Topirol 50 Tablet


Overview

Introduction

Topirol 50 Tablet is a medicine used to treat epilepsy (seizures) and to prevent migraines. It is also used in the treatment of Lennox-Gastaut syndrome (a rare, but severe form of epilepsy that starts in early childhood).

Topirol 50 Tablet controls seizures by decreasing the abnormal and excessive activity of the nerve cells in the brain. It may be taken with or without food, preferably at the same time, each day. If you have missed a dose, take it as soon as you remember it and finish the full course of treatment even if you feel better. Stopping the medication suddenly without talking to your doctor may cause increased frequency of seizures. Your doctor may advise regular monitoring of serum bicarbonate levels while you are taking this medicine.

Some of the common side effects of this medicine include nausea, taste change, fatigue, diarrhea, weight loss, loss of appetite, and memory impairment. It may also cause vision problems like myopia or glaucoma, so it is important to get your eyesight checked before you start the treatment and regularly thereafter. You may experience dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Please consult your doctor if these side effects bother you or do not go away.

Side effects of Topirol Tablet

Common
  • Dizziness
  • Sleepiness
  • Nausea
  • Taste change
  • Paresthesia (tingling or pricking sensation)
  • Fatigue
  • Diarrhea
  • Weight loss
  • Memory impairment
  • Abdominal pain
  • Loss of appetite
  • Nervousness
  • Speech disorder
  • Psychomotor impairment
  • Visual impairment
  • Fever
  • Numbness
  • Upper respiratory tract infection

How to use Topirol Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Topirol 50 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Topirol Tablet works

Topirol 50 Tablet is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Topirol 50 Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Topirol 50 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Topirol 50 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Topirol 50 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Topirol 50 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Topirol 50 Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Topirol 50 Tablet should be used with caution in patients with liver disease. Dose adjustment of Topirol 50 Tablet may be needed. Please consult your doctor.

What if you forget to take Topirol Tablet?

If you miss a dose of Topirol 50 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Topirol 50 Tablet
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Quick Tips

  • Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
  • Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
  • Some healthy tips to prevent seizures:
    • Practice yoga every day.
    • Get enough sleep at nighttime.
    • Limit the use of screen time such as mobile/laptop.
    • Take your medication on time.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Keep yourself hydrated by drinking plenty of fluids throughout the day while taking Topirol 50 Tablet. This can reduce the risk of kidney stones.
  • Monitor your weight during treatment with this medicine as it can cause weight gain.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Interaction with Drugs

Taking Topirol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Eurolam, Alwel, Tenzo
SERIOUS
Brand(s): Antep, C Lep, Ametol
SERIOUS
Brand(s): Equblam, Zepox, Raipox
SERIOUS
Brand(s): Risure
SERIOUS

Patient Concerns

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Sir my wife suffering from migraine for last 5 years,i had treated in medanta,paras,artemis,AIIMS & SMS IN JAIPUR BUT STILL NO IMPROVEMENT KINDLY HELP ME OR SUGGEST ME
Dr. Vikas Sharma
Neurology
tab topirol 25 mg hs
Migraine. Severe pain in head. I have severe pain in head
Dr. Vikas Sharma
Neurology
do mri brain ; start tab topirol 25 mg hs
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Do you have any questions related to Topirol 50 Tablet ?

User Feedback


FAQs

Q. For how long do I need to take Topirol?

The dose and duration of this medicine will depend on your doctor’s advice. Topirol does not cure your condition (seizures/migraine) but prevents them from occurring. So, you may have to keep taking it for months or years depending on improvement in your symptoms and side effects that may occur.

Q. Is Topirol good for anxiety?

Topirol is not indicated for the treatment of anxiety. Please consult your doctor before taking the medicine.

Q. What are the serious side effects of Topirol?

Serious side effects of Topirol are rare. These serious effects of Topirol may include glaucoma (difficulty in seeing, eye pain and blurred vision), kidney stones (sharp pain in your sides or lower back) and metabolic acidosis (tiredness, loss of appetite, irregular and faint heartbeat). Other serious side effects of Topirol could be suicidal thoughts and insufficient sweating (some children taking Topirol may not sweat enough in hot weather, causing their body temperatures to rise).

Q. I am taking valproic acid for fits. Will Topirol interfere with the working of valproic acid? Can this combination be taken?

Topirol does not interfere with the working of valproic acid, but it increases the risk of getting increased levels of ammonia in blood (hyperammonemia). This can be dangerous. Excess levels of ammonia in blood may cause difficulty in thinking, remembering information, or solving problems. It may decrease your alertness and make you feel very sleepy with low energy. Tell your doctor immediately if you notice these symptoms. In rare cases, hyperammonemia may even occur because of Topirol alone.

Q. Can Topirol be used in children?

Yes, Topirol is used for seizures in children more than 2 years of age. However, because of the lack of any reports, this medicine is not recommended to be used in children for migraine.

Q. Since I have started using Topirol people are saying that I have lost weight. Is it because of Topirol or something else for which I should get investigated?

It could be due to Topirol because Topirol commonly causes weight loss probably due to decrease in appetite. If you still have any doubts, talk to your doctor who will advise you appropriately.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Stahl SM, editor. Topiramate. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 669-73.
  2. McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 601.
  3. Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 12.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1380-82.
  5. Topiramate. High Wycombe, Bucks: Janssen-Cilag Ltd.; 1995 [revised 13 Dec. 2017]. [Accessed 22 Jan. 2019] (online) Available from:External Link
  6. U.S. National Library of Medicine. Topiramate. [Accessed 19 Mar. 2019] (online) Available from:External Link
  7. Topiramate. Gurabo, Puerto Rico: Janssen Ortho; 2012. [Accessed 18 Mar. 2019] (online) Available from:External Link
  8. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
A licensed vendor partner from your nearest location will deliver Topirol 50 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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₹103.2
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