P&F 650mg Tablet helps relieve pain and fever by blocking the release of certain chemical messengers responsible for fever and pain. It is used to treat headaches, migraine, toothaches, sore throats, period (menstrual) pains, arthritis, muscle aches, and the common cold.

P&F 650mg Tablet may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor. It is usually best taken with food otherwise it may upset your stomach. Do not take more or use it for longer than recommended.

Side effects are rare if this medicine is used correctly but this medicine may cause stomach pain, nausea, and vomiting in some people. Consult your doctor if any of these side effects bother you or do not go away.

This medicine is widely prescribed and considered safe but is not suitable for everybody. Before taking it, let your doctor know if you have liver or kidney problems or are using blood-thinning medicines. It may affect the dose or suitability of this medicine. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Uses of P&F Tablet

Benefits of P&F Tablet

In Pain relief

P&F 650mg Tablet is a common painkiller for treating aches and pains. It is widely used and rarely causes any side effects if taken properly. To get the most benefits, take it as prescribed. Do not take more or for longer than needed as that can be dangerous.

In Treatment of Fever

P&F 650mg Tablet is also used to reduce a high temperature (fever). It works by blocking the release of certain chemical messengers that cause fever. It may be prescribed alone or in combination with other medicines. Take it as prescribed by the doctor.

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Side effects of P&F Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of P&F

Stomach pain
Nausea
Vomiting

How to use P&F Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. P&F 650mg Tablet is to be taken with food.

How P&F Tablet works

P&F 650mg Tablet is an analgesic (pain reliever) and anti-pyretic (fever reducer). It works by blocking the release of certain chemical messengers that cause pain and fever.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with P&F 650mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

P&F 650mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

P&F 650mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving

SAFE

P&F 650mg Tablet does not usually affect your ability to drive.

Kidney

CAUTION

P&F 650mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of P&F 650mg Tablet may be needed. Please consult your doctor.
However, P&F 650mg Tablet contains paracetamol which is considered the safest painkiller for kidney disease patients.

Liver

CAUTION

P&F 650mg Tablet should be used with caution in patients with liver disease. Dose adjustment of P&F 650mg Tablet may be needed. Please consult your doctor.
However, the use of P&F 650mg Tablet is not recommended in patients with severe liver disease and active liver disease.

What if you forget to take P&F Tablet?

If you miss a dose of P&F 650mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

P&F 650mg Tablet

₹1.8/Tablet

Pyrigesic 650 Tablet

East India Pharmaceutical Works Ltd

₹2.06/tablet

14% costlier

PUC 650 Tablet

Alkem Laboratories Ltd

₹1.9/tablet

6% costlier

Glenpar 650mg Tablet

Glenmark Pharmaceuticals Ltd

₹1.84/tablet

2% costlier

Zypara 650mg Tablet

Zydus Cadila

₹1.97/tablet

9% costlier

Flexon 650 Tablet

Aristo Pharmaceuticals Pvt Ltd

₹1.93/tablet

7% costlier

View all substitutes

Quick tips

P&F 650mg Tablet should be taken with food or milk to prevent an upset stomach.
Take it as per the dose and duration prescribed by your doctor. Long-term use may lead to serious complications such as stomach bleeding and kidney problems.
Do not take indigestion remedies (antacids) within two hours of taking P&F 650mg Tablet.
Avoid consuming alcohol while taking this medicine as it can increase your risk of stomach problems.
Inform your doctor if you have liver disease as your dose may need to be adjusted.
The doctor may regularly monitor your kidney function, liver function, and levels of blood components if you are taking P&F 650mg Tablet for long-term treatment.

Fact Box

Chemical Class

P-Aminophenol Derivative

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

Analgesic & Antipyretic-PCM

Interaction with drugs

Taking P&F with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Certoparin (Injection Route) Moderate

Concurrent use may increase the risk of liver damage. If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and ... More

Cholestyramine (Oral Route) Moderate

Paracetamol may increase the effect of Cholestyramine. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Dalteparin (Injection Route) Moderate

Concurrent use may increase the risk of liver damage. If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and ... More

Enoxaparin (Injection Route) Moderate

Concurrent use may increase the risk of liver damage. If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and ... More

Bemiparin (Injection Route) Moderate

Concurrent use may increase the risk of liver damage. If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and ... More

View all drug interactions

Patient concerns

I have two days fever, I take sinarest and cefran 500 mg tablet , but not relief please sussed me.

Dr. Sfurti Mann

Internal Medicine

Take tab zerodol p twice daily for fever

Infection near nail of little finger

Dr. Sfurti Mann

Internal Medicine

Take tab zerodol p for pain relief Get CBC and RBS checked

My Daughter has fever, and she is taking meftal p suspension. But the fever is not going off, also she complains about abdominal pain From last 3 days she has fever measured 103 and 104 f

Dr. Gopal Bansilal Samdani

Paediatrics

Monitor temperature of Patient. If Patient has fever place a cool, damp washcloth on your child's forehead. Give your Patient a lukewarm tub bath or a sponge bath. Give a sponge bath as follows: - ? Use lukewarm water [90?F (32.2?C) to 95?F (35?C)]. Do not use cold water, ice, or rubbing alcohol, which will lower the child's body temperature too quickly. ? Sponge for 20 to 30 minutes. ? Stop if the child starts to shiver. If your child doesn't like the sponge bath or doesn't feel better after the bath, there is no need to give another one. You can use Paracetamol also along with above measures to control fever till you consult Dr. will determine underlying disorders by clinical examination which range from mild conditions to the most serious of bacterial and viral illnesses and will prescribe medicines accordingly.Dr need a final diagnosis or provisional diagnosis to suggest you investigations or medicine or give opinion. In present situation diagnosis cannot be done without taking in to consideration details of history and findings of clinical examination of patient. Advice given without doing clinical examination can be imperfect or some time harmful to patient.There are many underlying causes of Patient?s symptoms. Different cause needs different treatment. Specific treatment cannot be given unless we establish exact underlying cause. Final and perfect diagnosis cannot be done without doing clinical examination of patient. Please consult me or any other Paediatrician. will take detail history and will examine patient in detail. All information will be used to determine exact underlying cause of problem. Depending upon cause will prescribe you treatment. At time may ask you relevant investigations if necessary.

FAQs

What if I vomit after taking P&F 650mg Tablet?

If you vomit in less than 30 minutes after having a dose of P&F 650mg Tablet tablets or syrup, retake the same dose again. If you vomit after 30 minutes of a dose, you do not need to take another one until the next standard dose.

When will I feel better after taking the P&F 650mg Tablet?

Usually, you will start feeling better after about half an hour of taking a P&F 650mg Tablet.

How often can I take the P&F 650mg Tablet?

You should only take four doses of P&F 650mg Tablet in 24 hours. There should be a gap of at least 4 hours between two doses. Do not take P&F 650mg Tablet for more than 3 days without consulting a doctor first.

Is P&F 650mg Tablet an antibiotic?

No, P&F 650mg Tablet is not an antibiotic. It works as a painkiller and fever-reducing medicine.

Can I take P&F 650mg Tablet and ibuprofen together?

Ibuprofen and P&F 650mg Tablet are safe medicines, but both should not be used together. Consult your doctor if you are not sure.

How long does a P&F 650mg Tablet take to work?

P&F 650mg Tablet takes around 30-45 min to start working and show its effects. It is advised to take this medicine for the duration suggested by the doctor. Consult your doctor if you experience any bothersome side effects.

What are the serious side effects of taking an excess of the P&F 650mg Tablet?

Overdose of P&F 650mg Tablete may cause severe life-threatening liver injury. Taking more than the prescribed dose may also cause kidney injury, decreased platelet count, and even coma. Early symptoms of an overdose include nausea, vomiting, and general tiredness. Immediately consult a doctor or reach an emergency in case of a suspected overdose.

Can P&F 650mg Tablet cause nausea and vomiting?

Yes, P&F 650mg Tablet may cause nausea and vomiting. Taking it with milk, food or antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine or a low frequency of urination. Do not take any other medicines without speaking to your doctor.<br>

Is P&F 650mg Tablet helpful in relieving stomach pain due to indigestion?

No, P&F 650mg Tablet should not be taken for stomach pain without consulting a doctor. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.

Can I take P&F 650mg Tablet with an antibiotic?

Yes, taking P&F 650mg Tablet and antibiotics at the same time should not cause any problems. Antibiotics are used to help clear infections but often don't do anything to relieve pain. Therefore you can generally take P&F 650mg Tablet alongside your antibiotics. However, always consult your doctor before taking any medications.

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Related lab tests

Complete Blood Count

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 635-36.
Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 982-84.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 8-12.
Paracetamol. County Tipperary, Ireland: Pinewood Healthcare; 2015. [Accessed 17 Jun. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 02 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:

Marketer details

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Address: Plot No. 45, N.T.M., Sector -26, Chandigarh

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.