


Progestad 500mg Tablet
Hydroxyprogesterone (500mg)
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Progestad 500mg Tablet is used to prevent premature labor in pregnant women in order to reduce the risk of giving birth too early (preterm birth). It prevents miscarriage and lower the risk of premature birth in women who have had one premature delivery in the past.
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 02 Dec 2025 | 11:56 AM (IST)
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 02 Dec 2025 | 11:56 AM (IST)
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General Information
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Product introduction
Progestad 500mg Tablet should be taken as your doctor advice. Your doctor will decide how much you need to take and for how much time. You may take it with or without food but better to take it at a fixed time. You should take this medicine for as long as it is prescribed for you.
There is limited data on the side effects of Progestad 500mg Tablet. Let your doctor know if you experience any symptoms that bother you or worsen while taking the medicine. They may be able to suggest ways to treat or manage the side effects.
Before you start Progestad 500mg Tablet, let your doctor know if you have any medical conditions. Inform your doctor about all the medications you are taking, as some medicines may interact with Progestad 500mg Tablet.
Uses of Progestad Tablet
Benefits of Progestad Tablet
Prevention of Premature Labor
Progestad 500mg Tablet is a man-made, injectable form of the female hormone called progesterone, that helps lower the risk of delivering the baby too early (premature labor), particularly in women who have had this complication in an earlier pregnancy. Progesterone is a hormone that thickens the lining of the uterus and prepares it for the growth and development of the baby. So, it helps your uterus grow during pregnancy and also prevents any contractions that can otherwise lead to miscarriage.
Progestad 500mg Tablet is a man-made, injectable form of the female hormone called progesterone, that helps lower the risk of delivering the baby too early (premature labor), particularly in women who have had this complication in an earlier pregnancy. Progesterone is a hormone that thickens the lining of the uterus and prepares it for the growth and development of the baby. So, it helps your uterus grow during pregnancy and also prevents any contractions that can otherwise lead to miscarriage.
Side effects of Progestad Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Progestad
- Limited data available
How to use Progestad Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Progestad 500mg Tablet may be taken with or without food.
Avoid Progestad 500mg Tablet with caffeine and chocolate as well as food containing caffeine and chocolate such as tea leaves, cocoa beans.
Avoid Progestad 500mg Tablet with caffeine and chocolate as well as food containing caffeine and chocolate such as tea leaves, cocoa beans.
How Progestad Tablet works
Progestad 500mg Tablet is a progestin (female hormone).
Quick tips
- Progestad 500mg Tablet is used in pregnant women to help lower the risk of giving birth too early (preterm birth).
- It is only given to a woman who has had a preterm delivery in the past.
- It is not for use in women who are pregnant with more than one baby (twins, triplets, etc.).
- Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain. These could be symptoms of a serious liver problem.
- Inform your doctor immediately if you have pain in the chest, groin or legs, difficulty with breathing, sudden severe headache, slurred speech, sudden unexplained shortness of breath, a sudden loss of coordination, or vision changes while using this medicine.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Progestad 500mg Tablet. Please consult your doctor.

Pregnancy
SAFE IF PRESCRIBED
Progestad 500mg Tablet is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.

Breast feeding
SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.

Driving
SAFE
Progestad 500mg Tablet does not usually affect your ability to drive.

Kidney
CONSULT YOUR DOCTOR
There is limited data available on the use of Progestad 500mg Tablet in patients with kidney disease. Please consult your doctor.
This medicine contains progesterone which can cause fluid retention in patients with underlying kidney disease.
This medicine contains progesterone which can cause fluid retention in patients with underlying kidney disease.

Liver
CONSULT YOUR DOCTOR
There is limited data available on the use of Progestad 500mg Tablet in patients with liver disease.
Interaction with drugs
Taking Progestad with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe
Tamoxifen (Oral Route)
Do not consume Tamoxifen with Hydroxyprogesterone if you have or had breast cancer. If essential, consult your doctor. Hydroxyprogesterone may reduce the efficacy of Tamoxifen.
Severe
Letrozole (Oral Route)
Do not consume Letrozole with Hydroxyprogesterone if you have or had breast cancer. If essential, consult your doctor.
Severe
Anastrozole (Oral Route)
Do not consume Anastrozole with Hydroxyprogesterone if you have or had breast cancer. If essential, consult your doctor. Hydroxyprogesterone may reduce the efficacy of Anastrozole.
Severe
Raloxifene (Oral Route)
Do not consume Raloxifene with Hydroxyprogesterone. If concurrent use is essential, please consult your doctor. Hydroxyprogesterone may reduce the efficacy of Raloxifene.
Severe
Darunavir (Oral Route)
It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may monitor your treatment closely and adjust the doses as per the observations. Use barrier methods (like condoms) for contraception to reduce the risk of HIV infection.
Frequently asked questions
Progestad 500mg Tablet is a type of female sex hormone. It helps to lower the risk of preterm delivery (early birth) in a pregnant woman, who had delivered a preterm baby in the past.
Progestad 500mg Tablet should be taken in the dose decided by your doctor. Your dose will depend on your exact medical condition. It can be taken with or without food. It is advisable to take Progestad 500mg Tablet at a fixed time each day to avoid the chances of missing a dose.
Ideally, you should try not to miss any dose. However, if you miss a dose consult with your doctor as soon as you remember. You may consider taking the medicine at the same time or linking any particular daily activity like having food to fix a set time for medicine. You can also try pill reminders or pill boxes.
The common side effects of Progestad 500mg Tablet include nausea, diarrhea and hives. However, most of these side effects are not severe and resolve once your body adjusts to the medicine. If any of these side effects bother you, please consult your doctor.
Progestad 500mg Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Fact Box
Chemical Class
Gluco/mineralocorticoids, progestogin derivative
Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL
Action Class
Progestins (First generation)
References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 671-72.
- MedIndia. HYdroxyprogesterone. [Accessed 03 Apr. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Adbio Organics Pvt Ltd
Address: SCF -436, Second Floor ,Motor Market, Manimajra, Chandigarh-160101( U.T.)
Address: SCF -436, Second Floor ,Motor Market, Manimajra, Chandigarh-160101( U.T.)
Vendor Details
Country of origin: India
Lab tests offered by us
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- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
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