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Sucralfate is used in the treatment of intestinal ulcers and stomach ulcers.

How it works

Sucralfate forms a coating over the ulcer or any other raw surface. This creates a physical barrier that protects the ulcer/raw surface from the gastric acid or any other injury, allowing it to heal.

Common side effects


Available Medicine

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Expert advice

  • Do not take the Sucralfate at least 2 hours before or after taking other medicines. It may interact with these other medicines
  • Take Sucralfate on an empty stomach, preferably 1 hour before a meal.
  • Avoid taking antacids, before or after 30 minutes of taking a dose of Sucralfate.
  • Notify your doctor if you have a kidney disorder, as it may put you at a greater risk of developing aluminum overload.
  • Notify your doctor, if you are or planning to become pregnant.

Frequently asked questions



Is sucralfate an antibiotic/sulfa drug/pain-killer/PPI?
Sucralfate is not an antibiotic/sulfa drug/ PPI (proton-pump inhibitor) or a pain-killer. It is an ulcer protective medicine


Is sucralfate available or sold over the counter?
No. Sucralfate is a prescription drug. It is not available or sold over the counter


Is sucralfate gluten free?
Yes. Sucralfate is gluten free. However, please refer to package insert of the prescribed brand before use

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Is sucralfate safe?
Yes. Sucralfate is relatively safe if used as recommended. In case of any side-effects, consult your doctor


Can I take sucralfate with Prilosec/Nexium/ Tylenol/Zantac/ibuprofen/Pepto?
Yes. Sucralfate can be taken with Prilosec/Nexium/ Tylenol/Zantac/ibuprofen and Pepto if prescribed by your doctor


Does sucralfate cause headaches/weight gain/insomnia/ heartburn?
Sucralfate does not cause headaches/weight gain/insomnia or heartburn. If you experience any such symptoms, please consult your doctor


Is sucralfate a narcotic drug?
No. Sucralfate is not a narcotic drug.

Content on this page was last updated on 10 April, 2017, by Dr. Varun Gupta (MD Pharmacology)