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Tacrolimus is used in organ transplantation

How it works

Tacrolimus suppresses the activity of body's immune system and prevents rejection of the transplanted organ.

Common side effects

Headache, Nausea, Insomnia (difficulty in sleeping), Diarrhoea, Renal dysfunction, Increased glucose level in blood, Tremor

Available Medicine

Showing 10 of 39
  • ₹127 to ₹746
    Panacea Biotec Ltd
    5 variant(s)
  • ₹126 to ₹1724
    6 variant(s)
  • ₹175 to ₹1878
    Emcure Pharmaceuticals Ltd
    4 variant(s)
  • ₹130 to ₹367
    Glaxo SmithKline Pharmaceuticals Ltd
    2 variant(s)
  • ₹140 to ₹459
    Torrent Pharmaceuticals Ltd
    4 variant(s)
  • ₹388 to ₹924
    Alembic Pharmaceuticals Ltd
    2 variant(s)
  • ₹99 to ₹439
    Alkem Laboratories Ltd
    3 variant(s)
  • ₹190 to ₹262
    Ajanta Pharma Ltd
    3 variant(s)
  • ₹175 to ₹1700
    Zydus Cadila
    3 variant(s)
  • ₹161 to ₹438
    Mohrish Pharmaceuticals
    5 variant(s)

Expert advice

  • Take tacrolimus on empty stomach or 2-3 hours after a meal.
  • Do not take tacrolimus if you are allergic to it or to any other content in the medicine; or to sirolimus or other macrolide antibiotics (erythromycin, clarithromycin).
  • Doctor’s advice should be considered in case of patients with following history of disease conditions: liver problems, abnormal electrical signaling of the heart (QT interval prolongation), or diarrhea lasting for more than a day; abdominal pain, with or without vomiting, nausea, chills and fever.
  • Avoid using tacrolimus if you are pregnant or planning to become pregnant or breast-feeding a baby.
  • Limit exposure to the sun while taking the drug. Wear protective clothing and use sunscreen when stepping out in the sun, to prevent skin cancer.
  • Do not drive or operate heavy machinery while taking tacrolimus as it may cause dizziness.

Frequently asked questions



Is tacrolimus a steroid?
Tacrolimus is an immunosuppressant drug. It is not a steroid drug


Is tacrolimus nephrotoxic or cytotoxic?
Tacrolimus may cause destruction of certain types of cells (cytotoxic) and may impair kidney function (nephrotoxic). Patients should follow the advice of the doctor regarding its use


Is tacrolimus the same as Prograf?
Yes. Progarf is a branded form of tacrolimus available in the market

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Is tacrolimus safe?
Yes. Tacrolimus is relatively safe if used as recommended. In case of any side-effects, consult your doctor


Can I take tacrolimus with omeprazole?
Omeprazole may increase the blood levels of tacrolimus. It can be taken with omeprazole only if prescribed by your doctor


Does tacrolimus cause diabetes, hair loss, tiredness, or depression?
Tacrolimus may cause diabetes, hair loss, tiredness, or depression. If you experience any such symptoms, please consult your doctor.

Content on this page was last updated on 21 March, 2017, by Dr. Varun Gupta (MD Pharmacology)