Bortezomib is used in the treatment of multiple myeloma and mantle-cell lymphoma.
How it works
Bortezomib belongs to the class of drugs called proteasome inhibitors. Proteasomes are proteins which play an important role in growth and multiplication of cancer cells. Bortezomib blocks the action of proteasome, and reduces the growth of cancerous (actively growing) cells.
Common side effects
Reduced blood platelets, Psychiatric disturbances, Vomiting, Nausea, Loss of appetite, Fever, Anemia, Diarrhoea, Peripheral neuropathy (tingling and numbness of feet and hand), Decreased appetite, Low energy, Decreased white blood cell count (neutrophils), Constipation
- ₹12500 to ₹12688Natco Pharma Ltd2 variant(s)
- ₹13125 to ₹18522Dr Reddy's Laboratories Ltd2 variant(s)
- ₹15852Emcure Pharmaceuticals Ltd1 variant(s)
- ₹15864Intas Pharmaceuticals Ltd1 variant(s)
- ₹15201Cadila Pharmaceuticals Ltd1 variant(s)
- ₹11904Panacea Biotec Ltd1 variant(s)
- ₹15507Pfizer Ltd1 variant(s)
- ₹12696Zuventus Healthcare Ltd1 variant(s)
- ₹3999 to ₹12020Glenmark Pharmaceuticals Ltd2 variant(s)
- ₹11308RPG Life Sciences Ltd1 variant(s)
- Before taking bortezomib, consult your doctor if you have any of the following disease conditions: disease of liver, kidney, heart or infections like fever with rash or genital sores, diabetes, low number of red or white blood cells or bleeding problems.
- Drink plenty of fluids every day during your treatment with bortezomib.
- Tell your doctor if you are or planning to become pregnant or are breastfeeding.
- Consult your doctor if you have signs of serious brain infection such as memory loss, trouble in thinking, difficulty with walking or loss of vision.
- Do not drive or operate machinery after taking bortezomib as it may cause tiredness, dizziness, fainting or blurred vision.
Frequently asked questions
Q. Is bortezomib a chemotherapy/hormonal drug/ cytotoxic?
Bortezomib is not a hormone. It is a chemotherapy/ cytotoxic drug used in the treatment of cancers including multiple myeloma and mantle cell lymphoma
Q. How does bortezomib work?
Bortezomib belongs to the class of drugs called a proteasome inhibitor. It acts by blocking the action of proteasome, and affects the growth of cancerous (actively growing) cells
Q. Is bortezomib FDA approved?
Yes, bortezomib is approved by FDA
Q. Is bortezomib dialyzable?
Yes, bortezomib is dialyzable
Q. Is bortezomib toxic?
Bortezomib can cause toxic effects if not given in appropriate dose although not everybody gets them
Q. Does bortezomib cause constipation?
Bortezomib may cause side effects such as constipation.