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Linagliptin

INFORMATION

Uses

Linagliptin is used in the treatment of type 2 diabetes.

How it works

Linagliptin increases the amount of insulin released by the pancreas in order to lower the blood glucose.

Common side effects

Pancreatic inflammation, Angioedema (swelling of deeper layers of skin), Urticaria, Constipation, Cough, Fall in blood sugar level, Rash

AVAILABLE MEDICINE

Expert advice

Do not start or continue linagliptin and consult your doctor: 
  • If you are allergic to linagliptin or to any medicine from the same group (DPP-4 inhibitors).
  • If you have type 1 diabetes or if you have serious complication of diabetes where high levels of blood acids called ketones are produced in your body (diabetic ketoacidosis).
  • If you are taking insulin or other antidiabetic drug known as a sulphonylurea, your doctor may reduce the dose of your medicines, as it may otherwise cause excessively low blood glucose (hypoglycemia).
  • If you are already being treated with insulin (medicine to lower blood sugar levels) and have severe kidney disease.
  • If you have/had a disease of the pancreas.
  • Do not substitute it with insulin, if you are on insulin.

Frequently asked questions

Linagliptin

Q.Is linagliptin better than sitagliptin?
Linagliptin and sitagliptin belong to same class of drugs (DPP-4 inhibitor) with similar action, but their effect may vary upon individual response

Q.Is linagliptin available in India?
Yes, linagliptin is available in India with brand name as Trajenta

Q.Is linagliptin generic?
Linagliptin is generic name; however, linagliptin is not available in a generic form

Q.Is linagliptin safe?
Linagliptin is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Q.How is linagliptin excreted?
Linagliptin is mainly excreted in stools and less in urine

Q.What is linagliptin and for which treatment used for?
Linagliptin belongs to a group of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors, and used in addition to diet and exercise for the treatment of type-2 diabetes.


Content on this page was last updated on 24 November, 2016, by Dr. Varun Gupta (MD Pharmacology)