest a cautious use of this medicine in patients with kidney disease.
Liver
There is limited information available on the use of Zedip 25mg Tablet in patients with liver disease. Please consult your doctor.

What if you miss a dose of Zedip Tablet?uses

If you miss a dose of Zedip 25mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Patient Concerns

Frequently asked questions about Zedip Tablet

Frequently asked questions about Dosulepin / Dothiepin

No. Zedip is an antidepressant (TCA) that is used to treat depression, nerve pain, and anxiety disorder. It can cause drowsiness or sedation as a side effect. Therefore caution is advised when driving or operating dangerous machinery and even when getting out of bed at night.
No. Zedip is not a muscle relaxant. It is a tricyclic antidepressant (TCA) used in the treatment of depression, nerve pain, and anxiety disorder.
Q. What is the difference between Zedip and amitriptyline?
Zedip is chemically related to Amitriptyline and both are tricyclic antidepressant (TCA) medicine. There is overlap in pharmacological property of this medicine.
Q. Is Zedip the same as doxepin?
Zedip and doxepin are different medicines but belong to the similar chemical class. Doxepin, at low doses, can improve sleep in patients with insomnia. It is also available in the topical form for use in various neuro-dermatitis syndrome, especially itching.
If your doctor asks you to stop Zedip, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly. Sudden discontinuation may cause aggression, anxiety, blurred vision, concentration impairment, constipation and crying spell.
Yes. Zedip can be fatal (can cause death) in overdose. This is due to a life-threatening or dangerous side effect in overdose like hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death. That's why it is generally not considered a first-line option for depression because of side effect profile.
Q. Can Zedip be used along with mirtazapine?
It is better to avoid Zedip with mirtazapine. Mirtazapine, which is used in the treatment of depression, can potentiate the sedative effects of Zedip.
Q. Can Zedip be used with citalopram?
No. Citalopram and Zedip both are the antidepressant. Citalopram may increase the high blood level of Zedip. This may lead to a life-threatening or dangerous side effect of hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death.
Q. Can Zedip be used with sertraline?
No. Sertraline and Zedip both are the anti-depressant. Sertraline may increase the high blood level of Zedip. This may lead to a life-threatening or dangerous side effect of hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death.
Q. Can I take Zedip with diazepam?
It is better to avoid this combination. Diazepam is a sedative drug and Zedip may cause sedation as a side effect too. Taking both of them together can increase the drowsiness or sleepiness. Inform your doctor if you are taking diazepam.
No. Zedip is not approved for the treatment of trigeminal neuralgia. Trigeminal neuralgia is a chronic pain condition that affects the trigeminal or 5th cranial nerve, one of the most widely distributed nerves in the head.
No. Zedip is not approved for the treatment of burning mouth syndrome. Burning mouth syndrome is a painful condition of mouth that is burning, scalding, tingling or feeling of numbness that may occur every day for months or longer.
Yes. Zedip is indicated for the treatment of depression. It has a potential advantage in the patient with depression if associated with insomnia and anxiety. It is generally not considered a first-line option for depression because of side effect profile but very useful for severe or treatment-resistant depression.
No. Zedip is not approved for the treatment of Irritable Bowel Syndrome (IBS). Irritable Bowel Syndrome is a functional gastrointestinal disorder characterised by chronic or recurrent abdominal pain or discomfort associated with altered bowel habits.
Yes. Zedip may be used for the treatment of insomnia (too much arousal both at night and during the day) associated with depression. Because it can cause drowsiness or sedation as side effects, it is effective in treating insomnia associated with depression.
Yes. Zedip is not approved for the treatment of fibromyalgia. Fibromyalgia is a pain syndrome with tenderness but no structural pathology in muscles, ligamanets or joints.
Yes. Zedip is indicated for the treatment of nerve pain/neuropathic pain. Chronic pain/Neuropathic pain is described as pain that arises from damage to, or dysfunction of, any part of peripheral or central nervous system. It is associated with the disease which can affect nerves like diabetes mellitus or herpes infections.

Severely interacts with other drugs like

Taking Zedip with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Zedip with Moclobemide
LIFE-THREATENING
Medicines with composition Moclobemide: Trima, Rimarex
Zedip with Moxonidine
LIFE-THREATENING
Medicines with composition Moxonidine: Moxilong, Moxcent, Moxovas, Moxopress
Zedip with Terbinafine
SERIOUS
Medicines with composition Terbinafine: Terbicutis, Tzorg, Terbicide, Tinazen, Zygter, Terfast, Fluty TF, Terbit, Tinafine
Zedip with Etizolam
SERIOUS
Medicines with composition Etizolam: Etilax, Etirest, Etimark, Etizep, Etilaam, Solopose, Lam ET, Suprabenz, Sylkam, Etizoram, New Zomnia
Zedip with Codeine
SERIOUS
Medicines with composition Codeine: Montokuf
Zedip with Citalopram
SERIOUS
Medicines with composition Citalopram: Vocita, Olarc, Citopam, Cetadep, Cita, Topdep, Celica, Citalomine, Citalent, Citola, Cytop, Madam
Zedip with Chlordiazepoxide
SERIOUS
Medicines with composition Chlordiazepoxide: Zepox, Anxibrium, Poxid, Peaceoxide, Anxon H, Equilibrium, Cloxide, Librel, Anxizide, Librate
Zedip with Butorphanol
SERIOUS
Medicines with composition Butorphanol: Butodol
Zedip with Indinavir
SERIOUS
Medicines with composition Indinavir: Indivan
Zedip with Lithium
SERIOUS
Medicines with composition Lithium: Lithocent, Lisalt, Lithocap, Carbolith, Hethium, Zecarb, Lalithium, T Lith, Tricab
Zedip with Ritonavir
SERIOUS
Medicines with composition Ritonavir: Viriton, Ritomune, Ritomax
Zedip with Clobazam
SERIOUS
Zedip with Primidone
SERIOUS
Medicines with composition Primidone: Mysoline
Zedip with Rasagiline
SERIOUS
Medicines with composition Rasagiline: Rasalect, Relgin
Zedip with Midazolam
SERIOUS
Medicines with composition Midazolam: Medzol, Mezolam, Midfast, Fulsed, Midosed, Midzee, Benzosed, Megarest
Zedip with Paroxetine
SERIOUS
Medicines with composition Paroxetine: Parox, Pirotin, Paropex, Depaxil, Patriot, Xet, Parocen, Paroxee, Pxt, Praxet, Parot, Paxidep, Pxn, Emoxet, Paxiford, XL Paro
Zedip with Clonidine
SERIOUS
Medicines with composition Clonidine: Arkamin, Cloneon, Catapres
Zedip with Diazepam
SERIOUS
Medicines with composition Diazepam: Peptica, Placidox, Shipam, Anxol, D P M, Paxum, Dizep, Starlium, Repam, Clampose
Zedip with Nitrazepam
SERIOUS
Medicines with composition Nitrazepam: Nap, Nitraz, Nzm, Sopor, N Tra, Nira, Hypnoril, Nitab, Hypnocent, Nite, Nitrosun, Nitavan
Zedip with Nalbuphine
SERIOUS
Medicines with composition Nalbuphine: Rubuphine, Nalfy, Nacphin
Zedip with Fluvoxamine
SERIOUS
Medicines with composition Fluvoxamine: Voxinix, Uvox, Voxidep, Voxazen, Voxamin, Psyvoxin, Fluxam, Sorest, Fluvoxin, Fluvo
Zedip with Pentazocine
SERIOUS
Medicines with composition Pentazocine: Fortwin
Zedip with Ethylmorphine
SERIOUS
Medicines with composition Ethylmorphine: Dionindon
Zedip with Venlafaxine
SERIOUS
Medicines with composition Venlafaxine: Venlift, Ventee, Venpad, Venlor, Venla, Flavix, Venjoy, Nutraport, Venlaway, Sentosa, Ventin, Veniz
Zedip with Phenobarbitone
SERIOUS
Medicines with composition Phenobarbitone: Nytoin, Barbee, Gardenal, Fenobarb, Luminal, Beetal, Emgard
Zedip with Dapoxetine
SERIOUS
Medicines with composition Dapoxetine: Actinex, DA Sutra, Stay Tal, Dapoxy, Dapnex, Duraject, Appynite, Ristor, Dejac
Zedip with Lorazepam
SERIOUS
Zedip with Cinacalcet
SERIOUS
Medicines with composition Cinacalcet: Capicet, Setz

Substitutes for Zedip Tablet

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