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17 Nov 2020 | 10:16 AM (IST)
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Sorafenat 200mg Tablet

Prescription Required
Manufacturer
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)

Introduction

Sorafenat 200mg Tablet belongs to the class of medicines known as tyrosine kinase inhibitors used in the treatment of liver cancer, kidney cancer, and thyroid cancer.

Sorafenat 200mg Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Fatigue, nausea, loss of appetite, hair loss and diarrhea are some common side effects of this medicine. It might cause high blood pressure, so the doctor may ask you for a regular check-up of blood pressure. You must inform your doctor if you notice severe skin reaction such as skin rash, or any pain, swelling, and redness of your hands and feet.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or high blood pressure. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Benefits of Sorafenat Tablet

In Liver cancer

Liver cancer is the cancer that develops in the cells of the liver called hepatocytes. There may be no symptoms present in the early stages of the cancer but as the disease advances to later stages symptoms such as weight loss, stomach pain, vomiting and yellowed skin. Sorafenat 200mg Tablet kills the cancer cells and prevents further growth and spread of cancer to other unaffected areas. Follow your doctor’s instructions carefully and do not drink alcohol or smoke. Alcohol intake or smoking can worsen your condition and hinder your recovery.

In Kidney cancer

Sorafenat 200mg Tablet is used to treat kidney cancer and its associated symptoms such as blood in the urine, unexplained low back pain or weight loss, fatigue, loss of appetite, etc. It stops cancer growth and prevents multiplication of cancer cells. This restricts the advancement of cancer to other unaffected regions. You need to follow your doctor’s instructions very carefully to recover.

In Thyroid cancer

Thyroid is a butterfly-shaped gland located at the base of your neck. Your thyroid produces hormones that regulate your heart rate, blood pressure, body temperature and weight. Thyroid cancer occurs in the cells of the thyroid and it might not cause any symptoms at first. Sorafenat 200mg Tablet restricts the oxygen supply of the cancer cells and stops its growth as well as further spread. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.

Side effects of Sorafenat Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sorafenat

  • Fatigue
  • Nausea
  • Loss of appetite
  • Diarrhea
  • Abdominal pain
  • Hair loss
  • Weight loss
  • Rash
  • Painful blisters on hands and feet

How to use Sorafenat Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sorafenat 200mg Tablet is to be taken empty stomach.

How Sorafenat Tablet works

Sorafenat 200mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Sorafenat 200mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Sorafenat 200mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
UNSAFE
Sorafenat 200mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
SAFE
Sorafenat 200mg Tablet does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Sorafenat 200mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Sorafenat 200mg Tablet is recommended.
Regular monitoring of blood tests may be advised while you are taking this medicine.
Liver
CAUTION
Sorafenat 200mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Sorafenat 200mg Tablet may be needed. Please consult your doctor.

What if you forget to take Sorafenat Tablet?

If you miss a dose of Sorafenat 200mg Tablet, skip it and continue with your normal schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Sorafenat 200mg Tablet
₹74.0/Tablet
₹56.43/Tablet
save 24%
Nexavar 200mg Tablet
Bayer Pharmaceuticals Pvt Ltd
₹2433.96/Tablet
3189% costlier

Quick Tips

  • Sorafenat 200mg Tablet is used in the treatment of liver, kidney, and thyroid cancer.
  • Take it without food, or with a low fat meal and a full glass of water.
  • Take it at the same time everyday to maintain consistent levels in your body.
  • Women who could get pregnant should use a reliable method of contraception to prevent pregnancy while taking this medicine.
  • Your doctor may regularly monitor your blood pressure while you are taking this medicine.
  • Inform your doctor if you get a skin rash, or any pain, swelling, and redness of your hands and feet while you are taking this medicine.
  • Do not change the dose or discontinue use without consulting your doctor.

Fact Box

Chemical Class
Diarylethers Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS

Patient Concerns

arrow
Hello sir, Plz help me to find out whether im really having thyroid cancer or not. I have taken two consultation from different doctors, one is saying she got hypothyroid or something, and she is taking medicines from that doctor, it's been 3months i guess now.( Homeopathy) another doctor saying negative, like she has no problem at all, We dont know what to, we should continue taking medicines or not Plz help me out asap. Thank you
Dr. Vijay Verma
ENT
there is no cancereven thyroid level is normal
Sir my brother have skin cancer can you do something for save his life ??
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Treatment of cancer depends on whether it is localized or metastatic cancer
arrow
Do you have any questions related to Sorafenat 200mg Tablet ?

User Feedback


FAQs

Q. How is Sorafenat 200mg Tablet administered?

Sorafenat 200mg Tablet is an oral medicine and you should take it exactly as per your doctor’s advice. It can be taken without food or with low to moderate fat meal. It should not be taken with high-fat meal which will make Sorafenat 200mg Tablet less effective. If you are taking high-fat meal, take Sorafenib 1 hour before or two hours after high-fat meal.

Q. For how long do I need to take Sorafenat 200mg Tablet?

If Sorafenat 200mg Tablet suits you well, then you should continue taking it for the duration suggested by the doctor. However, if you experience any side effect that bothers you, talk to your doctor immediately.

Q. Do I need to take a treatment along with Sorafenat 200mg Tablet for it to work?

Sorafenat 200mg Tablet is used as a monotherapy, that is, it is a medicine which is used alone rather than in combination with other treatments like radiotherapy or chemotherapy.

Q. How do I know if I am responding to Sorafenat 200mg Tablet?

While receiving treatment with Sorafenat 200mg Tablet, your doctor will most likely recommend regular scans to monitor the size of the tumor. You may also need to get regular blood tests to see if the deranged liver or kidney functions have improved or not.

Q. What are the serious side effects that can occur while taking Sorafenat 200mg Tablet?

The possible serious side effects that may occur (not in everyone) include heart attack and heart failure, increased risk of bleeding, high blood pressure, skin problems and wound healing problems. Some other side effects which get highlighted when you go through various tests are decreased blood flow to the heart, swelling of the liver, an opening in the wall of stomach or intestines (perforation), changes in electrical activity of the heart (QT prolongation) and changes in thyroid hormone levels.

Q. Does Sorafenat 200mg Tablet affect blood sugar levels?

Yes, Sorafenat 200mg Tablet can cause a decrease in the blood sugar levels. In fact, the levels can decrease to the extent that the patient may faint. So, it is important that the patients having diabetes check their blood sugar levels regularly. Additionally, you should also consult the doctor if the dose of anti-diabetic medicines needs to be adjusted.

Q. I have developed redness and pain in my palms and soles ever since I started using Sorafenat 200mg Tablet. My skin is also coming off. Is this dangerous? What should I do?

It seems you have developed hand and foot skin reaction due to Sorafenat 200mg Tablet. Consult your doctor who will either interrupt your therapy for sometime or change your dose. He might also suggest some cream or lotion to treat the problem. If the problem is severe, consult a skin doctor.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1740.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 955.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1274-75.
  4. Sorafenib. Emeryville, California: Onyx Pharmaceuticals, Inc.; 2005 [revised Oct. 2010]. [Accessed 24 Jan. 2019] (online) Available from:External Link
  5. Sorafenib tosilate. Reading, Berkshire: Bayer Plc.; 2006 [revised Jun. 2018]. [Accessed 27 Mar. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Expires on or after: February, 2021

A licensed vendor partner from your nearest location will deliver Sorafenat 200mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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₹7548
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120 tablets in 1 bottle
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