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Traza 25mg Tablet

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 25 Nov 2025 | 03:05 PM (IST)
Traza 25mg Tablet is used in the treatment of depression. This medicine helps by increasing the level of chemical messengers in the brain that relax the nerves and have a calming effect on the brain.
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Traza 25mg Tablet
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General Information

The content is shown in English
Traza 25mg Tablet image
Traza 25mg Tablet image

Product introduction

Traza 25mg Tablet should be taken with food. It is advised to take this medicine at a fixed time each day. You should never skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly as it may worsen your symptoms.

Some common side effects of this medicine include constipation and blurred vision. It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus. Moreover, most of the side effects are immediate and often go away with time. Please consult your doctor if these bother you or do not go away.

Before taking Traza 25mg Tablet, it is important to inform your doctor if you have any history of fits, severe kidney, liver, or heart problems, narrow-angle glaucoma, or any mental disorder. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression if you have any suicidal thoughts.

Uses of Traza Tablet

Benefits of Traza Tablet

Depression
Traza 25mg Tablet is used in the treatment of depression, a mental health condition marked by persistent sadness, lack of interest, and low energy. This medicine helps improve mood, emotional stability, and sleep patterns, thereby enhancing overall quality of life in individuals struggling with depression.

Side effects of Traza Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Traza
  • Vomiting
  • Dizziness
  • Confusion
  • Blurred vision
  • Headache
  • Fatigue
  • Nausea
  • Sleepiness
  • Dryness in mouth
  • Constipation
  • Edema (swelling)
  • Hypotension (low blood pressure)
  • Fainting
  • Drowsiness
  • Nasal congestion (stuffy nose)
  • Weight gain
  • Weight loss
  • Pain

How to use Traza Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Traza 25mg Tablet should be taken with or after food.

How Traza Tablet works

Traza 25mg Tablet modulates the level of serotonin in the brain. Serotonin is a chemical messenger in the brain that helps in regulating the mood.

All substitutes for Traza 25mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • It makes you feel sleepy. Take it in the evening or before you go to bed.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Do not drive or do anything that requires mental focus until you know how Traza 25mg Tablet affects you.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Traza 25mg Tablet
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Traza 25mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Traza 25mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Traza 25mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

SAFE IF PRESCRIBED
Traza 25mg Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.
However, talk to your doctor if you have any underlying kidney disease as this medicine should be used cautiously.
Liver

Liver

CAUTION
Traza 25mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine.

Interaction with drugs

Taking Traza with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Moclobemide (Oral Route)

Do not consume Moclobemide with Trazodone. If Moclobemide is essential, ensure a gap of at least 1 day after discontinuing Trazodone. Please consult your doctor.
Life-threatening

Domperidone (Oral Route)

Do not consume Domperidone with Trazodone.
Life-threatening

Tranylcypromine (Oral Route)

Do not consume Tranylcypromine with Trazodone. If Tranylcypromine is essential, ensure a gap of at least 2 weeks after discontinuing Trazodone. Please consult your doctor.
Severe

Thioridazine (Oral Route)

Do not consume Thioridazine with Trazodone. If concurrent use is essential, watch out for symptoms such as sleepiness, dry mouth, impaired voluntary movements, weight gain, constipation, muscle stiffness or tremors and consult your doctor if you experience them. They may adjust the dose of Thioridazine accordingly. Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Amiodarone (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Frequently asked questions

Trazodone is not a mono amine oxidase inhibitor/ selective serotonin reuptake inhibitor/ opiate/ barbiturate/ anti cholinergic/ habit forming/ controlled substance
Trazodone is taken for anxiety and depression
Trazodone is not prescribed for sleep or pain relief
Trazodone does not have sulpha in it
Trazodone may cause blood pressure fluctuations. It is not known to cause diarrhea/ feeling high
It is given for the treatment of anxiety and depression. Please consult your doctor for any observed side effects
Trazodone cannot be taken with Nyquil/ Benadryl/ Zoloft/ Cymbalta/ valium/ paxil/ flexeril/ Xanax. Trazodone can be taken with melatonin. Please consult your doctor for any potential interaction.

Fact Box

Chemical Class

Phenylpiperazines

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Serotonin Antagonist and Reuptake Inhibitors (SARIs)

References

  1. Stahl SM, editor. Trazodone. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 681-85.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1392-94.
  3. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 19 Mar. 2019] (online) Available from:
  4. Trazodone. Sellersville, PA: Teva Pharmaceuticals USA; 1981 [revised Jan. 2014]. [Accessed 19 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: D D Pharmaceuticals
Address: G-1/583,585,586 Sitapura Industrial Area, RIICO, Tonk Road, Jaipur (Rajasthan)-302022

Vendor Details

Country of origin: India
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