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Trazonil 25 Tablet

Trazodone (25mg)

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Trazonil 25 Tablet is used in the treatment of depression. This medicine helps by increasing the level of chemical messengers in the brain that relax the nerves and have a calming effect on the brain.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 07 Apr 2026 | 02:54 PM (IST)

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General Information

Contains

Trazodone (25mg)

Marketer

Intas Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Trazonil 25 Tablet should be taken with food. It is advised to take this medicine at a fixed time each day. You should never skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly as it may worsen your symptoms.

Some common side effects of this medicine include constipation and blurred vision. It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus. Moreover, most of the side effects are immediate and often go away with time. Please consult your doctor if these bother you or do not go away.

Before taking Trazonil 25 Tablet, it is important to inform your doctor if you have any history of fits, severe kidney, liver, or heart problems, narrow-angle glaucoma, or any mental disorder. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression if you have any suicidal thoughts.

Uses of Trazonil Tablet

Depression

Benefits of Trazonil Tablet

Depression
Trazonil 25 Tablet is used in the treatment of depression, a mental health condition marked by persistent sadness, lack of interest, and low energy. This medicine helps improve mood, emotional stability, and sleep patterns, thereby enhancing overall quality of life in individuals struggling with depression.

Side effects of Trazonil Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Trazonil

Vomiting
Dizziness
Confusion
Blurred vision
Headache
Fatigue
Nausea
Sleepiness
Dryness in mouth
Constipation
Edema (swelling)
Hypotension (low blood pressure)
Fainting
Drowsiness
Nasal congestion (stuffy nose)
Weight gain
Weight loss
Pain

How to use Trazonil Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trazonil 25 Tablet should be taken with or after food.

How Trazonil Tablet works

Trazonil 25 Tablet modulates the level of serotonin in the brain. Serotonin is a chemical messenger in the brain that helps in regulating the mood.

All substitutes for Trazonil 25 Tablet

For information purposes only. Consult a doctor before taking any medicine.

TripAX 25 Tablet

by Alteus Biogenics Pvt Ltd

₹4.16/tablet

1% cheaper

Quick tips

It makes you feel sleepy. Take it in the evening or before you go to bed.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Do not drive or do anything that requires mental focus until you know how Trazonil 25 Tablet affects you.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Trazonil 25 Tablet may cause excessive drowsiness when taken with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Trazonil 25 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CAUTION

Trazonil 25 Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

UNSAFE

Trazonil 25 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Trazonil 25 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
However, talk to your doctor if you have any underlying kidney disease as this medicine should be used cautiously.

Liver

CAUTION

Trazonil 25 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine.

Interaction with drugs

Taking Trazonil with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Moclobemide (Oral Route)

Do not consume Moclobemide with Trazodone. If Moclobemide is essential, ensure a gap of at least 1 day after discontinuing Trazodone. Please consult your doctor.

Life-threatening

Domperidone (Oral Route)

Do not consume Domperidone with Trazodone.

Life-threatening

Tranylcypromine (Oral Route)

Do not consume Tranylcypromine with Trazodone. If Tranylcypromine is essential, ensure a gap of at least 2 weeks after discontinuing Trazodone. Please consult your doctor.

Severe

Thioridazine (Oral Route)

Do not consume Thioridazine with Trazodone. If concurrent use is essential, watch out for symptoms such as sleepiness, dry mouth, impaired voluntary movements, weight gain, constipation, muscle stiffness or tremors and consult your doctor if you experience them. They may adjust the dose of Thioridazine accordingly. Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Severe

Amiodarone (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Frequently asked questions

Is trazodone a mono amine oxidase inhibitor/ selective serotonin reuptake inhibitor/ opiate/ barbiturate/ anti cholinergic/ habit forming/ controlled substance?

Trazodone is not a mono amine oxidase inhibitor/ selective serotonin reuptake inhibitor/ opiate/ barbiturate/ anti cholinergic/ habit forming/ controlled substance

Is trazodone taken for anxiety?

Trazodone is taken for anxiety and depression

Is trazodone taken for sleep or pain?

Trazodone is not prescribed for sleep or pain relief

Does trazodone have sulpha?

Trazodone does not have sulpha in it

Does trazodone cause fluctuation in blood pressure/ diarrhea/ feeling high?

Trazodone may cause blood pressure fluctuations. It is not known to cause diarrhea/ feeling high

Does trazodone cause anxiety or depression?

It is given for the treatment of anxiety and depression. Please consult your doctor for any observed side effects

Can trazodone be taken with nyquil/ benadryl/ zoloft/ Cymbalta/ valium/ paxil/ flexeril/ melatonin/ xanax?

Trazodone cannot be taken with Nyquil/ Benadryl/ Zoloft/ Cymbalta/ valium/ paxil/ flexeril/ Xanax. Trazodone can be taken with melatonin. Please consult your doctor for any potential interaction.

Fact Box

Chemical Class

Phenylpiperazines

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Serotonin Antagonist and Reuptake Inhibitors (SARIs)

References

Stahl SM, editor. Trazodone. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 681-85.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1392-94.
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 19 Mar. 2019] (online) Available from:
Trazodone. Sellersville, PA: Teva Pharmaceuticals USA; 1981 [revised Jan. 2014]. [Accessed 19 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Trazonil 25 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Trazonil 25 Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Trazonil Tablet

Benefits of Trazonil Tablet

Side effects of Trazonil Tablet

How to use Trazonil Tablet

How Trazonil Tablet works

All substitutes for Trazonil 25 Tablet

TripAX 25 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Moclobemide (Oral Route)

Domperidone (Oral Route)

Tranylcypromine (Oral Route)

Thioridazine (Oral Route)

Amiodarone (Oral Route)

Frequently asked questions

Is trazodone a mono amine oxidase inhibitor/ selective serotonin reuptake inhibitor/ opiate/ barbiturate/ anti cholinergic/ habit forming/ controlled substance?

Is trazodone taken for anxiety?

Is trazodone taken for sleep or pain?

Does trazodone have sulpha?

Does trazodone cause fluctuation in blood pressure/ diarrhea/ feeling high?

Does trazodone cause anxiety or depression?

Can trazodone be taken with nyquil/ benadryl/ zoloft/ Cymbalta/ valium/ paxil/ flexeril/ melatonin/ xanax?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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