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    Information about Chlorpromazine

    Chlorpromazine uses

    Chlorpromazine is used in the treatment of schizophrenia.

    How chlorpromazine works

    Chlorpromazine is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.

    Common side effects of chlorpromazine

    Sleepiness, Orthostatic hypotension (sudden lowering of blood pressure on standing), Dryness in mouth, Abnormality of voluntary movements, Weight gain, Increased prolactin level in blood, Urinary retention, Constipation, Muscle stiffness, Tremor
    Content Details
    Written By
    Dr. Swati Mishra
    Reviewed By
    Dr. Varun Gupta
    MD (Pharmacology), MBBS
    Last updated on:
    27 Dec 2019 | 01:08 PM (IST)
    Want to know more?
    Read Our Editorial Policy

    Available Medicine for Chlorpromazine

    • ₹3 to ₹9
      A N Pharmacia
      5 variant(s)
    • ₹14 to ₹22
      Triko Pharmaceuticals
      2 variant(s)
    • ₹3
      Orchid Chemicals & Pharmaceuticals Ltd
      1 variant(s)
    • ₹4 to ₹20
      Intas Pharmaceuticals Ltd
      5 variant(s)
    • ₹2 to ₹13
      7 variant(s)
    • ₹3 to ₹10
      Zee Laboratories
      3 variant(s)
    • ₹4
      Gujarat Terce Laboratories Ltd
      1 variant(s)
    • ₹3 to ₹7
      Osho Pharma Pvt Ltd
      3 variant(s)
    • ₹4
      Medo Pharma
      1 variant(s)
    • ₹4 to ₹7
      2 variant(s)

    Expert advice for Chlorpromazine

    • Do not use chlorpromazine in children < 1 year unless the need is lifesaving or in children ≤12 years for the treatment of hiccups.
    • Tell your doctor before taking chlorpromazine if you are suffering from liver or kidney disease, epilepsy, Parkinson’s disease, reduced activity of thyroid gland (hypothyroidism), heart disease, raised eyeball pressure (glaucoma), diabetes, tendency to form blood clots or a family history of clotting disorder, pheochromocytoma (high blood pressure due to a tumour near the kidney), or enlarged prostate.
    • Inform your doctor if you have known cardiovascular disease or family history of QT prolongation and if you are taking medicines that may prolong the QT interval.
    • Inform your doctor of other medications that you may be taking for psychiatric disorders, lowering of blood pressure, insomnia, fits, Parkinson’s disease, migraine etc.
    • Do not stop taking chlorpromazine or change its dose without consulting your doctor.
    • Monitor blood glucose regularly while on chlorpromazine treatment, if you are a patient with diabetes
    • Do not drive or operate heavy machinery after taking chlorpromazine as it may cause drowsiness and visual disturbances. 
    • Do not consume this drug if you are allergic to any phenothiazine drug, chlorpromazine or any of its ingredients.
    • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

    Frequently asked questions for Chlorpromazine


    Q. Is Chlorpromazine a benzodiazepine/sleeping tablet?

    Chlorpromazine is not a benzodiazepine. It belongs to a class of medicines called phenothiazine antipsychotics. Chlorpromazine should not be used as a sleeping tablet

    Q. Is it good for anxiety?

    It is used in patients with schizophrenia but it relieves anxiety too at certain levels

    Q. Is Chlorpromazine a controlled substance/narcotic?

    No. Chlorpromazine is not a controlled substance/ narcotic. However, it can be purchased only after producing a doctor's prescription

    Q. Does Chlorpromazine cause weight gain/sleepiness/euphoric (high)?

    Yes, Chlorpromazine may cause weight gain and sleepiness

    Q. Is it addictive?

    Chlorpromazine does not have high addictive potential and a very little propensity for abuse for euphoria

    Q. Does chlorpromazine decrease dopamine?

    Chlorpromazine is dopamine receptor blocker so it decreases dopamine levels to calm the patients with schizophrenia

    Q. Does Chlorpromazine help with opiate withdrawal?

    It has been observed that Chlorpromazine helps in certain cases of opiate withdrawal. However, it is not widely used for this purpose. Please follow your doctor's advice regarding its use.

    Content on this page was last updated on 27 December, 2019, by Dr. Varun Gupta (MD Pharmacology)