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Sorafenib is used in the treatment of liver cancer, kidney cancer and thyroid cancer.

How it works

In patients with cancer, a change in DNA (genetic material) triggers a signal which produces abnormal cancer cells. Sorafenib blocks this signal, and thus stops the production of these cancer cells.

Common side effects

Fatigue, Nausea, Loss of appetite, Diarrhoea, Abdominal pain, Hair loss, Weight loss, Rash, Hand-foot syndrome

Available Medicine

  • ₹8880
    Natco Pharma Ltd
    1 variant(s)
  • ₹1710
    Cipla Ltd
    1 variant(s)
  • ₹233692
    Bayer Pharmaceuticals Pvt Ltd
    1 variant(s)

Expert advice

  • Inform the doctor if you are suffering from high blood pressure, bleeding problems, chest pain, heart problems (prolongation of QT interval), kidney problems other than kidney cancer, or liver disease; if you are going to have a surgery or have been recently operated upon.
  • Seek immediate medical attention if you experience chest pain, severe dizziness, fainting, sweating or shortness of breath, blood in your urine or stools, abnormal vaginal bleeding, severe stomach pain, coughing up blood, or any bleeding that will not stop while receiving treatment with Sorafenib.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding, sorafenib may decrease fertility in men and women.
  • You may need frequent monitoring of fluid balance and electrolytes if you are at risk of renal dysfunction; monitoring of blood calcium levels and thyroid hormones if you are suffering from thyroid cancer.

Frequently asked questions



Is sorafenib effective in chemotherapy?
Sorafenib is effective in chemotherapy of liver, kidney and thyroid cancer


Is sorafenib cytotoxic?
Sorafenib is a cytotoxic agent


How is sorafenib taken/administered?
Sorafenib is administered orally in the form of two tablets of 200 mg twice a day (total daily dose of 800 mg) on empty stomach at least 1 hour before or 2 hours after eating

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What does sorafenib target?
Sorafenib targets the cancer cells to stop their growth and proliferation.

Content on this page was last updated on 05 April, 2017, by Dr. Varun Gupta (MD Pharmacology)