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    Letrozole

    Information about Letrozole

    Letrozole uses

    Letrozole is used in the treatment of infertility and breast cancer.

    How letrozole works

    Letrozole is an aromatase inhibitor. It works by lowering the amount of estrogen (natural female hormone) produced in the body. This can lower or stop the growth of some breast cancer cells that need estrogen to grow.

    Common side effects of letrozole

    Hypercholesterolaemia, Hot flushes, Increased sweating, Musculoskeletal (bone, muscle or joint) pain, Fatigue

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    Expert advice for Letrozole

    • Letrozole should not be given to children and adolescents up to 17 years of age.
    • Do not drive or operate heavy machinery as you feel dizzy, tired, drowsy or unwell while taking letrozole.
    • Do not take letrozole if you are allergic to letrozole or any other ingredient of tablet or intolerance to some sugars (lactose).
    • Do not take letrozole if you still have menstrual periods; severe liver or kidney disease; history of or are susceptible to brittle bones (osteoporosis) or bone fracture.
    • Avoid using letrozole if you are pregnant or breast-feeding.

    Frequently asked questions for Letrozole

    Letrozole

    Q. Is Letrozole a steroid, a hormone, a selective estrogen receptor modulator, or cytotoxic?

    Letrozole is not a steroid, hormone, selective estrogen receptor modulator or cytotoxic drug. Letrozole is an aromatase inhibitor.

    Q. Can I take Letrozole with ibuprofen/Advil, vitamins, paracetamol, glucosamine, magnesium, zinc?

    Letrozole can be taken with ibuprofen/Advil, vitamins, paracetamol, glucosamine, magnesium, and zinc. However, please consult your doctor before use.

    Q. Does Letrozole cause hair loss, headache, insomnia, water retention, high blood pressure, bloating, and acne?

    Letrozole may cause hair loss, headache, insomnia, bloating, and high blood pressure. Letrozole does not cause water retention and acne.

    Content on this page was last updated on 20 June, 2018, by Dr. Varun Gupta (MD Pharmacology)