Osicare 500mg Tablet

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 26 Jan 2026 | 10:16 PM (IST)

Osicare 500mg Tablet is a medicine used in the treatment of osteoarthritis. It helps in the formation of cartilage and keeps the joints lubricated for better movement and flexibility. This way it relieves the pain and swelling in the joints.

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MRP ₹35.16

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Gluconol 500mg Tablet

₹77.6~~₹126.56~~

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Osicare 500mg Tablet

strip of 10 tablets

₹35.16

Same composition

Gluconol 500mg Tablet

strip of 10 tablets

Glucosamine (500mg)

by Knoll Pharmaceuticals Ltd

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₹77.6

₹6.6 per tablet

₹66

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General Information

Contains

Glucosamine (500mg)

Marketer

Systopic Laboratories Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Osicare 500mg Tablet is to be taken with food. Take it regularly and do not stop taking the medicine even if you get better until that doctor tells you it is alright to stop. Along with taking the medicine, exercise regularly to strengthen muscles around the affected joint and manage your weight.

The use of this medicine may cause some common side effects like nausea, stomach upset, and heartburn. If these side effects do no go away with time or bother you, talk to your doctor. Your doctor may help with ways to reduce or prevent these symptoms.

To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your heart, kidneys, or liver. Also, tell your doctor about all the medicines you are taking. If you are pregnant or breastfeeding, you should consult your doctor before taking this medicine.

Uses of Osicare Tablet

Osteoarthritis

Benefits of Osicare Tablet

Osteoarthritis
Osteoarthritis is a joint condition caused by the gradual wear and tear of cartilage, leading to pain, stiffness, and reduced movement. Osicare 500mg Tablet helps support joint health by maintaining cartilage structure and reducing joint discomfort. This can improve joint flexibility, ease stiffness, and support better mobility during daily activities.

Side effects of Osicare Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Osicare

Nausea
Heartburn
Upset stomach

How to use Osicare Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Osicare 500mg Tablet should be taken with or after food.

How Osicare Tablet works

Osicare 500mg Tablet is a proteoglycan synthesis stimulator that relieves osteoarthritis symptoms. It helps in the formation of cartilage (the soft tissue that cushions the joints) and keeps the joints lubricated for better movement and flexibility.

All substitutes for Osicare 500mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Gluconol 500mg Tablet

by Knoll Pharmaceuticals Ltd

₹7.76/tablet

120% costlier

Quick tips

Osicare 500mg Tablet is used in the treatment of osteoarthritis.
Inform your doctor if you have a history of being allergic to shellfish or to glucosamine.
You will be asked to monitor your blood glucose level while taking Osicare 500mg Tablet.
Inform your doctor if you are taking any blood thinners like warfarin or if you have any scheduled surgery.
Let your doctor know if you are pregnant or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Osicare 500mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Osicare 500mg Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

UNSAFE

Osicare 500mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Osicare 500mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Osicare 500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Osicare 500mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Osicare with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Acenocoumarol (Oral Route)

Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine). Your doctor may monitor your blood clotting ability frequently.

Moderate

Warfarin (Oral Route)

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your blood sugar level. Glucosamine may raise blood levels of the active form of Warfarin.

Mild

Gliclazide (Oral Route)

Monitor your blood glucose levels regularly and talk to your doctor if you notice any unusual symptoms during the simultaneous use of these medicines.

Mild

Glibenclamide (Oral Route)

Monitor your blood glucose levels regularly and talk to your doctor if you notice any unusual symptoms during the simultaneous use of these medicines.

Mild

Metformin (Oral Route)

Monitor your blood glucose levels regularly and talk to your doctor if you notice any unusual symptoms during the simultaneous use of these medicines.

Frequently asked questions

Does Osicare 500mg Tablet actually work in joint pain?

The evidence on the effectiveness of Osicare 500mg Tablet in reducing pain is controversial. Some patients report that Osicare 500mg Tablet has helped reduce arthritis pain, stiffness, and mild to moderate osteoarthritis pain. In fact, there is some evidence that Osicare 500mg Tablet has beneficial effects on the cartilage by slowing down the cartilage breakdown in the joints.

Can Osicare 500mg Tablet cause liver damage?

In research studies, Osicare 500mg Tablet has not been found to raise the liver enzymes or cause any damage. However, there are few recent reports of liver injury while using the products containing Osicare 500mg Tablet. The chances of liver injury are more if the patient has been suffering from chronic liver disease.

Is Osicare 500mg Tablet bad for kidneys?

The effect of Osicare 500mg Tablet on kidneys is not confirmatory. Osicare 500mg Tablet is mostly metabolized and broken down by the liver. However, there are some reports of kidney damage caused due to Osicare 500mg Tablet, but there is a lack of conclusive evidence. Therefore, it should be used with caution in patients with kidney damage and kidney function should be regularly monitored. Do consult your doctor before you start using this medication. Also, inform your doctor if you have any kidney disease.

What are the precautions I should follow while taking Osicare 500mg Tablet?

Do consult your doctor before you start taking this medication and ensure to be cautious if you have diabetes or high blood glucose levels, high risk of heart disease or asthma. You should also be cautious if you are allergic to shellfish or are taking blood-thinning medicines like warfarin. Do tell your doctor if you have any of the above conditions before he prescribes you this medication.

Is it safe to take Osicare 500mg Tablet while taking blood-thinning medication?

No, it is not safe to take Osicare 500mg Tablet while taking blood-thinning medications like warfarin or coumadin. The reason being, this medication interacts with the blood thinners and boosts the effect of the blood-thinning medication, thereby reducing the blood’s ability to form a clot in case of bleeding episodes. Therefore, patients taking any blood-thinning medicine should consult their doctor before starting this medication.

Fact Box

Chemical Class

Hexoses

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

Proteoglycan Synthesis Stimulator

Related lab tests

Calcium

Rheumatoid Factor IgG Antibody

Rheumatoid Factor IgM Antibody

References

Dennehy CE, Tsourounis C. Dietary Supplements & Herbal Medications. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1123.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 633-34.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
Glucosamine sulfate [Summary of Product Characteristics]. Dublin, Ireland: Mylan IRE Healthcare Limited; 2025.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Systopic Laboratories Pvt Ltd
Address: 101, Pragati Chambers, Commercial Complex, Ranjit Nagar, New Delhi-110008

Vendor Details

Country of origin: India

Osicare 500mg Tablet

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Osicare Tablet

Benefits of Osicare Tablet

Side effects of Osicare Tablet

How to use Osicare Tablet

How Osicare Tablet works

All substitutes for Osicare 500mg Tablet

Gluconol 500mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Acenocoumarol (Oral Route)

Warfarin (Oral Route)

Gliclazide (Oral Route)

Glibenclamide (Oral Route)

Metformin (Oral Route)

Frequently asked questions

Does Osicare 500mg Tablet actually work in joint pain?

Can Osicare 500mg Tablet cause liver damage?

Is Osicare 500mg Tablet bad for kidneys?

What are the precautions I should follow while taking Osicare 500mg Tablet?

Is it safe to take Osicare 500mg Tablet while taking blood-thinning medication?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Calcium

Rheumatoid Factor IgG Antibody

Rheumatoid Factor IgM Antibody

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests