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Glibenclamide is used in the treatment of type 2 diabetes

How it works

Glibenclamide increases the amount of insulin released by the pancreas, which in turn lowers the blood glucose levels.

Common side effects

Hypoglycemia (Low blood sugar level), Nausea, Headache, Dizziness

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Expert advice

  • The most common and serious side effect is hypoglycemia (low blood sugar level). If you consume excessive alcohol or if you have irregular dietary patterns, you are at an increased risk of hypoglycemia (low blood sugar level). Do not skip meals when taking this medicine.
  • Please be aware of signs and symptoms of low blood sugar (dizziness, tremor, sweating, headache).
  • Inform your doctor if you have ever been diagnosed with kidney or liver problems.
  • Tell your doctor if you are planning to get pregnant or pregnant or breastfeeding.
  • It should be avoided or use with caution if you are also taking nonsteroidal anti-inflammatory agents (NSAIDs), alcohol, β-blockers and ACE inhibitors.
  • Do not change the dose without consulting your doctor.

Frequently asked questions



Is glibenclamide/Daonil/Euglucon same as glyburide?
Yes. Daonil/ Euglucon are the trade names for the active substance (generic) glibenclamide/ glyburide; thus, they all are same


Is glibenclamide same as glipizide?
No. Glibenclamide and glipizide are different medicines; however, they belong to same family of drugs called sulfonylureas


Why is glibenclamide avoided in the elderly?
Glibenclamide should be avoided in elderly patients because they are at high risk of getting low blood sugar (hypoglycemic event)

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What is glibenclamide/Daonil/ Euglucon used for?
Glibenclamide/Daonil/ Euglucon is used for the treatment of type 2 diabetes


Does Daonil/ glibenclamide cause weight gain/ weight loss?
Yes Daonil/ glibenclamide are known to cause weight gain but not weight loss. Always consult your doctor if you experience such side effects.

Content on this page was last updated on 10 March, 2017, by Dr. Varun Gupta (MD Pharmacology)