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Mesalenz 1.2g Tablet DR

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 25 Nov 2025 | 03:05 PM (IST)
Mesalenz 1.2g Tablet DR is an anti-inflammatory medicine used to treat a type of bowel disease known as ulcerative colitis. It helps to reduce symptoms such as diarrhea, bleeding and stomach pain by reducing inflammation in the bowel.
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Mesalenz 1.2g Tablet DR is currently sold out
Same composition alternative:
Mesalo OD Tablet
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Mesalenz 1.2g Tablet DR
Mesalenz 1.2g Tablet DR
strip of 10 Tablet DR
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Mesalo OD Tablet
Mesalo OD Tablet
strip of 10 Tablet DR
by Cipla Ltd
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Mesalenz 1.2g Tablet DR image
Mesalenz 1.2g Tablet DR image
Mesalenz 1.2g Tablet DR image
Mesalenz 1.2g Tablet DR image
Mesalenz 1.2g Tablet DR image

Product introduction

Mesalenz 1.2g Tablet DR may also be used to treat another type of bowel disease known as Crohn’s ileocolitis. It should be taken with food. The dose will depend on what you are being treated for but take it exactly as your doctor prescribes. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen.

The most common side effects of this medicine include nausea, diarrhea, stomach pain, headache, itching, flatulence, and vomiting. If these symptoms bother you, do not go away, or get worse, let your doctor know. There may be ways of reducing or preventing them. Some people may get a severe allergic reaction that needs urgent medical attention. Contact your doctor immediately if you notice symptoms like swelling of the face, tongue, throat, or lips, unusual bleeding, bruising, rash, fever, sore throat, or excessive tiredness. 

Before taking it, tell your doctor if you have any kidney or liver problems or a blockage in your stomach. Your age may also be a factor in deciding whether this medicine is suitable. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

Uses of Mesalenz Tablet DR

Benefits of Mesalenz Tablet DR

Ulcerative colitis
Ulcerative colitis is a form of inflammatory bowel disease (IBD) that causes inflammation and ulcers in the colon and rectum. Mesalenz 1.2g Tablet DR helps reduce the inflammation in the intestinal lining by targeting the disease locally. Reduction in inflammation promotes mucosal healing and causes symptoms like abdominal pain, diarrhea, and rectal bleeding to subside.
Crohn’s disease
Crohn’s disease is a type of inflammatory bowel disease that can affect any part of the digestive tract, causing symptoms like abdominal pain, diarrhea, and fatigue. Mesalenz 1.2g Tablet DR is used in mild to moderate cases to reduce inflammation and manage flare-ups. It can help prevent disease progression, reduce the need for steroids, and support intestinal health over time.

Side effects of Mesalenz Tablet DR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Mesalenz
  • Flatulence
  • Headache
  • Vomiting
  • Diarrhea
  • Nausea
  • Abdominal pain
  • Rash
  • Stomach pain/epigastric pain

How to use Mesalenz Tablet DR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mesalenz 1.2g Tablet DR may be taken with or without food.

How Mesalenz Tablet DR works

Mesalenz 1.2g Tablet DR is an aminosalicylate. It works by suppressing the production of chemical messengers (prostaglandins) that cause inflammation (swelling) in the intestines. This reduces ulceration, bleeding and stomach pain, and prevents future flare-ups of the disease.

All substitutes for Mesalenz 1.2g Tablet DR

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • You have been prescribed Mesalenz 1.2g Tablet DR for treating and lowering the symptoms of mild inflammatory bowel disease such as ulcerative colitis.
  • Your doctor may monitor your kidney and liver functions before you start treatment with this medicine and regularly thereafter. Inform your doctor if you have severely decreased kidney or liver function.
  • Do not take Mesalenz 1.2g Tablet DR if you are allergic to aspirin or if you have blood disorders.
  • Do not stop taking the medication suddenly without talking to your doctor.
  • You have been prescribed Mesalenz 1.2g Tablet DR for treating and lowering the symptoms of mild inflammatory bowel disease such as ulcerative colitis.
  • Take it with food. Do not break, chew, or crush the tablets or granules. Swallow them whole with plenty of water.
  • Do not take antacids with Mesalenz 1.2g Tablet DR as it can make your inflammation worse.
  • Your doctor may monitor your kidney and liver functions before you start treatment with this medicine and regularly thereafter. Inform your doctor if you have severely decreased kidney or liver function.
  • Do not take Mesalenz 1.2g Tablet DR if you are allergic to aspirin or if you have blood disorders.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Mesalenz 1.2g Tablet DR.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Mesalenz 1.2g Tablet DR during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Mesalenz 1.2g Tablet DR may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
If you are taking Mesalenz 1.2g Tablet DR, monitor the baby for diarrhea.
Driving

Driving

SAFE
Mesalenz 1.2g Tablet DR does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Mesalenz 1.2g Tablet DR should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Mesalenz 1.2g Tablet DR is not recommended in patients with severe kidney disease.
Liver

Liver

CAUTION
Mesalenz 1.2g Tablet DR should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Mesalenz with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Clozapine (Oral Route)

Your doctor may monitor your blood cell count and adjust the doses as per the observations.
Moderate

Azathioprine (Oral Route)

If concurrent use can not be avoided, your doctor may monitor your blood cell counts.
Moderate

Deferiprone (Oral Route)

If concurrent use can not be avoided, your doctor may monitor your blood cell counts.
Moderate

Mercaptopurine (Oral Route)

If concurrent use cannot be avoided, your doctor may monitor your blood cell counts.
Mild

Chlorpromazine (Oral Route)

Talk to your doctor if you notice any unusual symptoms.

Frequently asked questions

Continue to take Mesalenz 1.2g Tablet DR as advised by the doctor, even if you feel better at the beginning of your treatment. Do not stop taking Mesalenz 1.2g Tablet DR without consulting your doctor.
You should avoid alcohol if you have ulcerative colitis, as alcohol will irritate your stomach and intestine which will worsen your condition. Although alcohol does not interfere with the working of Mesalenz 1.2g Tablet DR, you should consult your doctor before taking alcohol.
Yes, Mesalenz 1.2g Tablet DR may cause joint pain. If the pain continues and bothers you inform your doctor.
Take Mesalenz 1.2g Tablet DR exactly as directed by your doctor.

Fact Box

Chemical Class

Aminobenzoic acids

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

5-Aminosalicylic Acid (5-ASA)
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Splenz pharmaceuticals Pvt Ltd
Address: 49/b-k. k.market,dhankawadi, pune - 43

Vendor Details

Country of origin: India
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