Information about Ranolazine

Ranolazine Uses

Ranolazine is used to prevent Angina (heart-related chest pain).

How Ranolazine works

Ranolazine is an anti-anginal medication. It works by decreasing the oxygen requirement of the heart by relaxing heart muscle.

Common side effects of Ranolazine

Nausea, Vomiting, Headache, Dizziness, Constipation, Weakness
Written By
Reviewed By
MD (Pharmacology), MBBS
Last updated:
18 Feb 2020 | 11:51 AM (UTC)
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Available Medicine for Ranolazine

RanozexSun Pharmaceutical Industries Ltd
140 to ₹1703 variant(s)
RanolazTorrent Pharmaceuticals Ltd
151 to ₹2362 variant(s)
RancadLupin Ltd
143 to ₹2153 variant(s)
RanxTorrent Pharmaceuticals Ltd
199 to ₹2232 variant(s)
RancvMSN Laboratories
96 to ₹1562 variant(s)
RanopillIntas Pharmaceuticals Ltd
1271 variant(s)
RolazinMacleods Pharmaceuticals Pvt Ltd
1252 variant(s)
CartinexMicro Labs Ltd
1281 variant(s)
CarozaZydus Cadila
1201 variant(s)
AngiotecOaknet Healthcare Pvt Ltd
911 variant(s)

Expert advice for Ranolazine

  • It should be taken with food to avoid stomach upset.
  • It improves HbA1c and blood sugar levels in diabetes patients.
  • It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Notify your doctor if you are taking any other medications along with Ranolazine
  • It may produce changes in the ECG (QTc interval prolongation). It is recommended to get an ECG done within 1 to 2 weeks of starting the medication.

Frequently asked questions for Ranolazine


Q. What are the serious side effects of Ranolazine?

Ranolazine may cause changes in electrical activity of heart which is known as QT prolongation. Your doctor may get regular tests done to check the electrical activity of your heart. Tell your doctor right away if you feel faint, lightheaded or if your heart starts beating irregularly or fast, as these may be symptoms of QT prolongation. Ranolazine may also cause kidney failure in patients who already have kidney problems. Therefore, your doctor may need to do tests to check how your kidneys are working.

Q. I started taking Ranolazine about a week ago. Now I have noticed that my urine has become very dark though I am taking plenty of fluids. Is there anything to worry about?

Urine discoloration could be because of Ranolazine. You need not worry if you do not have any other symptoms. However, if it still bothers you, you can talk to your doctor who will advise you further.

Q. In case I accidentally take excess of Ranolazine, what will happen?

Excess of Ranolazine can cause nausea, vomiting, lightheadedness, double vision, tiredness, severe tremor, confusion, hallucinations, difficulty in speaking and walking and you can even faint. If you have taken excess of Ranolazine by mistake, call your doctor right away or seek emergency medical care in a nearby hospital.

Q. Is it safe to take Ranolazine if I am already taking metoprolol?

Yes, it is safe to take the Ranolazine and Metoprolol together. Ranolazine has minimal effect on blood pressure in patients of angina.

Q. I am a diabetic and am taking metformin. My doctor has prescribed Ranolazine, is it safe to take both together?

If you are taking metformin along with Ranolazine, you have to be careful since Ranolazine may increase the levels of metformin in the body which can lead to metformin toxicity. Talk to your doctor who will modify the dose of metformin.

Q. I have been taking simvastatin to keep my cholesterol levels in check. Can I take Ranolazine with it?

It is recommended not to take simvastatin and Ranolazine together because it may cause simvastatin toxicity which may lead to symptoms like muscle weakness and soreness, fatigue, decreased urination, etc. Let your doctor know that you are already taking simvastatin. If it is still necessary to take, then take it exactly as advised by the doctor.


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