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Ulipristal acetate



Ulipristal acetate is used in adult women of childbearing age to relieve moderate to severe symptoms of uterine fibroids (non-cancerous tumors of the womb) either before the surgery for fibroids or for long term treatment. It is also used as an emergency contraception to prevent pregnancy after unprotected sexual intercourse or known contraceptive failure.

How it works

Ulipristal acetate belongs to a class of drug called selective progesterone receptor modulator. It acts by modifying activity of naturally occurring hormone progesterone and reduces the size of fibroids, reduces bleeding and increases red blood cells count.

Common side effects

Abdominal pain, Dizziness, Pain during periods, Fatigue, Headache, Nausea, Intermenstrual bleeding


Expert advice

• Take ulipristal within the first week of your menstrual period.
• Do not take ulipristal for regular contraception.
• Never stop taking ulipristal acetate without the advice of your doctor even if you feel better, as symptoms may re-occur later.
• Seek medical advice if your menstrual bleeding does not reduce or stop within the first 10 days of treatment with ulipristal acetate.
• Do not drive or operate machinery as ulipristal acetate may cause dizziness.
• Should not be given to patients allergic to ulipristal acetate or any of its ingredients.
• Should not be given to women under 18 years of age.
• Should not be given to females with vaginal bleeding caused due to other than uterine fibroids.
• Should not be given to women who have cancer of the uterus (womb), cervix (the neck of the womb), ovary or breast.
• Should not be given to women with severe asthma treated by oral glucocorticoid.
• Should not be given to pregnant or breastfeeding females.

Frequently asked questions

Ulipristal acetate

Q. Is ulipristal acetate available in India?
Yes, ulipristal acetate is available in India.
Q. Is ulipristal acetate safe?
Ulipristal acetate is safe if taken in recommended dose as prescribed by your doctor. 

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)