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Sucralfate is used to treat stomach ulcers, bowel ulcers and inflammation of the stomach.

How it works

Sucralfate belongs to a category of drugs called as ulcer-healing medications. It works by forming a protective lining over the ulcer and protects it from acid, bile salts and enzymes.

Common side effects

Nausea, Dry mouth, Indigestion, Constipation, Rash


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Expert advice

  • Do not take the medicine If you are allergic to it or to any other content in the medicine.
  • Take sucralfate on an empty stomach, at least 1 hour before or 2 hours after a meal.
  • Avoid taking any other medications within 2 hours before or after you take sucralfate.
  • Do not drive or operate heavy machinery after taking this medicine as it may make you feel dizzy.

Frequently asked questions


Q. Is sucralfate an antibiotic/sulfa drug/pain-killer/PPI?
Sucralfate is not an antibiotic/sulfa drug/ PPI (proton-pump inhibitor) or a pain-killer. It is an ulcer protective medicine.
Q. Is sucralfate available or sold over the counter?
No. Sucralfate is a prescription drug. It is not available or sold over the counter.
Q. Is sucralfate gluten free?
Yes. Sucralfate is gluten free. However, please refer to package insert of the prescribed brand before use.
Q. Is sucralfate safe?
Yes. Sucralfate is relatively safe if used as recommended. In case of any side-effects, consult your doctor.
Q. Can I take sucralfate with Prilosec/Nexium/ Tylenol/Zantac/ibuprofen/Pepto?
Yes. Sucralfate can be taken with Prilosec/Nexium/ Tylenol/Zantac/ibuprofen and Pepto if prescribed by your doctor.
Q. Does sucralfate cause headaches/weight gain/insomnia/ heartburn?
Sucralfate does not cause headaches/weight gain/insomnia or heartburn. If you experience any such symptoms, please consult your doctor.
Q. Is sucralfate a narcotic drug?
No. Sucralfate is not a narcotic drug.

Content on this page was last updated on 03 October, 2016, by Dr. Varun Gupta (MD Pharmacology)