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Glibenclamide

INFORMATION

Uses

Glibenclamide is used in the treatment of type 2 diabetes.

How it works

Glibenclamide increases the amount of insulin released by the pancreas in order to lower the blood glucose.

Common side effects

Nausea, Anxiety, Bruise, Bleeding, Dark colored urine, Diarrhoea, Fever, Dizziness, Flatulence, Loss of appetite, Rash, Itching, Skin redness, Sore throat, Stomach pain / epigastric pain

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Expert advice

  • Type 2 diabetes can be controlled with a proper diet alone or a diet along with exercise. A planned diet and exercising are always important when you have diabetes, even when you are taking antidiabetic medicines.
  • Low blood sugar is life-threatening. Low blood sugar may develop due to:
    • Delay or missing scheduled meals or snacks. 
    • Exercising more than usual. 
    • Drinking a significant amount of alcohol.
    • Using too much insulin. 
    • Sickness (vomiting or diarrhea).
  • Symptoms of low blood sugar (alarming signs) are fast heartbeat, sweating, cool and pale skin, feeling shaky, confusion or irritability, headache, nausea, and nightmares. Make sure that you have access to quick-acting sugar sources that treat low blood sugar. Consuming some form of quick-acting sugars immediately after the appearance of the symptoms will prevent the low blood sugar levels from worsening.
  • Consuming alcohol may increase the chance of severe low blood sugar.
  • Glibenclamide does not help patients who have type 1 diabetes.

Frequently asked questions

Glibenclamide

Q.Is glibenclamide/Daonil/Euglucon same as glyburide?
Yes. Daonil/ Euglucon are the trade names for the active substance (generic) glibenclamide/ glyburide; thus, they all are same

Q.Is glibenclamide same as glipizide?
No. Glibenclamide and glipizide are different medicines; however, they belong to same family of drugs called sulfonylureas

Q.Why is glibenclamide avoided in the elderly?
Glibenclamide should be avoided in elderly patients because they are at high risk of getting low blood sugar (hypoglycemic event)

Q.What is glibenclamide/Daonil/ Euglucon used for?
Glibenclamide/Daonil/ Euglucon is used for the treatment of type 2 diabetes

Q.Does Daonil/ glibenclamide cause weight gain/ weight loss?
Yes Daonil/ glibenclamide are known to cause weight gain but not weight loss. Always consult your doctor if you experience such side effects.


Content on this page was last updated on 05 December, 2016, by Dr. Varun Gupta (MD Pharmacology)