Tofza Tablet

Prescription Required
SALT COMPOSITION
Storage
Store below 30°C
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Introduction

Tofza Tablet is used to treat moderate to severe rheumatoid arthritis. It helps decrease pain, tenderness, and swelling in the joints by reducing inflammation. It also helps slow the progression of bone and joint damage.

Tofza Tablet may be prescribed by itself or in combination with another medicine. The tablets can be taken with or without food and it is best to take them at the same time each day. Your dose will depend on your condition and what other medicines you are taking. You should use it as your doctor tells you to. Do not stop taking this medicine unless your doctor tells you to because your condition could get worse.

The most common side effects of Tofza Tablet include upper respiratory tract infections, headache, diarrhea, and nasopharyngitis. There are other less common side effects, some of them serious, including blood clots and tears in the stomach or intestine wall. These need urgent medical attention. If you have any worries about side effects, talk to your doctor.

You may need blood tests before you are given this medicine and you should not start taking it if you have any kind of infection. Make sure you talk to your doctor before starting treatment if you have or have ever had, tuberculosis, shingles, kidney or liver disease, hepatitis B or C, or blood clots in your legs or lungs. Tofza Tablet can make you more likely to get infections or may worsen any current infections so avoid contact with people who have things you might catch (such as chickenpox, measles, flu). This medicine is not suitable for children under 18 years old and you should not use it if you are pregnant or breastfeeding, unless your doctor feels the benefit is greater than the risk. Your doctor may need to examine you regularly.

Uses of Tofza Tablet

Benefits of Tofza Tablet

In Rheumatoid arthritis

Tofza Tablet works by blocking the action of some chemicals which cause inflammation. It can help reduce pain, stiffness, and swelling in your joints and slow down the progression of bone and joint damage. This will help you do normal daily activities more easily and thus improve your quality of life. This medicine should be taken at the same time each day to get maximum benefits. Keep taking the medicine even if you feel well because it is preventing future harm as well as improving your symptoms.

Side effects of Tofza Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tofza

  • Upper respiratory tract infection
  • Headache
  • Diarrhea
  • Nasopharyngitis (inflammation of the throat and nasal passages)

How to use Tofza Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tofza Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Tofza Tablet works

Tofza Tablet is a Janus kinase inhibitor. It works by blocking the action of the enzyme, Janus kinase. This decreases inflammation and joint damage in rheumatoid arthritis.

Safety advice

Alcohol
SAFE
Consuming alcohol with Tofza Tablet does not cause any harmful side effects.
Pregnancy
CONSULT YOUR DOCTOR
Tofza Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Tofza Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
SAFE
Tofza Tablet does not usually affect your ability to drive.
Kidney
CAUTION
Tofza Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Tofza Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Tofza Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Tofza Tablet may be needed. Please consult your doctor.

What if you forget to take Tofza Tablet?

If you miss a dose of Tofza Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips

  • Tofza Tablet is used alone or in combination with other medicines for the treatment of rheumatoid arthritis, that did not improve with other anti-rheumatic drugs.
  • It may take take 3 to 6 months to feel the maximum effect of this medication. Keep taking it as prescribed.
  • Your doctor may get regular blood tests done to monitor your liver function, kidney function, blood counts, or cholesterol levels.
  • Tofza Tablet can make it a bit harder for people to fight off infections. Inform your doctor if you have symptoms of an infection such as fever, chills, cough, and muscle aches.
  • Your doctor may get TB (tuberculosis) skin test and a chest X-ray before starting treatment with this medication.
  • Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Fact Box

Chemical Class
Pyrrolo Pyrimidine Derivative
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
Janus kinase inhibitors

Patient concerns

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I have joint pain in my rt wrist since 6 yrs. What are the possible reasons?
Dr. Trilok Kumar Jha
Orthopaedics
It may be Tenosynovitis, or Rheumatoid arthritis or any other type of arthritis
Sir/Ma'am, I feel pain in the heel of both the legs especially when I get up from the bed in the morning. After walking couple of steps, it goes away. there is no bone problem reported in the Xray report. Please guide me what could be the reason?
Dr. Mehtab Baig
Orthopaedic Physiotherapy
This is the test for rheumatoid arthritis
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FAQs

Q. Can I take Tofza Tablet if I have liver problems?

Inform your doctor if you have liver problems, before starting Tofza Tablet. This is done because in some cases Tofza Tablet may cause an increase in liver enzymes. Therefore, your liver function needs to be investigated before starting Tofza Tablet. Although, Tofza Tablet can be given to patients with mild to moderate liver function impairment, but should not be prescribed to patients with severe liver impairment.

Q. Can Tofza Tablet cause cancer?

Tofza Tablet may increase the chances of developing the risk of certain cancers (lymphoma and other cancers including skin cancers) by affecting the working of the immune system. Hence, inform your doctor if you ever had or have any type of cancer.

Q. What is Tofza Tablet used for?

Tofza Tablet is approved for use in people with moderate to severe rheumatoid arthritis. It is an inflammatory disease of the joints. It is used if previous therapy did not work well or did not suit the patient. However, it can also be used earlier in treatment if the person does not respond well to the prescribed drugs. It can be used alone or together with some other medicines, such as methotrexate.

Q. How long does it take for Tofza Tablet to start working?

Tofza Tablet usually takes about 2 to 8 weeks before you start feeling better, and it can take 3 to 6 months to feel the maximum effect of this medication.

Q. Do I need to get any investigations done before starting Tofza Tablet?

You may need to get your blood tests done before you start Tofza Tablet or while you are taking it. Blood tests are done in order to check if you have a low red blood cell count (anemia), low white blood cell count (neutropenia or lymphopenia), high blood fat (cholesterol) or high levels of liver enzymes. It also helps to ensure that treatment with Tofza Tablet is not causing problems. In addition to this, your doctor may advise you to get tested for tuberculosis before starting Tofza Tablet, as using Tofza Tablet may make an existing infection worse.

Q. Can Tofza Tablet cause infections?

Tofza Tablet is a medicine that affects your immune system. This may reduce your ability to fight infection and may increase the risk of getting a serious infection including tuberculosis. It may also include infections caused by severe fungal, bacterial or viral infections that spread through the body. In some cases, these infections can be life-threatening and may even cause death. Hence, it is advised to treat these infections in a hospital.

Q. If I am already taking tocilizumab, can I take Tofza Tablet?

No, you should not take tocilizumab along with Tofza Tablet. Tofza Tablet affects the immune system, so you should avoid taking it with any other immunity-affecting medicine. Taking both medicines together can further increase the risk of infection and may lead to further complications.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1373-74.
  2. Drugs.com. Tofacitinib. [Accessed 02 Apr. 2019] (online) Available from:External Link
  3. Tofacitinib. New York, New York: Pfizer Labs; 2012 [revised Nov. 2012]. [Accessed 02 Apr. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer address

Wallace Pharmaceuticals Pvt. Ltd., 3rd Floor, Dempo Trade Centre Bldg., Patto Plaza, EDC Complex, Panaji 403001, Goa, India.
Country of origin: India

Expires on or after: December, 2021

A licensed vendor partner from your nearest location will deliver Tofza Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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