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Ceftriaxone is used in the treatment of bacterial infections and typhoid fever

How it works

Ceftriaxone is an antibiotic. It kills the bacteria by attacking their cell wall. Specifically, it prevents the synthesis of a substance in the cell wall called peptidoglycan, which provides the cell wall with the strength required for survival of bacteria in human body.

Common side effects

Nausea, Headache, Itching, Allergic reaction, Fever, Vomiting, Diarrhoea

Available Medicine

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Expert advice

  • It is given as a drip (intravenous infusion) or as an injection directly into a vein or into a muscle. It is made up by the doctor, or nurse using water for injections or a suitable infusion fluid.
  • Do not drive because you may feel sleepy or dizzy while being treated with ceftriaxone.
  • Tell your doctor if you are taking, have recently taken or might take any other medicines. This includes medicines you can obtain without a prescription. 
  • Do not start or continue the ceftriaxone and consult your doctor if you have a liver or   kidney disease.
  • Do not take this drug and consult your doctor  if you are pregnant or planning to become pregnant or breastfeeding.

Frequently asked questions



Is ceftriaxone a form of penicillin drug?
No, ceftriaxone is not a penicillin drug


Is it bactericidal or bacteristatic?
It is a cephalosporin antibiotic. It is bactericidal drug


Is ceftriaxone safe in liver disease?
Yes, ceftriaxone is safe in liver disease. Please consult your doctor for your medical condition before taking the drug

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Is ceftriaxone compatible with potassium or potassium chloride?
Yes, ceftriaxone is compatible with potassium or potassium chloride when taken together


Is ceftriaxone the same as cephalexin, Monocef-o, Monocef 200, Monocef tablet, Cefakind, or Cefakind 250?
No, all are different cephalosporin antibiotics. Monocef-o, Monocef 200, or Monocef tablet contain cefpodoxmine, and Cefakind, or Cefakind 250 contain cefuroxime


What organisms does ceftriaxone cover?
Ceftriaxone is active against pseudomonas, staphylococcus, and klebsiella bacteria. It has no activity against chlamydia, methicillin-resistant Staphylococcus aureus (mrsa), and mycoplasma.

Content on this page was last updated on 14 February, 2017, by Dr. Varun Gupta (MD Pharmacology)