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Hydroxyprogesterone

Written By Dr. Anuj SainiReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:34 AM (UTC)

Hydroxyprogesterone Uses

Hydroxyprogesterone is used in premature labor.

How Hydroxyprogesterone works

Hydroxyprogesterone is a progestin (female hormone).

Common side effects of Hydroxyprogesterone

Injection site pain, Injection site swelling, Red spots or bumps
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Expert advice for Hydroxyprogesterone

  • Hydroxyprogesterone is used in pregnant women to help lower the risk of giving birth too early (preterm birth).
  • It is only given to a woman who has had a preterm delivery in the past.
  • It is not for use in women who are pregnant with more than one baby (twins, triplets, etc.).
  • It is administered only by or under the immediate supervision of your doctor. Your doctor can start giving you the injection every week between 16 and 20 weeks and continue through week 37, or until you deliver.
  • It may affect blood sugar levels. Monitor your blood sugar regularly.
  • Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain. These could be symptoms of a serious liver problem.
  • Inform your doctor immediately if you have pain in the chest, groin or legs, difficulty with breathing, sudden severe headache, slurred speech, sudden unexplained shortness of breath, a sudden loss of coordination, or vision changes while using this medicine.

Frequently asked questions for Hydroxyprogesterone

Hydroxyprogesterone is a type of female sex hormone called progesterone. It helps to lower the risk of preterm delivery (early birth) in a pregnant woman, who had delivered a preterm baby in the past.
Hydroxyprogesterone is given as an injection, by a doctor or trained nurse. The dose will be decided by your doctor, depending on your exact medical condition.
Ideally, you should try not to miss any dose. However, if you miss a dose consult with your doctor as soon as you remember.