Trunate 60 Tablet

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 25 Nov 2025 | 03:05 PM (IST)

Trunate 60 Tablet is used to lower blood sugar levels in adults with type 2 diabetes mellitus. It is usually prescribed along with other diabetes medicines to achieve adequate blood sugar control. It also prevents serious complications of diabetes like kidney damage and blindness.

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General Information

Contains

Nateglinide (60mg)

Marketer

AAR ESS Remedies Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Trunate 60 Tablet is normally prescribed when diet and exercise alone or other medicines have not been enough to control your blood sugar level. It works best when taken before meals. The dose will depend on your condition, and blood sugar levels, but you should use it as advised by your doctor.

You should take it regularly, at the same time each day, to get the most benefit and you should not stop unless your doctor recommends it. It is controlling your blood sugar levels and helping to prevent serious complications in the future. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.

The most common side effects of this medicine include upper respiratory tract infection, back pain, diarrhea, flu symptoms, dizziness, and joint pain. Contact your doctor if the side effects worry you or if they do not go away.

Before taking this medicine, let your doctor know if you have ever had kidney disease, heart or pancreas problems, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines you are taking may interfere with it so make sure your doctor knows about all the other medicines you are using. Limit your alcohol intake while taking this medicine because it can increase your risk of developing low blood sugar levels. You may need regular tests such as kidney function and blood glucose levels to check that the medicine is working properly.

Uses of Trunate Tablet

Type 2 diabetes mellitus

Benefits of Trunate Tablet

Type 2 diabetes mellitus
Type 2 diabetes mellitus is a long-term condition where the body cannot effectively use insulin, leading to high blood sugar levels. Trunate 60 Tablet helps lower blood sugar, especially after meals, and supports better overall glucose control. It helps reduce the risk of diabetes-related complications like fatigue, blurred vision, and long-term damage to the heart, kidneys, and nerves, making it easier for individuals to maintain a healthier and more active life.

Side effects of Trunate Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Trunate

Upper respiratory tract infection
Back pain
Diarrhea
Flu-like symptoms
Dizziness
Joint pain

How to use Trunate Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trunate 60 Tablet is to be taken on an empty stomach.

How Trunate Tablet works

Trunate 60 Tablet is an anti-diabetic medication. It increases the amount of insulin released by the pancreas which prevents blood glucose from rising very high after meals.

All substitutes for Trunate 60 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Nateglide 60mg Tablet

by Druto Laboratories

₹19.4/tablet

3% cheaper

Quick tips

It may cause dizziness. Do not drive or do anything that requires mental focus until you know how Trunate 60 Tablet affects you.
It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
Monitor your blood sugar levels regularly while you are taking this medicine.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Trunate 60 Tablet results in fast and effective control of high blood sugar following meals.
For best results, take Trunate 60 Tablet 15 to 30 minutes before a meal.
If you miss a meal, skip your dose to avoid hypoglycemia (low blood sugar level).
You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Trunate 60 Tablet
It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
Monitor your blood sugar levels regularly while you are taking this medicine.
It may cause dizziness. Do not drive or do anything that requires mental focus until you know how Trunate 60 Tablet affects you.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Trunate 60 Tablet

Pregnancy

CONSULT YOUR DOCTOR

The safety of Trunate 60 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

SAFE IF PRESCRIBED

Trunate 60 Tablet may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Monitor the breastfed baby’s blood sugar during treatment with Trunate 60 Tablet

Driving

CAUTION

Trunate 60 Tablet may affect your driving ability if your blood sugar becomes too low or too high. Monitor your blood glucose and avoid driving if affected.

Kidney

SAFE IF PRESCRIBED

Trunate 60 Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.

Liver

CAUTION

Trunate 60 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Limited data are available on the use of Trunate 60 Tablet in patients with moderate to severe liver disease.

Interaction with drugs

Taking Trunate with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Disopyramide (Oral Route)

If concurrent use is essential, watch out for symptoms such as confusion, headache, nausea, dizziness or faintness and consult your doctor if you experience them.

Moderate

Asparaginase (Injection Route)

Your doctor may monitor your diabetic control closely and adjust the doses as per the observations.

Moderate

Fenfluramine (Oral Route)

Your doctor may monitor your diabetic control closely and adjust the doses as per the observations.

Moderate

Bortezomib (Injection Route)

Your doctor may monitor blood glucose levels and adjust the dose, if required.

Moderate

Leflunomide (Oral Route)

Watch out for symptoms of Nateglinide side effects such as back pain, dizziness, cough, diarrhea, congestion, headache or nausea and consult your doctor if you experience them. They may adjust the doses as per the observations. Leflunomide may raise blood levels of Nateglinide.

Frequently asked questions

Does Trunate 60 Tablet cause weight gain?

Weight gain may occur with Trunate 60 Tablet therapy. If this effect persists or worsens, notify your doctor or pharmacist promptly

Does Nateglinide contain metformin?

Nateglinide does not contain metformin

How does Trunate 60 Tablet work?

Trunate 60 Tablet belongs to a class of drugs called meglitinides. Trunate 60 Tablet helps your body to regulate the amount of glucose in your blood by stimulating the pancreas to release insulin.

Fact Box

Chemical Class

Phenylalanine derivative

Habit Forming

Therapeutic Class

ANTI DIABETIC

Action Class

Meglitinides (Insulin Secretagogues)

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1257-58.
Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 741.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 961-62.
Nateglinide. Spring Valley, New York: Par Pharmaceutical Companies, Inc.; 2009. [Accecssed 13 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Nateglinide. [Updated 2019 Feb 7]. [Accessed 18 Feb. 2020] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: AAR ESS Remedies Pvt Ltd
Address: Aar Ess Remedies Private Limited, C-28, Sector-65, Noida-201301, Uttar Pradesh, India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Trunate 60 Tablet

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Trunate Tablet

Benefits of Trunate Tablet

Side effects of Trunate Tablet

How to use Trunate Tablet

How Trunate Tablet works

All substitutes for Trunate 60 Tablet

Nateglide 60mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Disopyramide (Oral Route)

Asparaginase (Injection Route)

Fenfluramine (Oral Route)

Bortezomib (Injection Route)

Leflunomide (Oral Route)

Frequently asked questions

Does Trunate 60 Tablet cause weight gain?

Does Nateglinide contain metformin?

How does Trunate 60 Tablet work?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests