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Nateglinide

Written By Dr. Subita AlaghReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:34 AM (UTC)

Nateglinide Uses

Nateglinide is used in the treatment of type 2 diabetes mellitus.

How Nateglinide works

Nateglinide is an anti-diabetic medication. It increases the amount of insulin released by the pancreas which prevents blood glucose from rising very high after meals.

Common side effects of Nateglinide

Dizziness, Back pain, Diarrhea, Flu-like symptoms, Upper respiratory tract infection, Arthropathy
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Expert advice for Nateglinide

  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how  Nateglinide affects you.
  • It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
  • Monitor your blood sugar levels regularly while you are taking this medicine.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. 
  • Nateglinide results in fast and effective control of high blood sugar following meals.
  • For best results, take Nateglinide 15 to 30 minutes before a meal.
  • If you miss a meal, skip your dose to avoid hypoglycemia (low blood sugar level).
  • You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Nateglinide
  • It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
  • Monitor your blood sugar levels regularly while you are taking this medicine.
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how  Nateglinide affects you.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. 

Frequently asked questions for Nateglinide

Weight gain may occur with Nateglinide therapy. If this effect persists or worsens, notify your doctor or pharmacist promptly
Nateglinide does not contain metformin
Nateglinide belongs to a class of drugs called meglitinides. Nateglinide helps your body to regulate the amount of glucose in your blood by stimulating the pancreas to release insulin.