Pregtec 500 mg Injection is a progestin (female hormone). It works by modulating the immune response of the mother to prevent rejection of the embryo and allow its attachment to the uterus. This prevents miscarriage and helps lower the risk of premature birth in women who have had one premature delivery in the past.
Tell your doctor if you have diabetes, pre-diabetes (high blood sugar levels, but not high enough to be called diabetes) or a family history of diabetes, before taking hydroxyprogesterone.
If you are suffering from high blood pressure during pregnancy (preeclampsia), fits (epilepsy), heart or kidney functioning problems, you should be monitored for fluid retention while on treatment with Hydroxyprogesterone.
Tell your doctor if you have severe pulsating headaches (migraines), asthma, history of depression or high blood pressure (hypertension), before taking Hydroxyprogesterone.
Seek immediate medical attention if you notice any signs of depression or jaundice.
Consult your doctor regarding continuing treatment with hydroxyprogesterone after delivery and during breastfeeding.
Interaction with alcohol is unknown. Please consult your doctor.
Pregtec 500 mg Injection is probably safe to use during pregnancy. Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Pregtec 500 mg Injection is safe to use during lactation.
Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby. Nonhormonal contraceptives are preferred in breastfeeding women, especially during the first 4 weeks postpartum
Pregtec 500 mg Injection does not usually affect your ability to drive.
There is limited information available on the use of Pregtec 500 mg Injection in patients with kidney disease. Please consult your doctor. This medicine contains progesterone which can cause fluid retention in patients with underlying kidney disease.
There is limited information available on the use of Pregtec 500 mg Injection in patients with liver disease. Please consult your doctor.
Q. Is hydroxyprogesterone the same as progesterone?
No. Progesterone is a natural sex hormone produced by the body and hydroxyprogesterone is its synthetic form. Both have different physiological effects and are used for the treatment of different conditions
Q. Is hydroxyprogesterone safe?
It is relatively safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 20th Mar 2018.