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Raf 50mg Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 26 Nov 2025 | 12:32 PM (IST)
Raf 50mg Tablet is used in the treatment of ulcers in the stomach and intestine. It contains the active ingredient sucralfate which promotes the healing of ulcers by forming a coating over them which acts as a physical barrier.
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General Information

Contains

Sucralfate (50mg)

Marketer

Zest Pharma

Storage

Store below 30°C
The content is shown in English
Raf 50mg Tablet image
Raf 50mg Tablet image

Product introduction

Raf 50mg Tablet is taken one hour before meals preferably at bedtime in the dose and duration advised by the doctor. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen.

The most common side effect of Raf 50mg Tablet are constipation and headache. To prevent constipation, take plenty of fluids while on treatment with this medicine. Dizziness and sleepiness may occasionally occur, so do not drive or do anything that requires mental focus until you know how this medicine affects you.

Before taking Raf 50mg Tablet inform the doctor if you are suffering from any liver or kidney disease. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine. Do not take antacids within two hours of taking Raf 50mg Tablet.

Uses of Raf Tablet

Benefits of Raf Tablet

Treatment of Intestinal ulcers
Intestinal ulcers are painful sores that develop in the inner lining of the intestine. Raf 50mg Tablet is used to treat intestinal ulcers. Raf 50mg Tablet works by reducing the amount of acid your stomach makes, preventing further damage to the ulcer, and heals naturally. Raf 50mg Tablet also reduces pain and bleeding associated with intestinal ulcers. You may be given other medicines along with this medicine depending on what caused the ulcer. You need to keep taking Raf 50mg Tablet as prescribed by the doctor for it to be effective, even if the symptoms seem to disappear.
Treatment of Stomach ulcers
Stomach ulcers are painful sores that develop in the inner lining of the stomach. Raf 50mg Tablet is used to treat stomach ulcers. Raf 50mg Tablet covers the damaged ulcer tissue in the stomach and protects it against stomach acid or further injury. This helps ulcers heal more quickly. $also gives relief from pain and discomfort in the stomach associated with stomach ulcers. You need to keep taking the medicine as it is prescribed for it to be effective, even if the symptoms seem to disappear.

Side effects of Raf Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Raf
  • Constipation

How to use Raf Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Raf 50mg Tablet is to be taken on an empty stomach.

How Raf Tablet works

Raf 50mg Tablet forms a coating over the ulcer or any other raw surface. This creates a physical barrier that protects the ulcer/raw surface from the gastric acid or any other injury, allowing it to heal.

Quick tips

  • Take it on an empty stomach, preferably 1 hour before a meal.
  • Do not take antacids 30 minutes before or after taking this medication.
  • Use caution while driving or doing anything that requires concentration, as Raf 50mg Tablet can cause dizziness and sleepiness.
  • It may take 4-6 weeks or more for the ulcers to heal completely. Do not stop taking the medicine until your doctor tells you to.
  • Inform your doctor if you have a kidney disorder.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Raf 50mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Raf 50mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Raf 50mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Raf 50mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Raf 50mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Raf 50mg Tablet in patients with liver disease.

Interaction with drugs

Taking Raf with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Ofloxacin (Oral Route)

Ensure a gap of at least 2 hours between taking Ofloxacin and Sucralfate. Your doctor may monitor your treatment and adjust the doses as per the observations.
Moderate

Norfloxacin (Oral Route)

Ensure a gap of at least 2 hours between taking Norfloxacin and Sucralfate. Your doctor may monitor your treatment and adjust the doses as per the observations.
Moderate

Levofloxacin (Oral Route)

Ensure a gap of at least 2 hours between taking Levofloxacin and Sucralfate. Your doctor may monitor your treatment and adjust the doses as per the observations.
Moderate

Ciprofloxacin (Oral Route)

Keep a gap of at least 2 hours to avoid any interaction. Sucralfate may reduce blood levels of Ciprofloxacin.
Moderate

Amitriptyline (Oral Route)

To take Amitriptyline, ensure a gap of at least 2 hours before or after taking Sucralfate.

Frequently asked questions

It is advisable to avoid taking antacids within 30 minutes of taking Raf 50mg Tablet since this medicine can decrease the absorption of some antacids if taken together.
Raf 50mg Tablet must be taken on an empty stomach, at least 1 hour before or 2 hours after a meal.
No, it takes around one to two weeks for the medicine to heal an ulcer of the stomach or intestine. But continue taking Raf 50mg Tablet for the duration as prescribed by your doctor for complete healing.
Yes, constipation is one of the common side effects of Raf 50mg Tablet. Include fiber in your diet (fruits and vegetables), drink 8-10 glasses of fluids a day, and keep active. A stool softener (with a doctor's prescription) once or twice a day may prevent constipation. If you do not have a bowel movement for 2-3 days, consult your doctor.
Raf 50mg Tablet is not an antibiotic/sulfa drug/ PPI (proton-pump inhibitor) or a pain-killer. It is an ulcer protective medicine
No. Raf 50mg Tablet is a prescription drug. It is not available or sold over the counter
Yes. Raf 50mg Tablet is gluten free. However, please refer to package insert of the prescribed brand before use
Yes. Raf 50mg Tablet is relatively safe if used as recommended. In case of any side-effects, consult your doctor
Yes. Raf 50mg Tablet can be taken with Prilosec/Nexium/ Tylenol/Zantac/ibuprofen and Pepto if prescribed by your doctor
Raf 50mg Tablet does not cause headaches/weight gain/insomnia or heartburn. If you experience any such symptoms, please consult your doctor
No. Raf 50mg Tablet is not a narcotic drug.

Fact Box

Chemical Class

Polysaccharide derivative

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Anti-Ulcerants

Related lab tests

Anti Saccharomyces Cerevisiae (ASCA), IgA

Anti Saccharomyces Cerevisiae (ASCA), IgG

Helicobacter Pylori IgA

Helicobacter Pylori IgG

Helicobacter Pylori IgM

References

  1. Wallace JL, Sharkey KA. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1315.
  2. McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 1075-76.
  3. Sucralfate. Bridgewater, NJ: Aptalis Pharma US; Mar. 2013. [Accessed on 28 Mar. 2019] (online) Available from:
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Sucralfate. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
  6. Sucralfate [Drug Label]. Irvine, CA: Allergan USA, Inc.; 2017. [Accessed 06 Apr. 2024] (online) Available from:
  7. Sucralfate. Prescribing information. Mylan Institutional Inc., Rockford; USA; 2025. [Accessed 11 Sep. 2025] (online) Available from:
  8. Sucralfate [Drug Label]. North Wales, PA: Teva Pharmaceuticals; 2025. [Accessed 08 Nov. 2025] (online). Available from:
  9. Antepsin. Paris, France: Chugai Pharma France; 2010. [Accessed 12 Nov. 2025] (online). Available from:
  10. Sucralfate [Drug Label]. North Wales, PA: Teva Pharmaceuticals; 2025. [Accessed 08 Nov. 2025] (online). Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zest Pharma
Address: 201, Navneet Darshan, 3rd Floor, 16/2 Old Palasia, Indore - 452001, Madhya Pradesh, INDIA

Vendor Details

Country of origin: India

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