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ONVINC 1 MG INJECTION

Injection
MRP: Rs. 48.07 for 1 vial(s) (1 injection each)
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Composition for ONVINC

Vincristine(1 mg)

food interaction for ONVINC

alcohol interaction for ONVINC

pregnancy interaction for ONVINC

lactation interaction for ONVINC

food
alcohol
pregnancy
lactation
It can be taken with or without food, but it is better to take Onvinc 1 mg injection at a fixed time.
Avoid Onvinc 1 mg injection with grapefruit juice.
UNSAFE
Interaction with alcohol is unknown. Please consult your doctor.
Onvinc 1 mg injection is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
WEIGH RISKS VS. BENEFITS
Onvinc 1 mg injection is probably unsafe to use during breastfeeding. Please consult your doctor.
UNSAFE

SALT INFORMATION for ONVINC

Vincristine(1 mg)

Uses

Onvinc 1 mg injection is used in the treatment of breast cancer, non-small cell lung cancer, pancreatic cancer, kidney cancer, blood cancer, multiple myeloma, lymphomas and bone cancer.

How it works

Onvinc 1 mg injection belongs to a group of medicines called vinca alkaloids. It works by interfering with the growth of cancer cells (mitotic inhibition) and slows their spread in the body by causing an arrest of cell division in metaphase.

Common side effects

Nerve pain, Loss of deep-tendon reflexes, Muscle atrophy, Constipation, Hair loss, Decreased white blood cell count, Sensory loss, Walking difficulties, Abnormal sensation in skin

SUBSTITUTES for ONVINC

11 Substitutes
Sorted By
RelevancePrice
  • CYTOCRISTIN 1 MG INJECTION
    (1 ML injection in vial)
    Cipla Ltd
    Rs. 56.89/ML of injection
    generic_icon
    Rs. 56.89
    pay 18% more per ML of injection
  • CYTOCRISTIN AQUEOUS 1 MG INJECTION
    (1 ML injection in vial)
    Cipla Ltd
    Rs. 44.04/ML of injection
    generic_icon
    Rs. 44.04
    save 8% more per ML of injection
  • VINLON 1MG INJECTION
    (1 ML injection in vial)
    Celon Laboratories Ltd
    Rs. 50.79/ML of injection
    generic_icon
    Rs. 50.79
    pay 6% more per ML of injection
  • UNICRISTIN 1MG INJECTION
    (1 ML injection in vial)
    United Biotech Pvt Ltd
    Rs. 55/ML of injection
    generic_icon
    Rs. 55
    pay 14% more per ML of injection
  • BIOCRISTIN 1 MG INJECTION
    (1 injection in vial)
    Biochem Pharmaceutical Industries
    Rs. 52.63/injection
    Injection
    Rs. 52.63
    pay 9% more per injection

Expert advice for ONVINC

  • Avoid being near people suffering from infections (such as, cold, flu, contagious illnesses), as you may be more susceptible to infections, while on vincristine therapy, because of possibility of leukopenia.
  • Avoid even accidental contamination of eyes with vincristine as it may cause severe irritation.
  • Vincristine may cause acute kidney disease (nephropathy) related to uric acid level.
  • Care should be taken in elderly patients because they are more susceptible to neurotoxic effects of vincristine.
  • In males, vincristine may cause aspermia (lack of semen causing infertility); in females vincristine may cause amenorrhea (absence of menstruation), which may recover after some duration.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently asked questions for ONVINC

Vincristine

Q.Is vincristine cardiotoxic/ototoxic?
Vincristine when used in combination with other drugs has shown to be cardiotoxic/ototoxic with unknown cause

Q.Is vincristine an alkylating agent/ an anthracycline?
Vincristine is vinca alkaloid and not an alkylating agent/ an anthracycline

Q.Is vincristine a vesicant?
Vincristine is a vesicant (irritant) and can cause damage to the blood vessels if it is not administered properly

Q.Is vincristine non DNA binding?
Vincristine does not bind to DNA

Q.Is vincristine neuropathy reversible?
Vincristine neuropathy is not reversible

Q.Is vincristine FDA approved?
Vincristine is a FDA approved medication

Q.Is vincristine cytotoxic?
Vincristine is a cytotoxic drug

Q.Does vincristine cause hair loss/infertility/ lower blood counts/ neutropenia/ neuropathy/ fever/ nausea?
These side effects are commonly observed with the use of vincristine drug

Q.How does vincristine affect mitosis?
Vincristine works by interfering with the growth of cancer cells (mitotic inhibition) and slows their spread in the body by causing an arrest of cell division in metaphase

Q.Where does vincristine come from?
Vincristine is a plant alkaloid comes from the source called Vinca rosea Linn.

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Content on this page was last updated on 27 June, 2015, by Dr. Varun Gupta (MD Pharmacology)