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Told 500mg Tablet

Tolbutamide (500mg)
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Told 500mg Tablet is a medicine used to treat type 2 diabetes mellitus in adults. It belongs to a group of medicines called sulfonylureas and helps control blood sugar levels in people with diabetes. This helps to prevent serious complications of diabetes like kidney damage and blindness.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 07 Jan 2026 | 03:31 PM (IST)
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General Information

The content is shown in English
Told 500mg Tablet image
Told 500mg Tablet image

Product introduction

Told 500mg Tablet may be used by itself or along with other medicines. It should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working.

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effects of taking this medicine include nausea, headache, and dizziness. It can also sometimes cause low blood glucose levels (hypoglycemia). Make sure you recognize the signs of having low blood glucose levels, such as sweating, dizziness, headache, and shaking, and know how to deal with it. To prevent this, it's important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. Some people may find that they put on weight with this medicine.

You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease, thyroid disease, or some hormonal conditions. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

Uses of Told Tablet

Benefits of Told Tablet

Type 2 diabetes mellitus
Type 2 diabetes is a condition where the body either does not produce enough insulin or does not use it properly, leading to high blood sugar levels. Told 500mg Tablet helps lower blood sugar by increasing the release of insulin from the pancreas. This helps control blood sugar levels and prevents complications related to diabetes.

Side effects of Told Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Told
  • Nausea
  • Headache
  • Dizziness
  • Hypoglycemia (low blood glucose level)

How to use Told Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Told 500mg Tablet should be taken with or after food.

How Told Tablet works

Told 500mg Tablet is an antidiabetic medication. It works by increasing the amount of insulin released by the pancreas in order to lower blood glucose.

All substitutes for Told 500mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Take it shortly before or with the first main meal of the day (usually breakfast). Avoid skipping meals.
  • Be careful while driving or operating machinery until you know how Told 500mg Tablet affects you.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxiety.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
  • Told 500mg Tablet helps decrease high blood sugar level and avoid long-term complications of diabetes.
  • Take it shortly before or with the first main meal of the day (usually breakfast). Avoid skipping meals.
  • Exercise regularly, eat a healthy diet and take your other diabetes medicines (if prescribed) alongside.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxiety.
  • Monitor your blood sugar level regularly while you are taking this medicine. 
  • Be careful while driving or operating machinery until you know how Told 500mg Tablet affects you.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Told 500mg Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Told 500mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Told 500mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Monitor the breastfed baby’s blood sugar during treatment with Told 500mg Tablet
Driving

Driving

CAUTION
Told 500mg Tablet may affect your driving ability if your blood sugar becomes too low or too high. Monitor your blood glucose and avoid driving if affected.
Kidney

Kidney

UNSAFE
Told 500mg Tablet is unsafe to use in patients with kidney disease and should be avoided.
Use of Told 500mg Tablet is not recommended in patients with severe kidney disease.
Liver

Liver

UNSAFE
Told 500mg Tablet is unsafe to use in patients with liver disease and should be avoided.
Use of Told 500mg Tablet is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Told with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Disopyramide (Oral Route)

If concurrent use is essential, watch out for symptoms such as confusion, headache, nausea, dizziness or faintness and consult your doctor if you experience them.
Moderate

Mifepristone (Oral Route)

Watch out for symptoms of Tolbutamide side effects such as nausea, headache, dizziness or fatigue and consult your doctor if you experience them. They may adjust the doses as per the observations. Mifepristone may raise blood levels of Tolbutamide.
Moderate

Linagliptin (Oral Route)

Monitor your blood glucose levels regularly during the simultaneous use of these medicines.
Moderate

Asparaginase (Injection Route)

Your doctor may monitor your diabetic control closely and adjust the doses as per the observations.
Moderate

Pioglitazone (Oral Route)

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your liver function.

Frequently asked questions

Told 500mg Tablet does not affect kidneys in patients with normal kidney function. However, its use should be avoided in patients with severe kidney disease since Told 500mg Tablet is principally eliminated by the kidneys.
Told 500mg Tablet should be avoided by patients who are allergic to it, have severe kidney or liver disease, have G6PD-deficiency (an inherited condition affecting red blood cells), or are due to have surgery. Along with that, patients who are trying to get pregnant, are pregnant, or breastfeeding, or have insulin-dependent diabetes (type 1 diabetes mellitus) should also avoid taking Told 500mg Tablet.
Told 500mg Tablet takes about 2 to 3 hours to reduce blood sugar levels. You may not feel any difference, but this does not mean it is not working. So, continue the medication as directed by your doctor and if you have any concerns, discuss it with your doctor.
Told 500mg Tablet should be used with extra caution in elderly patients because they are at high risk of getting low blood sugar (hypoglycemic event).
The Told 500mg Tablet is not used for the management of prediabetes, a condition with blood glucose levels higher than normal but not high enough to label you as diabetic. There are clinical studies available, but the evidence is not strong enough for its use in prediabetes.
Both Told 500mg Tablet and teneligliptin are antidiabetic medicines and control blood sugar levels effectively. However, they work in different ways and have a different mechanism of action and side effects. Told 500mg Tablet commonly causes hypoglycemia and weight gain while teneligliptin causes headache and nasopharyngitis. Teneligliptin causes hypoglycemia when used along with insulin or sulfonylureas and does not cause weight gain.
Use of Told 500mg Tablet should be avoided if you are allergic (hypersensitive) to sulfonylureas or sulfonamides or any of the other ingredients of this medicine.
Yes, Told 500mg Tablet can cause weight gain. It is advisable to closely monitor your diet and do regular exercise while taking this medicine. Avoid skipping your meals as it can cause very low blood sugar levels and you may end up snacking or taking a lot of sugars.
Told 500mg Tablet, when used with insulin, can help to control high blood sugar levels. Taking them together can help to lower the dose of insulin but there could also be an increased risk of hypoglycemia (low blood sugar levels). Dose of these medicines may need to be adjusted along with regular blood sugar level monitoring. Please consult your doctor if you have any doubts and follow your doctor's instructions carefully to get maximum benefit of Told 500mg Tablet.
No, Told 500mg Tablet is not a Thiazolidinedione, it is a sulfonylurea. However, both are antidiabetic medicines but belong to a different group of medicines.
Told 500mg Tablet is not advised to be used for the management of gestational diabetes. Use of Insulin is advised during pregnancy to control the blood glucose levels. However, do not start taking Told 500mg Tablet without otherwise prescribed by the doctor.
No, hair loss is not seen with the use of Told 500mg Tablet. However, diabetes itself can lead to hair loss. Talk to your doctor if you have excessive hair loss as it could be due to some other underlying condition or it could be a sign of your diabetes getting worsened.
Yes, it is safe to take Told 500mg Tablet with Pioglitazone in patients with diabetes mellitus. Together they can control your blood sugar levels, lower plasma lipid levels and improve blood pressure. However, the risk of very low blood sugar levels can increase and the dose of these medicines may need to be adjusted.

Fact Box

Chemical Class

Benzenesulfonamides

Habit Forming

No

Therapeutic Class

ANTI DIABETIC

Action Class

Sulfonylureas (Insulin Secretagogues)

References

  1. Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1255-1257.
  2. Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 738.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1375-76.
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 13 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Lotus Life Sciences
Address: lls, lakshmi nilayam, ravindranagar, nacharam, hyderabad - 500076

Vendor Details

Country of origin: India
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