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Wyclovir 250mg Injection

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 31 Mar 2026 | 02:31 PM (IST)
Wyclovir 250mg Injection is an antiviral medicine. It helps in treating viral infections like herpes labialis, herpes simplex virus infections, shingles, genital herpes infection, and chickenpox. It prevents the multiplication of viruses in human cells and therefore helps in clearing the infection.
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General Information

Contains

Acyclovir (250mg)

Marketer

Salvus Pharma

Storage

Store below 30°C
The content is shown in English
Wyclovir 250mg Injection image
Wyclovir 250mg Injection image

Product introduction

Wyclovir 250mg Injection is administered as an injection by a healthcare professional. Kindly do not self-administer. It is given by slow intravenous (I.V.) infusion over a 1-hour period to avoid damage to kidneys. You should drink plenty of water while on treatment with this medicine as it helps to prevent dehydration and kidney damage.

Some side effects include vomiting, nausea, and increased liver enzymes. You may also notice some injection site reactions like pain, swelling, or redness. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Uses of Wyclovir Injection

Benefits of Wyclovir Injection

Herpes labialis
Herpes labialis causes recurrent cold sores around the lips and mouth. Wyclovir 250mg Injection helps shorten the healing time of sores, reduce pain and irritation, and lower the frequency of future outbreaks.
Genital herpes infection
Genital herpes leads to painful sores, itching, and discomfort in the genital area. Wyclovir 250mg Injection helps reduce symptom severity, promotes faster healing of lesions, and supports better long-term control of recurrent episodes.
Chickenpox
Chickenpox causes itchy blisters, fever, and general discomfort, especially in older children and adults. Wyclovir 250mg Injection helps reduce the intensity of symptoms and supports faster healing of skin lesions, improving overall comfort.
Herpes Simplex Virus Infections
Herpes simplex virus infections cause painful blisters and sores on the skin or mucous membranes. Wyclovir 250mg Injection helps reduce the severity and duration of symptoms, supports faster healing of sores, and lowers the chance of frequent flare-ups.
Shingles
Shingles is caused by reactivation of the chickenpox virus and leads to painful rashes and nerve pain. Wyclovir 250mg Injection helps limit viral activity, which can reduce rash severity, ease pain, and support quicker recovery when started early.

Side effects of Wyclovir Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Wyclovir
  • Vomiting
  • Rash
  • Nausea
  • Dry skin
  • Burning sensation
  • General discomfort
  • Itching
  • Urticaria
  • Inflammation of vein
  • Dry lips
  • Skin peeling

How to use Wyclovir Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Wyclovir Injection works

Wyclovir 250mg Injection is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

All substitutes for Wyclovir 250mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Axovir 250mg Injection

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₹254.9/injection
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Vir 250mg Injection

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₹441.75/injection
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Neoclovir 250mg Injection

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₹362.8/injection
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Acycloveer G 250mg Injection

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Alsacir 250mg Injection

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Quick tips

  • It is given by slow intravenous (I.V.) infusion over a 1-hour period to avoid damage to kidneys.
  • Drink plenty of water while on treatment with this medicine. This helps to prevent dehydration and kidney damage.
  • If you have genital herpes, use barrier methods (condoms) for contraception and avoid sexual contact while the sores are present.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • Drink plenty of water while on treatment with this medicine. This helps to prevent dehydration and kidney damage.
  • If you have genital herpes, use barrier methods (condoms) for contraception and avoid sexual contact while the sores are present.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Wyclovir 250mg Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Wyclovir 250mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Wyclovir 250mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

NOT RELEVANT
Not relevant, as Wyclovir 250mg Injection is intended for use in hospitalized patients.
Kidney

Kidney

CAUTION
Wyclovir 250mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
It is advisable to drink plenty of water while you are taking this medicine.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Wyclovir 250mg Injection in patients with liver disease.

Interaction with drugs

Taking Wyclovir with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Tenofovir disoproxil fumarate (Oral Route)

Do not consume Tenofovir disoproxil fumarate with Acyclovir. If concurrent use is essential, your doctor may monitor your kidney function closely.
Severe

Tacrolimus (Oral Route)

If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.
Severe

Ciclosporin (Oral Route)

Caution is advised when taking Ciclosporin with Acyclovir. Your doctor may closely monitor the effects of Acyclovir if used concurrently with Ciclosporin and adjust the dose if needed. Acyclovir may raise blood levels of Ciclosporin.
Severe

Ciclosporin (Injection Route)

Caution is advised when taking Ciclosporin with Acyclovir. Your doctor may closely monitor the effects of Acyclovir if used concurrently with Ciclosporin and adjust the dose if needed. Acyclovir may raise blood levels of Ciclosporin.
Moderate

Tizanidine (Oral Route)

Do not consume Tizanidine with Acyclovir. If concurrent use is essential, watch out for symptoms such as breathlessness, fatigue, drowsiness, sedation or faintness or vomiting and consult your doctor if you experience them. They may monitor and adjust the doses as per the observations. Acyclovir may raise blood levels of Tizanidine.

Frequently asked questions

Wyclovir 250mg Injection is an antiviral medicine effective against herpes simplex and varicella zoster viruses. It does not cure infections caused by these viruses but helps to minimize the symptoms and shorten the duration of infection. It does not remove the viruses from the body but prevents the viruses from dividing and spreading.
Wyclovir 250mg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. It is given by slow intravenous (I.V) infusion over a one hour period to avoid damage to kidneys. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Wyclovir 250mg Injection.
No, you can infect other people, even while you are being treated with Wyclovir 250mg Injection. Herpes infections are contagious, so avoid letting infected areas come into contact with other people. Avoid touching your eyes after touching an infected area. Wash your hands frequently to prevent transmitting the infection to others. You should practice safe sex by using condoms. You should not have sex if you have genital sores or blisters.
Serious side effects are rare, but if you experience them, you should seek medical advice right away. These rare side effects include hives, blistering or peeling rash, yellow skin or eyes, unusual bruising or bleeding, loss of consciousness, fits, difficulty in breathing, hallucinations and swelling of the face, tongue, lips or throat.
Older adults (over age 65 years) tend to experience more side effects when taking Wyclovir 250mg Injection. The reason being, their kidneys do not flush the drug out of their system as quickly as a younger person’s kidneys would do. Elderly patients should drink plenty of water while taking Wyclovir 250mg Injection, and their kidney function should be monitored. These patients should be given a lower dose and should be monitored for neurological problems.
Accidental, repeated overdoses of oral Wyclovir 250mg Injection over several days have resulted in nausea, vomiting, confusion and headache. Consult your doctor in case of overdose.
Patients with advanced HIV disease or patients with an impaired immunity have reported resistance to Wyclovir 250mg Injection. If you are not responding to Wyclovir 250mg Injection, the possibility of drug resistance should be checked.
Hair loss is an uncommon side effect of Wyclovir 250mg Injection. It stops when the medicine is discontinued.
Wyclovir 250mg Injection is an antiviral medicine effective against herpes simplex and varicella zoster viruses. It does not cure infections caused by these viruses but helps to minimize the symptoms and shorten the duration of infection. It does not remove the viruses from the body but prevents the viruses from dividing and spreading.
No, you can infect other people, even while you are being treated with Wyclovir 250mg Injection. Herpes infections are contagious, so avoid letting infected areas come into contact with other people. Avoid touching your eyes after touching an infected area. Wash your hands frequently to prevent transmitting the infection to others. You should practice safe sex by using condoms. You should not have sex if you have genital sores or blisters.
Serious side effects are rare, but if you experience them, you should seek medical advice right away. These rare side effects include hives, blistering or peeling rash, yellow skin or eyes, unusual bruising or bleeding, loss of consciousness, fits, difficulty in breathing, hallucinations and swelling of the face, tongue, lips or throat.
Older adults (over age 65 years) tend to experience more side effects when taking Wyclovir 250mg Injection. The reason being, their kidneys do not flush the drug out of their system as quickly as a younger person’s kidneys would do. Elderly patients should drink plenty of water while taking Wyclovir 250mg Injection, and their kidney function should be monitored. These patients should be given a lower dose and should be monitored for neurological problems.
Accidental, repeated overdoses of oral Wyclovir 250mg Injection over several days have resulted in nausea, vomiting, confusion and headache. Consult your doctor in case of overdose.
Patients with advanced HIV disease or patients with an impaired immunity have reported resistance to Wyclovir 250mg Injection. If you are not responding to Wyclovir 250mg Injection, the possibility of drug resistance should be checked.
Hair loss is an uncommon side effect of Wyclovir 250mg Injection. It stops when the medicine is discontinued.

Fact Box

Chemical Class

Hypoxanthines

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Antiviral Agents (Non-HIV)

Related lab tests

Herpes Simplex Virus 1 DNA PCR

Herpes Simplex Virus 1 IgG

Herpes Simplex Virus 2 DNA PCR

Herpes Simplex Virus 2 IgG

Herpes Simplex Virus 2 IgM

Varicella Zoster IgG

Varicella Zoster IgM

References

  1. Acosta EP, Flexner C. Antiviral Agents (Nonretroviral). In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1594-1600.
  2. Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 846-47.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 18-22.
  4. Aciclovir. Hayes, UK: Ranbaxy (UK) Limited a Sun Pharmaceutical Company; 2007 [revised 15 Aug. 2018]. [Accessed 29 Jan. 2019] (online) Available from:
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 29 Mar. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Salvus Pharma
Address: SCF-390, Ground Floor, M – Market, Manimajra, Chandigarh – 160101, India

Vendor Details

Country of origin: India

Lab tests offered by us

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